A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis (Q34047242)

30 July 2017

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title

A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis (English)

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30 July 2017

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R Beyaert

1

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30 July 2017

K Heyninck

series ordinal

2

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30 July 2017

S Van Huffel

series ordinal

3

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30 July 2017

language of work or name

English

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publication date

1 October 2000

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30 July 2017

Biochemical Pharmacology

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30 July 2017

60

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30 July 2017

1143-1151

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30 July 2017

8

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Cytokine regulation of cellular adhesion molecule expression in inflammation

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New insights into the roles of ReL/NF-kappa B transcription factors in immune function, hemopoiesis and human disease

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Activate NF-kappa B or die?

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NF-kappaB and the innate immune response

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Mechanisms mediating caspase activation in cell death

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Toll signaling pathways in the innate immune response

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TRAF2 plays a dual role in NF-kappaB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkappaB kinase pathways.

7 January 2021

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p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

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Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

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IkappaB-NF-kappaB structures: at the interface of inflammation control

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I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction

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TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation

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A20 blocks endothelial cell activation through a NF-kappaB-dependent mechanism

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Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis

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Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction

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A20 RNA expression is associated with undifferentiated nasopharyngeal carcinoma and poorly differentiated head and neck squamous cell carcinoma

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Nuclear c-Myc plays an important role in the cytotoxicity of tumor necrosis factor alpha in tumor cells

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Nuclear factor kB-independent cytoprotective pathways originating at tumor necrosis factor receptor-associated factor 2

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The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases

7 January 2021

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TNF-induced mitochondrial changes and activation of apoptotic proteases are inhibited by A20.

7 January 2021

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Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

7 January 2021

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The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation

7 January 2021

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A20 inhibits NF-kappaB activation independently of binding to 14-3-3 proteins

7 January 2021

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The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN

7 January 2021

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Epstein-Barr virus-encoded LMP1 and CD40 mediate IL-6 production in epithelial cells via an NF-kappaB pathway involving TNF receptor-associated factors

7 January 2021

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Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.

7 January 2021

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IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice

7 January 2021

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A novel function for A20 in smooth muscle cells: inhibition of activation and proliferation

7 January 2021

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A20, an inhibitor of cell death, self-associates by its zinc finger domain

7 January 2021

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The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kappaB activation at the level of TRAF6

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Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

7 January 2021

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14-3-3 proteins associate with A20 in an isoform-specific manner and function both as chaperone and adapter molecules

7 January 2021

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Identification and cloning of a novel cellular protein Naf1, Nef-associated factor 1, that increases cell surface CD4 expression

7 January 2021

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Molecular characterization of NDP52, a novel protein of the nuclear domain 10, which is redistributed upon virus infection and interferon treatment

7 January 2021

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

7 January 2021

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

7 January 2021

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TRAF1 is a TNF inducible regulator of NF-kappaB activation.

7 January 2021

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TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

7 January 2021

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Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

7 January 2021

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CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival

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Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

7 January 2021

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The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

7 January 2021

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Nuclear factor kappa B: important transcription factor and therapeutic target

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The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

7 January 2021

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Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

7 January 2021

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Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice

7 January 2021

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Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators

7 January 2021

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

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Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

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IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.

7 January 2021

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A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets

7 January 2021

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Accommodation of vascularized xenografts: expression of "protective genes" by donor endothelial cells in a host Th2 cytokine environment

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Survival of accommodated cardiac xenografts upon retransplantation into cyclosporine-treated recipients

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Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes

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CREB-2, a cellular CRE-dependent transcription repressor, functions in association with Tax as an activator of the human T-cell leukemia virus type 1 promoter

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(00)00404-4

1 reference

30 July 2017

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