CTLA4-Ig: a novel immunosuppressive agent (Q34075083)

30 July 2017

1 reference

title

CTLA4-Ig: a novel immunosuppressive agent (English)

1 reference

30 July 2017

N Najafian

1

1 reference

PubMed ID

11060799

30 July 2017

M H Sayegh

series ordinal

2

1 reference

PubMed ID

11060799

30 July 2017

language of work or name

English

0 references

publication date

1 September 2000

1 reference

Expert Opinion on Investigational Drugs

30 July 2017

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30 July 2017

9

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30 July 2017

9

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30 July 2017

2147-2157

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Molecular mechanisms of action of new xenobiotic immunosuppressive drugs: tacrolimus (FK506), sirolimus (rapamycin), mycophenolate mofetil and leflunomide

30 July 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

The mechanism of action of cyclosporin A and FK506

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Chronic allograft failure: the clinical problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

The role of the CD28 receptor during T cell responses to antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

The B7 and CD28 receptor families

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

CTLA-4 is a second receptor for the B cell activation antigen B7

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

CTLA-4 can function as a negative regulator of T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Homeostasis and self-tolerance in the immune system: turning lymphocytes off.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

CD28/B7 system of T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

CD80 costimulation is essential for the induction of airway eosinophilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Treatment of murine lupus with CTLA4Ig

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Late blockade of T cell costimulation interrupts progression of experimental chronic allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Blockade of multiple costimulatory receptors induces hyporesponsiveness: inhibition of CD2 plus CD28 pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Induction of tolerance to small bowel allografts in high-responder rats by combining anti-CD4 with CTLA4Ig

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Transplantation of anergic histoincompatible bone marrow allografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.9.2147

10.1517/13543784.9.9.2147

21 January 2018

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11060799