Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease (Q34076863)

30 July 2017

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title

Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease (English)

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30 July 2017

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Praticò D

1

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PubMed ID

11063960

30 July 2017

Delanty N

series ordinal

2

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PubMed ID

11063960

30 July 2017

language of work or name

English

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publication date

1 November 2000

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American Journal of Medicine

30 July 2017

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30 July 2017

109

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30 July 2017

577-585

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30 July 2017

7

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30 July 2017

Evaluation of dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Treatment of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Molecular basis of the neurodegenerative disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

A model for susceptibility polymorphisms for complex diseases: apolipoprotein E and Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Early diagnosis and the clinical genetics of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Alzheimer's disease: genotypes, phenotypes, and treatments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Herpes simplex virus type 1 in brain and risk of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Abnormal function of potassium channels in platelets of patients with Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Oxidative injury in the nervous system.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Oxidative damage in neurodegenerative disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Free radicals, antioxidants, and human disease: curiosity, cause, or consequence?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Antioxidants, oxidative stress, and degenerative neurological disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Free radical theory of aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Oxidants, antioxidants, and the degenerative diseases of aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Aging, energy, and oxidative stress in neurodegenerative diseases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Aging and superoxide dismutase activity in cerebrospinal fluid.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Cardiovascular factors in Alzheimer's disease.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Traumatic brain injury and time to onset of Alzheimer's disease: a population-based study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

The influence of smoking on the risk of Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Risk of dementia among persons with diabetes mellitus: a population-based cohort study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Oxidative stress in closed-head injury: brain antioxidant capacity as an indicator of functional outcome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Modulation of oxidant stress in vivo in chronic cigarette smokers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Aging and high concentrations of glucose potentiate injury to mitochondrial DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Measurement of lipid peroxidation

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

7 January 2021

Autopsy samples of Alzheimer's cortex show increased peroxidation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Evidence of an oxidative challenge in the Alzheimer's brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Brain membrane fluidity and lipid peroxidation in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Selective increase in lipid peroxidation in the inferior temporal cortex in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Increased susceptibility of Alzheimer's disease temporal cortex to oxygen free radical-mediated processes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Assay of malondialdehyde in biological fluids by gas chromatography-mass spectrometry.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Evidence against the involvement of reactive oxygen species in the pathogenesis of neuronal death in down's syndrome and Alzheimer's Disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

F(2)-isoprostanes: sensitive and specific non-invasive indices of lipid peroxidation in vivo

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Cerebrospinal fluid F2-isoprostane levels are increased in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

The magnitude of brain lipid peroxidation correlates with the extent of degeneration but not with density of neuritic plaques or neurofibrillary tangles or with APOE genotype in Alzheimer's disease patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Formation of isoprostane-like compounds (neuroprostanes) in vivo from docosahexaenoic acid.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

F4-isoprostanes as specific marker of docosahexaenoic acid peroxidation in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Distribution of reducible 4-hydroxynonenal adduct immunoreactivity in Alzheimer disease is associated with APOE genotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Lipid peroxidation and free radical scavengers in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Evaluation of serum-lipid-related cardiovascular risk factors in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

No evidence for systemic oxidant stress in Parkinson's or Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Platelet and erythrocyte membrane changes in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Platelet membrane fluidity and plasma malondialdehyde levels in Alzheimer's demented patients with and without family history of dementia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Increased CSF F2-isoprostane concentration in probable AD.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Plasma levels of 8-epiPGF2alpha, an in vivo marker of oxidative stress, are not affected by aging or Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Oxidative damage to proteins: spectrophotometric method for carbonyl assay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Oxidative damage in Alzheimer's.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Widespread peroxynitrite-mediated damage in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Age-dependent accumulation of alkali-labile sites in DNA of post-mitotic but not in that of mitotic rat liver cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Assays for 8-hydroxy-2′-deoxyguanosine: A biomarker of in vivo oxidative DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Increased levels of DNA breaks in cerebral cortex of Alzheimer's disease patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

8OHdG levels in brain do not indicate oxidative DNA damage in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Increased nuclear DNA oxidation in the brain in Alzheimer's disease.

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

7 January 2021

Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF.

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Oxidative damage to DNA in lymphocytes from AD patients.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Nonenzymatic browning in vivo: possible process for aging of long-lived proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Radical AGEing in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Advanced glycation end products contribute to amyloidosis in Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Advanced Maillard reaction end products are associated with Alzheimer disease pathology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Altered glycosylation pattern of proteins in Alzheimer disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Progress toward valid transgenic mouse models for Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Alzheimer disease: mouse models pave the way for therapeutic opportunities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Antioxidant therapy in neurologic disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Ginkgo biloba extract protects brain neurons against oxidative stress induced by hydrogen peroxide.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Vitamin E protects nerve cells from amyloid beta protein toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Involvement of Oxidative Stress on the Impairment of Energy Metabolism Induced by Aβ Peptides on PC12 Cells: Protection by Antioxidants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Alzheimer beta protein mediated oxidative damage of mitochondrial DNA: prevention by melatonin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Protective effects of idebenone and alpha-tocopherol on beta-amyloid-(1-42)-induced learning and memory deficits in rats: implication of oxidative stress in beta-amyloid-induced neurotoxicity in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Alpha-tocopherol and Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Vitamin E and Alzheimer disease: the basis for additional clinical trials

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

Sustained efficacy and safety of idebenone in the treatment of Alzheimer's disease: update on a 2-year double-blind multicentre study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

7 January 2021

4-hydroxy-2-nonenal pyrrole adducts in human neurodegenerative disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2800%2900547-7

7 January 2021

10.1016/S0002-9343(00)00547-7

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11063960