Signaling angiogenesis via p42/p44 MAP kinase and hypoxia (Q34047250)

30 July 2017

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title

Signaling angiogenesis via p42/p44 MAP kinase and hypoxia (English)

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30 July 2017

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9

J Pouysségur

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Julie Milanini

object named as

J Milanini

2

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author name string

E Berra

1

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30 July 2017

D E Richard

3

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30 July 2017

M Le Gall

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30 July 2017

F Viñals

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30 July 2017

E Gothié

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30 July 2017

D Roux

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30 July 2017

G Pagès

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30 July 2017

language of work or name

English

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publication date

1 October 2000

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30 July 2017

Biochemical Pharmacology

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30 July 2017

60

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30 July 2017

8

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30 July 2017

1171-1178

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What Is the Evidence That Tumors Are Angiogenesis Dependent?

30 July 2017

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Angiogenesis in cancer, vascular, rheumatoid and other disease

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Clinical importance of the determination of tumor angiogenesis in breast carcinoma: much more than a new prognostic tool

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Vascular endothelial growth factor is a secreted angiogenic mitogen

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Mechanisms of angiogenesis

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Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

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Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

7 January 2021

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Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

7 January 2021

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How MAP kinases are regulated

7 January 2021

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The MAPK signaling cascade

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Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo

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Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

7 January 2021

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Regulation of carbamoyl phosphate synthetase by MAP kinase

7 January 2021

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The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal

7 January 2021

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Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

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Inhibition of platelet-derived growth factor- and epidermal growth factor-mediated mitogenesis and signaling in 3T3 cells expressing delta Raf-1:ER, an estradiol-regulated form of Raf-1.

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Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway

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Interference with endogenous ras function inhibits cellular responses to wounding

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The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells

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p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells.

7 January 2021

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Stimulation of the mitogen-activated protein kinase via the A2A-adenosine receptor in primary human endothelial cells

7 January 2021

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Nitric oxide is an upstream signal of vascular endothelial growth factor-induced extracellular signal-regulated kinase1/2 activation in postcapillary endothelium

7 January 2021

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Confluence of vascular endothelial cells induces cell cycle exit by inhibiting p42/p44 mitogen-activated protein kinase activity

7 January 2021

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Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing

7 January 2021

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Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells

7 January 2021

1 reference

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Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia

7 January 2021

1 reference

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Transforming growth factor-alpha-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP-2-dependent DNA binding and transactivation.

7 January 2021

1 reference

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p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts

7 January 2021

1 reference

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Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia.

7 January 2021

1 reference

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

7 January 2021

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Purification and characterization of hypoxia-inducible factor 1

7 January 2021

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The hypoxic response: huffing and HIFing

7 January 2021

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Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

7 January 2021

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Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor

7 January 2021

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Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor

7 January 2021

1 reference

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Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

7 January 2021

1 reference

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Angiogenesis: how a tumor adapts to hypoxia

7 January 2021

1 reference

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

7 January 2021

1 reference

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Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

7 January 2021

1 reference

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Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

7 January 2021

1 reference

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

7 January 2021

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Mdm2 promotes the rapid degradation of p53

7 January 2021

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Regulation of p53 stability by Mdm2

7 January 2021

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

7 January 2021

1 reference

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p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900423-8

Effect of protein kinase and phosphatase inhibitors on expression of hypoxia-inducible factor 1.

7 January 2021

1 reference

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Hypoxia-inducible factor 1: master regulator of O2 homeostasis

7 January 2021

1 reference

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10.1016/S0006-2952(00)00423-8

7 January 2021

Identifiers

DOI

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30 July 2017

1 reference