Dextrans for targeted and sustained delivery of therapeutic and imaging agents (Q34052939)

30 July 2017

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title

Dextrans for targeted and sustained delivery of therapeutic and imaging agents (English)

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ORCID Public Data File 2021

30 July 2017

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author name string

R Mehvar

series ordinal

1

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PubMed ID

11018543

30 July 2017

language of work or name

English

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publication date

1 October 2000

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Journal of Controlled Release

30 July 2017

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30 July 2017

69

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30 July 2017

1

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30 July 2017

1-25

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High-performance size-exclusion chromatographic procedure for the determination of fluoresceinyl isothiocyanate dextrans of various molecular masses in biological media

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Molecular-weight-dependent pharmacokinetics of fluorescein-labeled dextrans in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Human glomerular membrane porosity and filtration pressure: dextran clearance data analysed by theoretical models

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

THE INTRAVASCULAR PERSISTENCE OF DEXTRAN OF DIFFERENT MOLECULAR SIZES IN NORMAL HUMANS

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Disposition characteristics of macromolecules in tumor-bearing mice

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Permselectivity of the glomerular capillary wall to macromolecules. II. Experimental studies in rats using neutral dextran

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

The splitting of dextran and isomaltose by animal tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Biliary secretion of fluid-phase markers by the isolated perfused rat liver. Role of transcellular vesicular transport

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Molecular weight dependent tissue accumulation of dextrans: in vivo studies in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Polysaccharides as drug carriers: biodisposition of fluorescein-labeled dextrans in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Dose dependency of the kinetics of dextrans in rats: effects of molecular weight

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Hepatic disposition characteristics of electrically charged macromolecules in rat in vivo and in the perfused liver

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Demonstration of the receptor-mediated hepatic uptake of dextran in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Synthesis and pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Immobilization of enzymes on slowly soluble carriers

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Control of pharmaceutical properties of soybean trypsin inhibitor by conjugation with dextran. I: Synthesis and characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Higher Antitumor Efficacy of Daunomycin When Linked to Dextran: In Vivo and In Vitro Studies 2

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Chemical Coupling of Peptides and Proteins to Polysaccharides by Means of Cyanogen Halides

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Binding of Covalent Proteins to Polysaccharides by Cyanogen Bromide and Organic Cyanates. I. Preparation of Soluble Glycine-, Insulin- and Ampicillin-dextran

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Soluble dextran complexes of Kallikrein, Bradykinin and enzyme inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

The reaction of dextran carbonate with amino acids and polypeptides.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Comparison of efficacy, toxicity and pharmacokinetics of free adriamycin and adriamycin linked to oxidized dextran in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Phase I clinical and pharmacokinetic trial of dextran conjugated doxorubicin (AD-70, DOX-OXD).

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Tissue distribution of macromolecular conjugate, adriamycin linked to oxidized dextran, in rat and mouse bearing tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Cytotoxicity and DNA binding characteristics of dextran-conjugated doxorubicins.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Altered pharmacokinetic and tumour localization properties of Fab' fragments of a murine monoclonal anti-CEA antibody by covalent modification with low molecular weight dextran.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Comparative pharmacokinetic properties of murine monoclonal antibody A7 modified with neocarzinostatin, dextran and polyethylene glycol.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Soluble asparaginase-dextran conjugates show increased circulatory persistence and lowered antigen reactivity

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Covalent linkage of carboxypeptidase G2 to soluble dextrans--I. Properties of conjugates and effects on plasma persistence in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Covalent linkage of carboxypeptidase G2 to soluble dextrans--II. In vivo distribution and fate of conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Novel preparation of decylenediamine-dextran T70 and inhibitory activity toward dihydrofolate reductase of decylenediamine-dextran T70-methotrexate conjugate

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Preparation of dextran T70-methotrexate conjugate and dextran T70-mycophenolic acid conjugate, and in vitro effect of dextran T70-methotrexate on dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Mitomycin C-dextran conjugate: a novel high molecular weight pro-drug of mitomycin C

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Urinary excretion characteristics of a polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Absorption characteristics of macromolecular prodrugs of mitomycin C following intramuscular administration

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Disposition and tumor localization of mitomycin C-dextran conjugates in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Pharmacokinetic characteristics and therapeutic effects of mitomycin C-dextran conjugates after intratumoural injection

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Blood levels and serum protein binding of cis-platinum(II) complexed to carboxymethyl-dextran

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Synthesis and cytotoxic activity of dextran carrying cis-dichloro(cyclohexane-trans-l-1,2-diamine)platinum(II) complex

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

In vitro characteristics and in vivo plasma disposition of cisplatin conjugated with oxidized and dicarboxymethylated dextrans

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Development of intra-arterial hyperthermia using a dextran-magnetite complex

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Binding of epidermal growth factor-dextran conjugates to cultured glioma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Macromolecular prodrugs. XVI. Colon-targeted delivery--comparison of the rate of release of naproxen from dextran ester prodrugs in homogenates of various segments of the pig gastrointestinal (GI) tract

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Multiple oral administration of a ketoprofen-dextran ester prodrug in pigs: assessment of gastrointestinal bioavailability by deconvolution

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Glucocorticoid-dextran conjugates as potential prodrugs for colon-specific delivery: hydrolysis in rat gastrointestinal tract contents

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Glucocorticoid-dextran conjugates as potential prodrugs for colon-specific delivery: steady-state pharmacokinetics in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Intrahepatic delivery of glutathione by conjugation to dextran

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

A protective effect of glutathione-dextran macromolecular conjugates on acetaminophen-induced hepatotoxicity dependent on molecular size

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Pharmacokinetics of glutathione-dextran macromolecular conjugate in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Soluble dextran-hemoglobin complex as a potential blood substitute

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Blood replacement in dogs by dextran-hemoglobin

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Covalent fixation of hemoglobin to dextran phosphates decreases its oxygen affinity

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Rightshifted dextran-hemoglobin as blood substitute.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

The effects of stroma-free and dextran-conjugated hemoglobin on hemodynamics and carotid blood flow in hemorrhaged guinea pigs.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Assessment of Dextran 10-Benzene-Tetracarboxylate-Hemoglobin, An Oxygen Carrier, Using Guinea Pig Isolated Bowel Model

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Human hemoglobin conjugated to carboxylate dextran as a potential red blood cell substitute. II--Pharmacotoxicological evaluation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Biophysical basis of hypoxic radioprotection by deoxygenated dextran-hemoglobin

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Initial studies of hypoxic radioprotection by deoxygenated dextran-hemoglobin

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Studies on the Mode of Action of Insulin: Properties and Biological Activity of an Insulin-Dextran Complex

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Comparative effects of native insulin and insulin-dextran complexes on the metabolism of adipose tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Extending Insulin Action in Vivo by Conjugation to Carboxymethyl Dextran

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Therapeutic effects of superoxide dismutase derivatives modified with mono- or polysaccharides on hepatic injury induced by ischemia/reperfusion

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Increasing the plasma half-life of trichosanthin by coupling to dextran

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

The biological activities of trichosanthin after coupling to dextran

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Lowering of trichosanthin immunogenicity by site-specific coupling to dextran

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Biochemical and biopharmaceutical properties of macromolecular conjugates of uricase with dextran and polyethylene glycol

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Tissue Distribution of 111In-Labeled Uricase Conjugated with Charged Dextrans and Polyethylene Glycol

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Therapeutic efficacy of a polymyxin B-dextran 70 conjugate in experimental model of endotoxemia

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Polymyxin-dextran antiendotoxin pretreatment in an ovine model of normotensive sepsis.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Simultaneous analysis of dextran-methylprednisolone succinate, methylprednisolone succinate, and methylprednisolone by size-exclusion chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Kinetics of hydrolysis of dextran-methylprednisolone succinate, a macromolecular prodrug of methylprednisolone, in rat blood and liver lysosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Synthesis and pharmacokinetics of a novel macromolecular prodrug of Tacrolimus (FK506), FK506-dextran conjugate

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Leishmania donovani: Therapeutic and prophylactic action of antimony dextran glycoside (RL-712) in the golden hamster

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Pharmacokinetic and toxicological studies of antimony dextran glycoside (RL-712).

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Utilization of Iron Dextran in Recurrent Iron Deficiency Anaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Technetium-99m dextran: a promising new protein-losing enteropathy imaging agent

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Renal imaging with 99Tc(m)-dextran

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Scintigraphic diagnosis of gastrointestinal bleeding with 99Tcm-dextran

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Tc-99m dextran: a new and sensitive general purpose scintigraphic agent for diagnosing intestinal inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Evaluation of Gd-DTPA-labeled dextran as an intravascular MR contrast agent: imaging characteristics in normal rat tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Paramagnetic Dextrans as Magnetic Resonance Blood Pool Tracers

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Carboxymethyl-dextran-gadolinium-DTPA as a blood-pool contrast agent for magnetic resonance angiography. Experimental study in rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Polymeric conjugates of Gd(3+)-diethylenetriaminepentaacetic acid and dextran. 1. Synthesis, characterization, and paramagnetic properties

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Polymeric conjugates of Gd(3+)-diethylenetriaminepentaacetic acid and dextran. 2. Influence of spacer arm length and conjugate molecular mass on the paramagnetic properties and some biological parameters

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Controlled delivery of Gd-containing liposomes to lymph nodes: surface modification may enhance MRI contrast properties

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Macromolecular beta-adrenergic antagonists discriminating between receptor and antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Heparin coupled to albumin, dextran and ficoll: influence on blood coagulation and platelets, and in vivo duration

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Use of polysaccharides as drug carriers. Dextran and inulin derivatives of procainamide

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Enhanced intracellular stability of dextran-horse radish peroxidase conjugate: an approach to enzyme replacement therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Dextran modification of a Fab'--beta-lactamase conjugate modulated by variable pretreatment of Fab' with amine-blocking reagents.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Distribution model for the intact urokinase and urokinases modified by soluble macromolecules in rat and mouse bodies.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

Reduced immunogenicity of beta-lactoglobulin by conjugation with carboxymethyl dextran

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2800%2900302-3

7 January 2021

10.1016/S0168-3659(00)00302-3

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11018543