Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model. (Q34063140)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

0 references

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Jesús Prieto

9

1 reference

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5 January 2020

Hans Lassmann

13

1 reference

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5 January 2020

Maria G. Castro

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Jerzy Kupiec-Węgliński

11

object named as

Jerzy Kupiec-Weglinski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

author name string

Sumia Ali

1

1 reference

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5 January 2020

Gwendalyn D King

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Marianela Candolfi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Weidong Xiong

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Chunyan Liu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Mariana Puntel

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Queng Cheng

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Antoni Ribas

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Pedro R Lowenstein

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Nico van Rooijen

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

language of work or name

English

0 references

publication date

1 August 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

volume

65

1 reference

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5 January 2020

issue

16

1 reference

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5 January 2020

page(s)

7194-7204

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

Primary antitumor immune response mediated by CD4+ T cells

5 January 2020

cites work

1 reference

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CD4+ T cell-mediated antigen-specific immunotherapy in a mouse model of cervical cancer

5 July 2018

1 reference

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CD4+ T cells kill Id+ B-lymphoma cells: FasLigand-Fas interaction is dominant in vitro but is redundant in vivo.

5 July 2018

1 reference

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Inflammatory and anti-glioma effects of an adenovirus expressing human soluble Fms-like tyrosine kinase 3 ligand (hsFlt3L): treatment with hsFlt3L inhibits intracranial glioma progression.

5 July 2018

1 reference

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Tumor immunity meets autoimmunity: antigen levels and dendritic cell maturation.

5 July 2018

1 reference

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Vaccination of recurrent glioma patients with tumour lysate-pulsed dendritic cells elicits immune responses: results of a clinical phase I/II trial

5 July 2018

1 reference

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Clinical application of dendritic cells in cancer vaccination therapy

5 July 2018

1 reference

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Effects of IL-12 and IL-23 on antigen-presenting cells at the interface between innate and adaptive immunity

5 July 2018

1 reference

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Dendritic cells: controllers of the immune system and a new promise for immunotherapy

5 July 2018

1 reference

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Oncolytic viruses for the therapy of brain tumors and other solid malignancies a review

5 July 2018

1 reference

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Current and future strategies for the treatment of malignant brain tumors.

5 July 2018

1 reference

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Cytokines in the generation and maturation of dendritic cells: recent advances

5 July 2018

1 reference

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Vaccination with autologous tumour antigen-pulsed dendritic cells in advanced gynaecological malignancies: clinical and immunological evaluation of a phase I trial

5 July 2018

1 reference

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Treatment of malignant gliomas with a replicating adenoviral vector expressing herpes simplex virus-thymidine kinase

5 July 2018

1 reference

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Dendritic cells as vectors for therapy

5 July 2018

1 reference

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Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis

5 July 2018

1 reference

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Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses

5 July 2018

1 reference

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Incidence of brain tumours in two English counties: a population based study

5 July 2018

1 reference

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Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial

5 July 2018

1 reference

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Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma

5 July 2018

1 reference

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Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for ch

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Central nervous system toxicity of two adenoviral vectors encoding variants of the herpes simplex virus type 1 thymidine kinase: reduced cytotoxicity of a truncated HSV1-TK.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34(+) hematopoietic progenitor cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Instability of adenoviral vectors during transport and its implication for clinical studies

5 July 2018

1 reference

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Incidence studies of primary and secondary intracranial tumors: a systematic review of their methodology and results

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells.

5 July 2018

1 reference

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Ultrastructural and immunohistological evidence for dendritic-like cells within human choroid plexus epithelium.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified

5 July 2018

1 reference

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Human malignant brain tumor response to herpes simplex thymidine kinase (HSVtk)/ganciclovir gene therapy

5 July 2018

1 reference

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Supernatant rescue assay vs. polymerase chain reaction for detection of wild type adenovirus-contaminating recombinant adenovirus stocks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary human cells in the presence of adenovirus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Constitutive and enhanced expression from the CMV major IE promoter in a defective adenovirus vector

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Bystander effect-mediated gene therapy of gliomas using genetically engineered neural stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Regulation of dendritic cell expansion in aged athymic nude mice by FLT3 ligand.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Flt3 ligand preferentially increases the number of functionally active myeloid dendritic cells in the lungs of mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

The first 1000 dendritic cell vaccinees.

28 October 2018

1 reference

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Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

A pilot trial of tumor lysate-loaded dendritic cells for the treatment of metastatic renal cell carcinoma

28 October 2018

1 reference

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Allogeneic Dendritic Cells Fused with Tumor Cells: Preclinical Results and Outcome of a Clinical Phase I/II Trial in Patients with Metastatic Renal Cell Carcinoma

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Adenovirus-mediated herpes simplex virus thymidine kinase gene therapy in BT4C rat glioma model

28 October 2018

1 reference

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Double suicide gene therapy using a replication defective herpes simplex virus vector reveals reciprocal interference in a malignant glioma model

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Flt3 ligand and granulocyte-macrophage colony-stimulating factor preferentially expand and stimulate different dendritic and T-cell subsets.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Lethal hepatitis after gene transfer of IL-4 in the liver is independent of immune responses and dependent on apoptosis of hepatocytes: a rodent model of IL-4-induced hepatitis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Brain dendritic cells and macrophages/microglia in central nervous system inflammation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

In vivo gene transfer of CD40 ligand into colon cancer cells induces local production of cytokines and chemokines, tumor eradication and protective antitumor immunity

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a coadministered antigen: the role of nitric oxide

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Distribution and phenotype of dendritic cells and resident tissue macrophages in the dura mater, leptomeninges, and choroid plexus of the rat brain as demonstrated in wholemount preparations.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

There is a limited critical period for dopamine's effects on D1 receptor expression in the developing rat neostriatum.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Cell type-specific expression in brain cell cultures from a short human cytomegalovirus major immediate early promoter depends on whether it is inserted into herpesvirus or adenovirus vectors

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Selective destruction of gliomas in immunocompetent rats by thymidine kinase-defective herpes simplex virus type 1.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Immunosuppression and transforming growth factor-beta in glioblastoma. Preferential production of transforming growth factor-beta 2.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242178

Phenotype and functions of brain dendritic cells emerging during chronic infection of mice with Toxoplasma gondii

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16103070

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Durable complete clinical responses in a phase I/II trial using an autologous melanoma cell/dendritic cell vaccine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16103070

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

After initial setback, IL-12 regaining popularity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16103070

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-04-3434

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16103070%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference