Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling. (Q34067821)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20616078%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling (English)

1 reference

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7 February 2020

1 reference

1

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7 February 2020

Forest M. White

5

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7 February 2020

Douglas A. Lauffenburger

6

object named as

Douglas A Lauffenburger

1 reference

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7 February 2020

author name string

Jason R Neil

2

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7 February 2020

Sivan Abramovitch

3

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7 February 2020

Yosef Yarden

4

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7 February 2020

K Dane Wittrup

7

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7 February 2020

language of work or name

English

0 references

publication date

7 July 2010

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

7 February 2020

published in

1 reference

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7 February 2020

volume

107

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7 February 2020

issue

30

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7 February 2020

page(s)

13252-13257

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Sym004: a novel synergistic anti-epidermal growth factor receptor antibody mixture with superior anticancer efficacy.

7 February 2020

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5 July 2018

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Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis

5 July 2018

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Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules

5 July 2018

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Directional persistence of EGF-induced cell migration is associated with stabilization of lamellipodial protrusions

5 July 2018

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Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapy

5 July 2018

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Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin

5 July 2018

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Fine epitope mapping of anti-epidermal growth factor receptor antibodies through random mutagenesis and yeast surface display

5 July 2018

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Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer

5 July 2018

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Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases

5 July 2018

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Developing inhibitors of the epidermal growth factor receptor for cancer treatment.

5 July 2018

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5 July 2018

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Epidermal growth factor receptor: mechanisms of activation and signalling.

5 July 2018

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EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

5 July 2018

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Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

5 July 2018

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Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Cycloheximide production by Streptomyces griseus: alleviation of end-product inhibition by dialysis-extraction fermentation

5 July 2018

1 reference

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Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

5 July 2018

1 reference

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Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity.

21 January 2018

1 reference

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Intracellular receptor/ligand sorting based on endosomal retention components.

21 January 2018

1 reference

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Engineering dynamics of growth factors and other therapeutic ligands

21 January 2018

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Autophosphorylation and protein kinase C phosphorylation of the epidermal growth factor receptor. Effect on tyrosine kinase activity and ligand binding affinity

21 January 2018

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Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

28 October 2018

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21 January 2018

Identifiers

DOI

10.1073/PNAS.0913476107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20616078%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

0 references

1 reference

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7 February 2020

1 reference