MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 (Q34056972)

30 July 2017

title

MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 (English)

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30 July 2017

2

Giovanna Poce

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30 July 2017

Silvia Buroni

4

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Claudio Battilocchio

Claudio Battilocchio

10

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Maria Rosalia Pasca

Maria Rosalia Pasca

5

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Mariangela Biava

Mariangela Biava

6

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Fabrizio Manetti

Fabrizio Manetti

15

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Eric Rubin

Eric J Rubin

18

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Thomas R Ioerger

13

Thomas R Ioerger

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30 July 2017

16

Maurizio Botta

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30 July 2017

Valentina La Rosa

1

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Julio Ortiz Canseco

3

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Ravikiran M Raju

7

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Giulio Cesare Porretta

8

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Salvatore Alfonso

9

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Babak Javid

11

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Flavia Sorrentino

12

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James C Sacchettini

14

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Alessandro De Logu

17

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Edda De Rossi

19

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30 July 2017

language of work or name

English

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publication date

24 October 2011

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Antimicrobial Agents and Chemotherapy

30 July 2017

published in

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30 July 2017

volume

56

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30 July 2017

issue

1

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30 July 2017

page(s)

324-331

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Target validation: linking target and chemical properties to desired product profile

30 July 2017

cites work

1 reference

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Discovery and characterization of a unique mycobacterial heme acquisition system

5 July 2018

1 reference

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Developing pyrrole-derived antimycobacterial agents: a rational lead optimization approach

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

New drugs and new regimens for the treatment of tuberculosis: review of the drug development pipeline and implications for national programmes

5 July 2018

1 reference

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Mycobacterium tuberculosis: drug resistance and future perspectives

5 July 2018

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Multidrug-resistant and extensively drug-resistant tuberculosis: a review

5 July 2018

1 reference

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Efflux pumps as antimicrobial resistance mechanisms

5 July 2018

1 reference

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Drugs for bad bugs: confronting the challenges of antibacterial discovery

5 July 2018

1 reference

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Contribution of the Mycobacterium tuberculosis MmpL protein family to virulence and drug resistance

5 July 2018

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Genetic studies on microbial cross resistance to toxic agents. I. Cross resistance of Escherichia coli to fifteen antibiotics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

BM 212 and its derivatives as a new class of antimycobacterial active agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

Construction of a family of Mycobacterium/Escherichia coli shuttle vectors derived from pAL5000 and pACYC184: their use for cloning an antibiotic-resistance gene from Mycobacterium fortuitum.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

A model recognition approach to the prediction of all-helical membrane protein structure and topology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

Genetic systems for mycobacteria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

Superinfection immunity of mycobacteriophage L5: applications for genetic transformation of mycobacteria

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256021

Preclinical testing of new drugs for tuberculosis: current challenges

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22024828

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.05270-11

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30 July 2017

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30 July 2017

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