Hepsin cooperates with MYC in the progression of adenocarcinoma in a prostate cancer mouse model. (Q34078067)

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12 February 2020

title

Hepsin cooperates with MYC in the progression of adenocarcinoma in a prostate cancer mouse model (English)

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12 February 2020

1 reference

1 reference

7

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12 February 2020

author name string

Srinivas Nandana

1

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12 February 2020

Katharine Ellwood-Yen

2

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12 February 2020

Charles Sawyers

3

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12 February 2020

Marcia Wills

4

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12 February 2020

Brandy Weidow

5

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12 February 2020

Thomas Case

6

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12 February 2020

Robert Matusik

8

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12 February 2020

publication date

1 May 2010

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12 February 2020

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12 February 2020

volume

70

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12 February 2020

issue

6

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12 February 2020

page(s)

591-600

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Laminin-332 is a substrate for hepsin, a protease associated with prostate cancer progression

12 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2925264

Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis

5 July 2018

1 reference

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Dissociation of epithelial and neuroendocrine carcinoma lineages in the transgenic adenocarcinoma of mouse prostate model of prostate cancer

5 July 2018

1 reference

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The roles of proteolytic enzymes in the development of tumour-induced bone disease in breast and prostate cancer

5 July 2018

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Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence

5 July 2018

1 reference

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Hepsin and prostate cancer

5 July 2018

1 reference

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Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture

5 July 2018

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Gene expression profiles in prostate cancer: association with patient subgroups and tumour differentiation.

5 July 2018

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Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee.

5 July 2018

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Unusual subtypes of prostate cancer

5 July 2018

1 reference

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Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

5 July 2018

1 reference

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Hepsin and maspin are inversely expressed in laser capture microdissectioned prostate cancer

5 July 2018

1 reference

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Molecular characterization of a metastatic neuroendocrine cell cancer arising in the prostates of transgenic mice

5 July 2018

1 reference

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Decrease and gain of gene expression are equally discriminatory markers for prostate carcinoma: a gene expression analysis on total and microdissected prostate tissue

5 July 2018

1 reference

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Delineation of prognostic biomarkers in prostate cancer

5 July 2018

1 reference

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A probasin-large T antigen transgenic mouse line develops prostate adenocarcinoma and neuroendocrine carcinoma with metastatic potential.

5 July 2018

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Small cell carcinoma of the urinary bladder. Presentation of 23 cases and review of 134 published cases

5 July 2018

1 reference

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A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2925264

MYC oncogenes and human neoplastic disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2925264

Prostate cancer progression, metastasis, and gene expression in transgenic mice

5 July 2018

1 reference

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Proteolytic remodeling of extracellular matrix

5 July 2018

1 reference

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Prostate cancer in a transgenic mouse

5 July 2018

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Revised classification of neuroendocrine tumours of the lung, pancreas and gut

5 July 2018

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Prostatic adenocarcinoma with carcinoidal features producing adrenocorticotropic syndrome. Immunohistochemical study and review of the literature

5 July 2018

1 reference

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Hepsin promotes prostate cancer progression and metastasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2925264

Hepsin is highly over expressed in and a new candidate for a prognostic indicator in prostate cancer

28 October 2018

1 reference

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Myc-driven murine prostate cancer shares molecular features with human prostate tumors

28 October 2018

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Molecular genetic profiling of Gleason grade 4/5 prostate cancers compared to benign prostatic hyperplasia

28 October 2018

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Expression profiling reveals hepsin overexpression in prostate cancer.

28 October 2018

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Human prostate cancer and benign prostatic hyperplasia: molecular dissection by gene expression profiling

28 October 2018

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Gene expression correlates of clinical prostate cancer behavior

28 October 2018

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12 December 2020

The endocrine component of prostatic carcinomas, mixed adenocarcinoma-carcinoid tumours and non-tumour prostate. Histochemical and ultrastructural identification of the endocrine cells

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12 December 2020

Primary prostatic carcinoid tumor with intracytoplasmic prostatic acid phosphatase and prostate-specific antigen

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12 December 2020

Somatostatin and/or somatostatin-like immunoreactive endocrine-paracrine cells in the human prostate gland

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12 December 2020

Expression of the c-myc protooncogene in human prostatic carcinoma and benign prostatic hyperplasia

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12 December 2020

Prostatic carcinoma: histological and immunohistological factors affecting prognosis

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12 December 2020

Detection of c-myc oncogene amplification and chromosomal anomalies in metastatic prostatic carcinoma by fluorescence in situ hybridization

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12 December 2020

Use of multiple biomarkers for a molecular diagnosis of prostate cancer

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12 December 2020

Detection of chromosomal anomalies and c-myc gene amplification in the cribriform pattern of prostatic intraepithelial neoplasia and carcinoma by fluorescence in situ hybridization

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12 December 2020

Emerging roles for proteinases in cancer

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12 December 2020

Clinical significance of alterations of chromosome 8 in high-grade, advanced, nonmetastatic prostate carcinoma

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12 December 2020

Identifiers

DOI

10.1002/PROS.21093

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19938013%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

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12 February 2020

PubMed publication ID

19938013

1 reference