Effect of therapeutic macromolecules in spheroids (Q34060938)

30 July 2017

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title

Effect of therapeutic macromolecules in spheroids (English)

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30 July 2017

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Fracasso G

1

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30 July 2017

Colombatti M

series ordinal

2

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30 July 2017

publication date

1 November 2000

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Critical Reviews in Oncology Hematology

30 July 2017

published in

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30 July 2017

volume

36

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30 July 2017

issue

2-3

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30 July 2017

page(s)

159-178

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Cell and environment interactions in tumor microregions: the multicell spheroid model

30 July 2017

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Use of multi-cell spheroids of ovarian carcinoma as an intraperitoneal radio-immunotherapy model: uptake, retention kinetics and dosimetric evaluation

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Radioimmunotherapy of prostatic adenocarcinomas: Effects of 131I‐labelled E4 antibodies on cells at different depth in DU 145 spheroids

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A tumour spheroid model for antibody-targeted therapy of micrometastases

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Targeting radiation to tumours

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7 January 2021

Damage to multicellular human H-2 glioma spheroids incubated with LAK cells: an ultrastructural study

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7 January 2021

Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

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7 January 2021

3-D coculture of hepatic sinusoidal cells with primary hepatocytes-design of an organotypical model

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Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumour biopsies in vitro

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7 January 2021

Effects of growth factors on a human glioma cell line during invasion into rat brain aggregates in culture

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7 January 2021

Leptomeningeal tissue: a barrier against brain tumor cell invasion

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7 January 2021

Brain-derived neurotrophic factor induces functional expression and phenotypic differentiation of cultured fetal neuropeptide Y-producing neurons.

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7 January 2021

Dynorphins modulate DNA synthesis in fetal brain cell aggregates

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7 January 2021

Thrombin stimulation of matrix fibronectin.

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Skin fibroblasts are the only source of nidogen during early basal lamina formation in vitro.

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7 January 2021

Characterization of morphology and cellular metabolism during the spheroid formation by fibroblasts

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7 January 2021

Formation of hair follicles from a single-cell suspension of embryonic rat skin by a two-step procedure in vitro

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7 January 2021

Contribution of ATP-sensitive potassium channels to the electrophysiological effects of adenosine in guinea-pig atrial cells

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7 January 2021

A review of the effects of three cardioactive agents on the electrical activity from embryonic chick heart cell aggregates: TTX, ACh, and E-4031.

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7 January 2021

Comparison of indapamide and hydrochlorothiazide on spontaneous contraction of cardiomyocytes in culture: the effect on alterations of extracellular calcium or potassium

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7 January 2021

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7 January 2021

A comparative study of effects of isoproterenol and dihydroouabain on calcium transients and contraction in cultured rat ventricular cells

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7 January 2021

Establishment in culture of pluripotential cells from mouse embryos

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7 January 2021

Evaluation of a novel in vitro assay for assessing drug penetration into avascular regions of tumours.

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7 January 2021

Three-dimensional cell culture induces novel proliferative and metabolic alterations associated with oncogenic transformation

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7 January 2021

A system for viably maintaining a stirred suspension of multicellular spheroids during NMR spectroscopy

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7 January 2021

Lipid metabolism in large T47D human breast cancer spheroids: 31P- and 13C-NMR studies of choline and ethanolamine uptake.

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7 January 2021

Proton NMR microscopy of multicellular tumor spheroid morphology

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7 January 2021

Delivery of novel therapeutic agents in tumors: physiological barriers and strategies

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7 January 2021

The pharmacology of monoclonal antibodies

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7 January 2021

The effect of antigen concentration, antibody valency and size, and tumor architecture on antibody binding in multicell spheroids

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7 January 2021

Homogeneous penetration but heterogeneous binding of antibodies to carcinoembryonic antigen in human colon carcinoma HT-29 spheroids.

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7 January 2021

The selection of antibodies for targeted therapy of small-cell lung cancer (SCLC) using a human tumour spheroid model to compare the uptake of cluster 1 and cluster w4 antibodies

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7 January 2021

Diffusion and binding of monoclonal antibody TNT-1 in multicellular tumor spheroids

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7 January 2021

Comparative targeting of human colon-carcinoma multicell spheroids using one- and two-step (bispecific antibody) techniques

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7 January 2021

Antibodies against metal chelates

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7 January 2021

Penetration and binding of monoclonal antibody in human osteosarcoma multicell spheroids. Comparison of confocal laser scanning microscopy and autoradiography

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7 January 2021

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7 January 2021

Phase I–II study of radiolabeled antibody integrated in the treatment of primary hepatic malignancies

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7 January 2021

The distribution of alternative agents for targeted radiotherapy within human neuroblastoma spheroids

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7 January 2021

Effects of 131I-labeled TNT-1 radioimmunotherapy on HT-29 human colon adenocarcinoma spheroids

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7 January 2021

Cell death induced by a 131I-labeled monoclonal antibody in ovarian cancer multicell spheroids

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7 January 2021

Comparisons of sectioned micro-TLD dose measurements with predicted dose from 131I-labeled antibody

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7 January 2021

SR-4233: a new bioreductive agent with high selective toxicity for hypoxic mammalian cells

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7 January 2021

The combined use of 131I-labeled antibody and the hypoxic cytotoxin SR 4233 in vitro and in vivo

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7 January 2021

Comparisons of the efficacy of 186Re- and 131I-labeled antibody in multicell spheroids

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https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900084-6

7 January 2021

Glycosphingolipids in cellular interaction, differentiation, and oncogenesis

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7 January 2021

Tumor Therapy by Immune Recruitment with Bispecific Antibodies

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7 January 2021

A phase I study of a HER2/neu bispecific antibody with granulocyte-colony-stimulating factor in patients with metastatic breast cancer that overexpresses HER2/neu

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7 January 2021

Colorectal carcinoma antigens detected by hybridoma antibodies

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7 January 2021

Phase I trial of a mouse monoclonal antibody against GD3 ganglioside in patients with melanoma: induction of inflammatory responses at tumor sites

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7 January 2021

Resistance of ovarian teratocarcinoma cell spheroids to complement-mediated lysis

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7 January 2021

Integrin expression on colorectal tumor cells growing as monolayers, as multicellular tumor spheroids, or in nude mice

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7 January 2021

Collagens, integrins and the mesenchymal drift in glioblastomas: A comparison of biopsy specimens, spheroid and early monolayer cultures

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7 January 2021

A novel monoclonal antibody, L1A3, is directed to the functional site of the alpha v integrin subunit

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7 January 2021

Stimulation of glioma-cell migration by laminin and inhibition by anti-alpha3 and anti-beta1 integrin antibodies

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7 January 2021

Apoptosis induced by inhibition of intercellular contact

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7 January 2021

Immunotoxins: an update

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7 January 2021

One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell

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7 January 2021

Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells

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7 January 2021

Ribosome-inactivating proteins up to date

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7 January 2021

Inhibition of Human Acute Lymphoblastic Leukemia Cells by Immunotoxins: Potentiation by Chloroquine

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7 January 2021

Carboxylic ionophores enhance the cytotoxic potency of ligand- and antibody-delivered ricin A chain

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7 January 2021

Sensitivity of human glioma cells to cytotoxic heteroconjugates.

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7 January 2021

Cytoreductive effects of anti-transferrin receptor immunotoxin in a multicellular tumor spheroid model

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7 January 2021

Mutations in diphtheria toxin separate binding from entry and amplify immunotoxin selectivity

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7 January 2021

Efficacy and selectivity of monoclonal-antibody-targeted drugs and free methotrexate in fluorescence-labelled mixed tumour-cell monolayer cultures and multicellular spheroids

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7 January 2021

Heterogeneous response of individual multicellular tumour spheroids to immunotoxins and ricin toxin

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7 January 2021

A non-parametric method for the analysis of experimental tumour growth data.

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7 January 2021

Penetration of anti-melanoma immunotoxin into multicellular tumor spheroids and cell kill effects

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7 January 2021

Effects of cellular pharmacology on drug distribution in tissues

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7 January 2021

In vitro inhibition of human glioblastoma cell line invasiveness by antisense uPA receptor

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7 January 2021

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900084-6

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7 January 2021

Response of multicellular tumor spheroids to liposomes containing TNF-alpha

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7 January 2021

Interaction of liposome-associated all-trans-retinoic acid with squamous carcinoma cells

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7 January 2021

Blockade of the galactose-binding sites of ricin by its linkage to antibody. Specific cytotoxic effects of the conjugates

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7 January 2021

Interleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion protein

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7 January 2021

Interleukin 2-diphtheria toxin fusion protein can abolish cell-mediated immunity in vivo

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7 January 2021

10.1016/S1040-8428(00)00084-6

Identifiers

DOI

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30 July 2017

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