Reovirus induction of and sensitivity to beta interferon in cardiac myocyte cultures correlate with induction of myocarditis and are determined by viral core proteins. (Q34069681)

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English	Reovirus induction of and sensitivity to beta interferon in cardiac myocyte cultures correlate with induction of myocarditis and are determined by viral core proteins.	scientific article

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8 November 2019

Reovirus induction of and sensitivity to beta interferon in cardiac myocyte cultures correlate with induction of myocarditis and are determined by viral core proteins (English)

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8 November 2019

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B Sherry

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8 November 2019

J Torres

2

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8 November 2019

M A Blum

3

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1 February 1998

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8 November 2019

Journal of Virology

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8 November 2019

72

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8 November 2019

2

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8 November 2019

1314-1323

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8 November 2019

COXSACKIE VIRUS B3 MYOCARDITIS IN MICE. AN ELECTRON MICROSCOPIC, IMMUNOFLUORESCENT AND VIRUS-ASSAY STUDY

1 reference

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5 July 2018

The reovirus protein mu2, encoded by the M1 gene, is an RNA-binding protein

1 reference

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5 July 2018

Core protein mu2 is a second determinant of nucleoside triphosphatase activities by reovirus cores

1 reference

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Preferential translation of reovirus mRNA by a sigma3-dependent mechanism

1 reference

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Reovirus-induced apoptosis of MDCK cells is not linked to viral yield and is blocked by Bcl-2.

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Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis

1 reference

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Double-stranded RNA is a trigger for apoptosis in vaccinia virus-infected cells.

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The pathogenesis of postinfectious myocarditis

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Reovirus-induced acute myocarditis in mice correlates with viral RNA synthesis rather than generation of infectious virus in cardiac myocytes.

1 reference

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Identification and characterization of a double-stranded RNA- reovirus temperature-sensitive mutant defective in minor core protein mu2

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When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA.

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

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The M1 gene is associated with differences in the temperature optimum of the transcriptase activity in reovirus core particles

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Reovirus protein lambda 3 is a poly(C)-dependent poly(G) polymerase

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Cytopathogenic effect in cardiac myocytes but not in cardiac fibroblasts is correlated with reovirus-induced acute myocarditis.

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Lymphocytes protect against and are not required for reovirus-induced myocarditis.

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Early steps in reovirus infection are associated with dramatic changes in supramolecular structure and protein conformation: analysis of virions and subviral particles by cryoelectron microscopy and image reconstruction

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Viral infection and the pathogenesis of dilated cardiomyopathy

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The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans

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Functional role of type I and type II interferons in antiviral defense

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5 July 2018

Multiple viral core proteins are determinants of reovirus-induced acute myocarditis.

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Coxsackievirus B3 infection leads to cell death of cardiac myocytes

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Antiviral protection by vesicular stomatitis virus-specific antibodies in alpha/beta interferon receptor-deficient mice.

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A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators

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Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene.

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Activation and characterization of the reovirus transcriptase: genetic analysis

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Cytoplasmic activation of human nuclear genes in stable heterocaryons

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Viral myocarditis. A review

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Synthesis of (2'-5')oligoadenylate and activation of an endoribonuclease in interferon-treated HeLa cells infected with reovirus

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Reovirus guanylyltransferase is L2 gene product lambda 2.

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5 July 2018

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Derivation and characterization of an efficiently myocarditic reovirus variant.

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Inhibitory activity for the interferon-induced protein kinase is associated with the reovirus serotype 1 sigma 3 protein

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The three-dimensional structure of reovirus obtained by cryo-electron microscopy

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The Lang strain of reovirus serotype 1 and the Dearing strain of reovirus serotype 3 differ in their sensitivities to beta interferon

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5 July 2018

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5 July 2018

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5 July 2018

REOVIRUS MYOCARDITIS IN MICE: AN ELECTRON MICROSCOPIC, IMMUNOFLUORESCENT, AND VIRUS ASSAY STUDY.

1 reference

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

Mechanism of interferon action. Activation of the human P1/eIF-2 alpha protein kinase by individual reovirus s-class mRNAs: s1 mRNA is a potent activator relative to s4 mRNA

1 reference

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Enteroviral infection of mice with severe combined immunodeficiency. Evidence for direct viral pathogenesis of myocardial injury

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https://pubmed.ncbi.nlm.nih.gov/9445032

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Acute myocarditis. Rapid diagnosis by PCR in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/9445032

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Double-stranded RNA-dependent protein kinase (PKR) is regulated by reovirus structural proteins

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1 reference

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12 December 2020

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The induction of interferon by temperature-sensitive mutants of reovirus, UV-irradiated reovirus, and subviral reovirus particles

1 reference

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based on heuristic

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Interferon action against reovirus: activation of interferon-induced protein kinase in mouse L929 cells upon reovirus infection

1 reference

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12 December 2020

based on heuristic

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Mechanism of interferon action. Kinetics of decay of the antiviral state and protein phosphorylation in mouse fibroblasts treated with natural and cloned interferons

1 reference

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1 reference

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inferred from PubMed ID database lookup

Inhibition of protein synthesis in reovirus-infected HeLa cells with elevated levels of interferon-induced protein kinase activity

1 reference

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12 December 2020

based on heuristic

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Mechanism of interferon action. Effect of double-stranded RNA and the 5'-O-monophosphate form of 2',5'-oligoadenylate on the inhibition of reovirus mRNA translation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9445032

12 December 2020

based on heuristic

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Mechanism of interferon action. Increased phosphorylation of protein synthesis initiation factor eIF-2 alpha in interferon-treated, reovirus-infected mouse L929 fibroblasts in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9445032

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of an antiviral state by interferon in the absence of elevated levels of 2,5-oligo(A) synthetase and eIF-2 kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9445032

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Identifiers

10.1128/JVI.72.2.1314-1323.1998

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1 reference

Europe PubMed Central

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8 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9445032%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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