Intra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trials (Q34055991)

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English	Intra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trials	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

Intra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trials (English)

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Europe PubMed Central

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30 July 2017

Linda-Gail Bekker

4

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Linda-Gail Bekker

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Europe PubMed Central

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30 July 2017

Wendy A. Burgers

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Wendy A Burgers

2

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Eftyhia Vardas

11

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Clive M Gray

13

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Josephine H Cox

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Josephine H Cox

8

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Carolyn Williamson

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Carolyn Williamson

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30 July 2017

Heather B Jaspan

3

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Heather B Jaspan

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30 July 2017

author name string

Lycias Zembe

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30 July 2017

Helba Bredell

5

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Europe PubMed Central

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30 July 2017

Gwynneth Stevens

6

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30 July 2017

Jill Gilmour

7

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30 July 2017

Patricia Fast

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30 July 2017

Peter Hayes

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30 July 2017

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publication date

12 October 2011

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30 July 2017

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Europe PubMed Central

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30 July 2017

6

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Europe PubMed Central

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30 July 2017

10

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Europe PubMed Central

PubMed publication ID

30 July 2017

e26096

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Europe PubMed Central

PubMed publication ID

30 July 2017

copyright license

Creative Commons Attribution 4.0 International

12 October 2011

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April 2022 Public Data File from Crossref

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Mapping HIV-1 vaccine induced T-cell responses: bias towards less-conserved regions and potential impact on vaccine efficacy in the Step study

1 reference

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28 July 2018

Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China

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Constraints on HIV-1 diversity from protein structure

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HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition

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Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

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NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11

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CD8 T-cell recognition of multiple epitopes within specific Gag regions is associated with maintenance of a low steady-state viremia in human immunodeficiency virus type 1-seropositive patients

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Cross-clade reactivity of HIV-1-specific T-cell responses in HIV-1-infected individuals from Botswana and Cameroon.

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Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1

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Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes

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Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load

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Detection of high frequencies of HIV-1 cross-subtype reactive CD8 T lymphocytes in the peripheral blood of HIV-1-infected Kenyans

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Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences

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Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers

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Relative dominance of Gag p24-specific cytotoxic T lymphocytes is associated with human immunodeficiency virus control

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High degree of inter-clade cross-reactivity of HIV-1-specific T cell responses at the single peptide level.

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Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

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T cell responses in HIV type 1-infected adolescent minorities share similar epitope specificities with whites despite significant differences in HLA class I alleles

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Examining the independent binding assumption for binding of peptide epitopes to MHC-I molecules

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based on heuristic

inferred from PubMed ID database lookup

Binding of longer peptides to the H-2Kb heterodimer is restricted to peptides extended at their C terminus: refinement of the inherent MHC class I peptide binding criteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/22022524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level

1 reference

https://pubmed.ncbi.nlm.nih.gov/22022524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-clade immune responses to Gag p24 in patients infected with different HIV-1 subtypes and correlation with HLA class I and II alleles

1 reference

https://pubmed.ncbi.nlm.nih.gov/22022524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0026096

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

2011PLoSO...626096Z

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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