Phosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channel (Q34062260)

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10 February 2020

title

Phosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channel (English)

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10 February 2020

1

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10 February 2020

Flavien Charpentier

6

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10 February 2020

Isabelle Baró

8

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10 February 2020

Gildas Loussouarn

9

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10 February 2020

author name string

Mohamed Yassine Amarouch

2

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10 February 2020

Jérôme Montnach

3

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10 February 2020

Julien Piron

4

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10 February 2020

Alain J Labro

5

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10 February 2020

Jean Mérot

7

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10 February 2020

language of work or name

English

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publication date

1 August 2010

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10 February 2020

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10 February 2020

volume

99

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10 February 2020

issue

4

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10 February 2020

page(s)

1110-1118

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Transfer of rolf S3-S4 linker to HERG eliminates activation gating but spares inactivation

10 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

A single charged voltage sensor is capable of gating the Shaker K+ channel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

PKC activation and PIP(2) depletion underlie biphasic regulation of IKs by Gq-coupled receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

Electrostatic interaction of internal Mg2+ with membrane PIP2 Seen with KCNQ K+ channels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

Phosphatidylinositol 4,5-bisphosphate interactions with the HERG K(+) channel.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

Structural requirements for differential sensitivity of KCNQ K+ channels to modulation by Ca2+/calmodulin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

Phosphatidylinositol-4,5-bisphosphate, PIP2, controls KCNQ1/KCNE1 voltage-gated potassium channels: a functional homology between voltage-gated and inward rectifier K+ channels.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

PIP(2) and proteins: interactions, organization, and information flow

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

The kinetic and physical basis of K(ATP) channel gating: toward a unified molecular understanding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

Pathways of HERG inactivation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

Regulation of cardiac Na+,Ca2+ exchange and KATP potassium channels by PIP2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

Giant excised cardiac sarcolemmal membrane patches: sodium and sodium-calcium exchange currents.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

Impaired KCNQ1-KCNE1 and phosphatidylinositol-4,5-bisphosphate interaction underlies the long QT syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

Characteristic interactions with phosphatidylinositol 4,5-bisphosphate determine regulation of kir channels by diverse modulators

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

HERG K(+) channel activity is regulated by changes in phosphatidyl inositol 4,5-bisphosphate

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

Assaying phosphatidylinositol bisphosphate regulation of potassium channels

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920645

MinK-KvLQT1 fusion proteins, evidence for multiple stoichiometries of the assembled IsK channel

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20712994

12 December 2020

inferred from PubMed ID database lookup

KCNQ1 K+ channel-mediated cardiac channelopathies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20712994

12 December 2020

inferred from PubMed ID database lookup

Cellular consequences of HERG mutations in the long QT syndrome: precursors to sudden cardiac death

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20712994

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.BPJ.2010.06.013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20712994%20AND%20SRC:MED&resulttype=core&format=json

release_rsr7jso6yvczzl7ws7pb7r5hwm

10 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rsr7jso6yvczzl7ws7pb7r5hwm

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20712994%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

20712994

1 reference