Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo (Q34063772)

30 July 2017

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo (English)

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30 July 2017

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4

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30 July 2017

Borchelt DR

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30 July 2017

Thinakaran G

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30 July 2017

Eckman CB

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30 July 2017

Davenport F

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30 July 2017

Ratovitsky T

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30 July 2017

Prada CM

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30 July 2017

Kim G

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30 July 2017

Seekins S

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30 July 2017

Yager D

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30 July 2017

Slunt HH

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30 July 2017

Wang R

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30 July 2017

Seeger M

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30 July 2017

Levey AI

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30 July 2017

Gandy SE

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30 July 2017

Copeland NG

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30 July 2017

Jenkins NA

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30 July 2017

Price DL

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30 July 2017

Younkin SG

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30 July 2017

Sisodia SS

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30 July 2017

language of work or name

English

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publication date

1 November 1996

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30 July 2017

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17

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30 July 2017

1005-1013

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30 July 2017

5

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The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Mutation analysis of presenillin 1 gene in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

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https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Mutations of the presenilin I gene in families with early-onset Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Familial Alzheimer's disease associated with S182 codon 286 mutation

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https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

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https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3.

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https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Quantitative analysis of senile plaques in Alzheimer disease: observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome).

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Amyloid beta protein (A beta) deposition: A beta 42(43) precedes A beta 40 in Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

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https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

A familial Alzheimer's disease locus on chromosome 1.

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https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Mis-sense mutation Val&rarr;Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Genetic dissection of Alzheimer disease, a heterogeneous disorder

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https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Nucleotide sequence of the chromosome 14-encodedS182cDNA and revised secondary structure prediction

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

Familial Alzheimer's chromosome 14 mutations.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2980230-5

7 January 2021

10.1016/S0896-6273(00)80230-5

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DOI

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30 July 2017

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