Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation (Q34049636)

30 July 2017

title

Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation (English)

1 reference

30 July 2017

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4

Eugene B Chang

1 reference

30 July 2017

Harn Shiue

1

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30 July 2017

Mark W Musch

series ordinal

2

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30 July 2017

Yingmin Wang

series ordinal

3

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30 July 2017

Jerrold R Turner

series ordinal

5

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30 July 2017

language of work or name

English

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publication date

4 November 2004

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Journal of Biological Chemistry

30 July 2017

published in

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30 July 2017

volume

280

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30 July 2017

issue

2

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30 July 2017

page(s)

1688-1695

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describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1237052/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival.

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237052

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28 July 2018

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Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase

28 July 2018

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RhoA-dependent phosphorylation and relocalization of ERM proteins into apical membrane/actin protrusions in fibroblasts

28 July 2018

1 reference

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28 July 2018

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28 July 2018

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Carboxy-terminal vesicular stomatitis virus G protein-tagged intestinal Na+-dependent glucose cotransporter (SGLT1): maintenance of surface expression and global transport function with selective perturbation of transport kinetics and polarized expr

28 July 2018

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A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

28 July 2018

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Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237052

Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site

28 July 2018

1 reference

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Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

28 July 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409471200

Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409471200

Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409471200

Ezrin regulates NHE3 translocation and activation after Na+-glucose cotransport.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409471200

Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409471200

A dileucine motif targets the sulfate anion transporter sat-1 to the basolateral membrane in renal cell lines

21 January 2018

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Inhibition and redistribution of NHE3, the apical Na+/H+ exchanger, by Clostridium difficile toxin B.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409471200

Role of p38 MAPK and MAPKAPK-2 in angiotensin II-induced Akt activation in vascular smooth muscle cells

21 January 2018

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An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409471200

Differential effects of phosphatidylinositol 3-kinase inhibition on intracellular signals regulating GLUT4 translocation and glucose transport

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409471200

Lipid Raft targeting of the TC10 amino terminal domain is responsible for disruption of adipocyte cortical actin

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409471200

Requirement of the epidermal growth factor receptor in renal epithelial cell proliferation and migration

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237052

NHE3-dependent cytoplasmic alkalinization is triggered by Na(+)-glucose cotransport in intestinal epithelia

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237052

Phosphoinositide 3-kinase is required for insulin-induced but not for growth hormone- or hyperosmolarity-induced glucose uptake in 3T3-L1 adipocytes

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237052

Protein kinase C-theta phosphorylation of moesin in the actin-binding sequence

28 October 2018

1 reference

12 December 2020

RhoA and rho kinase regulate the epithelial Na+/H+ exchanger NHE3. Role of myosin light chain phosphorylation

1 reference

12 December 2020

Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly

1 reference

12 December 2020

The apical Na(+)/H(+) exchanger isoform NHE3 is regulated by the actin cytoskeleton

1 reference

12 December 2020

Soluble ezrin purified from placenta exists as stable monomers and elongated dimers with masked C-terminal ezrin-radixin-moesin association domains

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M409471200

1 reference

30 July 2017

1 reference

30 July 2017

1 reference