BBB transport and P-glycoprotein functionality using MDR1A (-/-) and wild-type mice. Total brain versus microdialysis concentration profiles of rhodamine-123. (Q34067977)

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English	BBB transport and P-glycoprotein functionality using MDR1A (-/-) and wild-type mice. Total brain versus microdialysis concentration profiles of rhodamine-123.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

BBB transport and P-glycoprotein functionality using MDR1A (-/-) and wild-type mice. Total brain versus microdialysis concentration profiles of rhodamine-123. (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

de Lange EC

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

de Bock G

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

Schinkel AH

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

de Boer AG

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Breimer DD

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

publication date

1 November 1998

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Europe PubMed Central

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30 July 2017

Pharmaceutical Research

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Europe PubMed Central

PubMed publication ID

30 July 2017

15

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Europe PubMed Central

PubMed publication ID

30 July 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1657-1665

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Europe PubMed Central

PubMed publication ID

30 July 2017

Multidrug resistance mediated by P-glycoproteins

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https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

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Brain uptake and anticancer activities of vincristine and vinblastine are restricted by their low cerebrovascular permeability and binding to plasma constituents in rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

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Biosynthesis, processing and half-life of P-glycoprotein in a human multidrug-resistant KB cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

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Exploring multidrug resistance using rhodamine 123.

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https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

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The use of intracerebral microdialysis to determine changes in blood-brain barrier transport characteristics.

1 reference

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Ionic composition of microdialysis perfusing solution alters the pharmacological responsiveness and basal outflow of striatal dopamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

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Repeated microdialysis perfusions: periprobe tissue reactions and BBB permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

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Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

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Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

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The use of intracerebral microdialysis for the determination of pharmacokinetic profiles of anticancer drugs in tumor-bearing rat brain

1 reference

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Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

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Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes

1 reference

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12 December 2020

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Effect of the p-glycoprotein inhibitor, cyclosporin A, on the distribution of rhodamine-123 to the brain: an in vivo microdialysis study in freely moving rats

1 reference

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12 December 2020

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Progesterone and its metabolites: the potent inhibitors of the transporting activity of P-glycoprotein in the adrenal gland

1 reference

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Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

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P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

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Application of intracerebral microdialysis to study regional distribution kinetics of drugs in rat brain

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Isolation and expression of a complementary DNA that confers multidrug resistance

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12 December 2020

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Evidence of post-translational regulation of P-glycoprotein associated with the expression of a distinctive multiple drug-resistant phenotype in Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

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Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

based on heuristic

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Critical factors of intracerebral microdialysis as a technique to determine the pharmacokinetics of drugs in rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

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based on heuristic

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Protein kinase C phosphorylates P-glycoprotein in multidrug resistant human KB carcinoma cells.

1 reference

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Differential modulation of P-glycoprotein transport by protein kinase inhibition

1 reference

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Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro

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A microdialysis method allowing characterization of intercellular water space in humans

1 reference

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Functional involvement of P-glycoprotein in blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

based on heuristic

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Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1 reference

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Characterization of an "in vitro" blood-brain barrier: effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

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Specialized localization of P-glycoprotein recognized by MRK 16 monoclonal antibody in endothelial cells of the brain and the spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

based on heuristic

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Use of fluorescent dyes as molecular probes for the study of multidrug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

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Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9833984

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

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12 December 2020

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Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability

1 reference

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Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone

1 reference

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Multidrug resistance gene (MDR1) expression in human brain tumors

1 reference

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Identifiers

10.1023/A:1011988024295

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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