The humanized NOD/SCID mouse as a preclinical model to study the fate of encapsulated human islets (Q34072336)

30 July 2017

title

The humanized NOD/SCID mouse as a preclinical model to study the fate of encapsulated human islets (English)

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30 July 2017

author name string

Vijayaganapathy Vaithilingam

1

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30 July 2017

Jose Oberholzer

2

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30 July 2017

Gilles J Guillemin

3

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30 July 2017

Bernard E Tuch

4

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30 July 2017

language of work or name

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10 May 2010

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The review of diabetic studies : RDS

30 July 2017

published in

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30 July 2017

volume

7

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30 July 2017

issue

1

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30 July 2017

page(s)

62-73

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Safety and viability of microencapsulated human islets transplanted into diabetic humans

30 July 2017

cites work

1 reference

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Human and rodent pancreatic beta-cells express IL-4 receptors and IL-4 protects against beta-cell apoptosis by activation of the PI3K and JAK/STAT pathways

5 July 2018

1 reference

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Encapsulation of human islets in novel inhomogeneous alginate-ca2+/ba2+ microbeads: in vitro and in vivo function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923381

Immunoglobulin-like transcript 3-Fc suppresses T-cell responses to allogeneic human islet transplants in hu-NOD/SCID mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923381

A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.

5 July 2018

1 reference

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An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells.

5 July 2018

1 reference

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Causes of limited survival of microencapsulated pancreatic islet grafts.

5 July 2018

1 reference

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Interleukin-10 and related cytokines and receptors

5 July 2018

1 reference

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Blocking the monocyte chemoattractant protein-1/CCR2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependent mechanism

5 July 2018

1 reference

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Chemokines in islet allograft rejection

5 July 2018

1 reference

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Association between macrophage activation and function of micro-encapsulated rat islets

5 July 2018

1 reference

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Decreased alloreactivity to human islets secreting recombinant viral interleukin 10.

5 July 2018

1 reference

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Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923381

Islet cell transplantation

5 July 2018

1 reference

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Viral IL-10 gene transfer prolongs rat islet allograft survival

28 October 2018

1 reference

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Interaction between pro-inflammatory and anti-inflammatory cytokines in insulin-producing cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923381

Microencapsulated pancreatic islet allografts into nonimmunosuppressed patients with type 1 diabetes: first two cases

28 October 2018

1 reference

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Role of donor-derived monocyte chemoattractant protein-1 in murine islet transplantation.

28 October 2018

1 reference

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Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice

28 October 2018

1 reference

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IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2923381

Human pancreatic islets produce and secrete MCP-1/CCL2: relevance in human islet transplantation

28 October 2018

1 reference

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Immunotherapy of spontaneous type 1 diabetes in nonobese diabetic mice by systemic interleukin-4 treatment employing adenovirus vector-mediated gene transfer

28 October 2018

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Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes.

28 October 2018

1 reference

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Conditions that enable human hematopoietic stem cell engraftment in all NOD-SCID mice

28 October 2018

1 reference

12 December 2020

Genetic deletion of chemokine receptor CXCR3 or antibody blockade of its ligand IP-10 modulates posttransplantation graft-site lymphocytic infiltrates and prolongs functional graft survival in pancreatic islet allograft recipients

1 reference

12 December 2020

Cytotoxic effects of cytokines on human pancreatic islet cells in monolayer culture

1 reference

12 December 2020

Transfer of genes for IL-10 and TGF-beta to isolated human pancreatic islets

1 reference

12 December 2020

Why do microencapsulated islet grafts fail in the absence of fibrotic overgrowth?

1 reference

12 December 2020

Differentiation of transplanted microencapsulated fetal pancreatic cells

1 reference

12 December 2020

Reduced immunogenicity of first-trimester human fetal pancreas

1 reference

12 December 2020

Allograft-specific cytokine profiles associate with clinical outcome after islet cell transplantation

1 reference

12 December 2020

Identifiers

DOI

10.1900/RDS.2010.7.62

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30 July 2017

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30 July 2017

1 reference