Protein aggregation in Huntington's and Parkinson's disease: implications for therapy. (Q34046301)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11006527%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

review article

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title

Protein aggregation in Huntington's and Parkinson's disease: implications for therapy (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11006527%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

0 references

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11006527%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

author name string

Wanker EE

series ordinal

1

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30 July 2017

publication date

1 October 2000

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11006527%20AND%20SRC:MED&resulttype=core&format=json

Trends in Molecular Medicine

31 October 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11006527%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

volume

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11006527%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

issue

10

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11006527%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

page(s)

387-391

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11006527%20AND%20SRC:MED&resulttype=core&format=json

Neuropathological classification of Huntington's disease

31 October 2019

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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

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Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

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Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join the (mis)fold

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Structural neurology: are seeds at the root of neuronal degeneration?

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Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

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Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

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Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

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Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

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Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

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Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

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Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

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Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

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A Drosophila model of Parkinson's disease

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Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo

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A cellular model that recapitulates major pathogenic steps of Huntington's disease

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Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

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Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis

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Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

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Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

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Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

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7 January 2021

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

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The ubiquitin pathway in Parkinson's disease

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7 January 2021

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7 January 2021

Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy

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7 January 2021

alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

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Synthetic filaments assembled from C-terminally truncated alpha-synuclein.

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7 January 2021

Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.

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7 January 2021

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11006527%20AND%20SRC:MED&resulttype=core&format=json

release_tyuqbohl3rc5tnhe65ebcs5or4

31 October 2019

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/tyuqbohl3rc5tnhe65ebcs5or4

24 November 2022

mapped directly with Wikidata item

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