Elucidation of IgH intronic enhancer functions via germ-line deletion (Q34063681)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Elucidation of IgH intronic enhancer functions via germ-line deletion (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Thomas Perlot

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Frederick W Alt

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Craig H Bassing

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Heikyung Suh

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

English

0 references

publication date

26 September 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

14362-14367

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

Immunoglobulin locus silencing and allelic exclusion

7 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Regulation of immunoglobulin heavy-chain gene rearrangements

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Unraveling V(D)J recombination; insights into gene regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

The generation of antibody diversity through somatic hypermutation and class switch recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

The mechanism and regulation of chromosomal V(D)J recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Mechanism and control of class-switch recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

The 3' IgH regulatory region: a complex structure in a search for a function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Regulation of V(D)J recombination by transcriptional promoters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Recombination and transcription of the endogenous Ig heavy chain locus is effected by the Ig heavy chain intronic enhancer core region in the absence of the matrix attachment regions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Reevaluation of 3'Ekappa function in stage- and lineage-specific rearrangement and somatic hypermutation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

The transcriptional promoter regulates hypermutation of the antibody heavy chain locus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Somatic hypermutation of an immunoglobulin mu heavy chain transgene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

A lymphocyte-specific enhancer in the mouse immunoglobulin kappa gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

C mu-containing transcripts initiate heterogeneously within the IgH enhancer region and contain a novel 5'-nontranslatable exon

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

The immunoglobulin kappa locus contains a second, stronger B-cell-specific enhancer which is located downstream of the constant region

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Distribution of mutations around rearranged heavy-chain antibody variable-region genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Coordination of immunoglobulin DJH transcription and D-to-JH rearrangement by promoter-enhancer approximation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1242331

Antisense intergenic transcription in V(D)J recombination

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507090102

Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507090102

Comparison of somatic mutation frequency among immunoglobulin genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507090102

The 5' hypermutation boundary of kappa chains is independent of local and neighbouring sequences and related to the distance from the initiation of transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507090102

An expressed neo(r) cassette provides required functions of the 1gamma2b exon for class switching.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0507090102

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

21 January 2018

1 reference

12 December 2020

The Ig(kappa) enhancer influences the ratio of Ig(kappa) versus Ig(lambda) B lymphocytes

1 reference

12 December 2020

The Ig heavy chain intronic enhancer core region is necessary and sufficient to promote efficient class switch recombination

1 reference

12 December 2020

A pivotal role for DNase I-sensitive regions 3b and/or 4 in the induction of somatic hypermutation of IgH genes

1 reference

12 December 2020

Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination

1 reference

12 December 2020

The influence of transcriptional orientation on endogenous switch region function

1 reference

12 December 2020

The immunoglobulin heavy-chain locus hs3b and hs4 3' enhancers are dispensable for VDJ assembly and somatic hypermutation

1 reference

12 December 2020

Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer

1 reference

12 December 2020

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

12 December 2020

A class switch control region at the 3′ end of the immunoglobulin heavy chain locus

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0507090102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186486%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

16186486

1 reference