Insulin receptor antibody-sulfamidase fusion protein penetrates the primate blood-brain barrier and reduces glycosoaminoglycans in Sanfilippo type A cells (Q34065044)

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English	Insulin receptor antibody-sulfamidase fusion protein penetrates the primate blood-brain barrier and reduces glycosoaminoglycans in Sanfilippo type A cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Insulin receptor antibody-sulfamidase fusion protein penetrates the primate blood-brain barrier and reduces glycosoaminoglycans in Sanfilippo type A cells (English)

1 reference

Europe PubMed Central

30 July 2017

0 references

blood–brain barrier

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

William M Pardridge

4

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Europe PubMed Central

30 July 2017

1

object named as

Ruben J Boado

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Europe PubMed Central

30 July 2017

author name string

Jeff Zhiqiang Lu

2

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Europe PubMed Central

30 July 2017

Eric Ka-Wai Hui

3

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Europe PubMed Central

30 July 2017

language of work or name

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publication date

26 June 2014

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Europe PubMed Central

30 July 2017

Molecular Pharmaceutics

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Europe PubMed Central

30 July 2017

11

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Europe PubMed Central

30 July 2017

2928-2934

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Europe PubMed Central

30 July 2017

8

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Europe PubMed Central

30 July 2017

Pharmacokinetics and brain uptake in the rhesus monkey of a fusion protein of arylsulfatase a and a monoclonal antibody against the human insulin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

Reengineering biopharmaceuticals for targeted delivery across the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

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Impact of high-dose, chemically modified sulfamidase on pathology in a murine model of MPS IIIA.

1 reference

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Expression in CHO cells and pharmacokinetics and brain uptake in the Rhesus monkey of an IgG-iduronate-2-sulfatase fusion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

Secondary storage of dermatan sulfate in Sanfilippo disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

Genetic engineering of IgG-glucuronidase fusion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

Comparison of blood-brain barrier transport of glial-derived neurotrophic factor (GDNF) and an IgG-GDNF fusion protein in the rhesus monkey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

Mannose 6-phosphate receptor-mediated transport of sulfamidase across the blood-brain barrier in the newborn mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

Sanfilippo syndrome: a mini-review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

SUMF1 enhances sulfatase activities in vivo in five sulfatase deficiencies

1 reference

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5 July 2018

Humanization of anti-human insulin receptor antibody for drug targeting across the human blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

Expression and functional characterization of human mutant sulfamidase in insect cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

Cloning of the sulphamidase gene and identification of mutations in Sanfilippo A syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

5 July 2018

Blood-brain barrier molecular trojan horse enables imaging of brain uptake of radioiodinated recombinant protein in the rhesus monkey.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

28 October 2018

Mucopolysaccharidosis type IIIA: clinical spectrum and genotype-phenotype correlations

1 reference

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28 October 2018

Murine model (Galns(tm(C76S)slu)) of MPS IVA with missense mutation at the active site cysteine conserved among sulfatase proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

28 October 2018

The effect of elevated plasma phenylalanine levels on protein synthesis rates in adult rat brain

1 reference

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28 October 2018

Drug transport across the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4137762

28 October 2018

A fluorimetric enzyme assay for the diagnosis of Sanfilippo disease type A (MPS IIIA)

1 reference

https://pubmed.ncbi.nlm.nih.gov/24949884

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracisternal enzyme replacement therapy in lysosomal storage diseases: routes of absorption into brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/24949884

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/MP500258P

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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