The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells. (Q34078444)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20082326%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells (English)

1 reference

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16 January 2020

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6

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16 January 2020

8

Andre J van Wijnen

1 reference

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16 January 2020

10

Gary S Stein

1 reference

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16 January 2020

7

Jane B Lian

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16 January 2020

9

Janet L Stein

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16 January 2020

Margaretha van der Deen

series ordinal

1

object named as

Margaretha van der Deen

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16 January 2020

2

Jacqueline Akech

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16 January 2020

5

Dario C Altieri

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16 January 2020

author name string

Tao Wang

series ordinal

3

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16 January 2020

Thomas J FitzGerald

series ordinal

4

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16 January 2020

language of work or name

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1 March 2010

1 reference

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Journal of Cellular Biochemistry

16 January 2020

published in

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16 January 2020

volume

109

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16 January 2020

page(s)

828-837

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16 January 2020

issue

4

1 reference

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Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions

16 January 2020

cites work

1 reference

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Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).

5 July 2018

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Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells

5 July 2018

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Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA

5 July 2018

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CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P

5 July 2018

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Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma.

5 July 2018

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Androgenic control of transforming growth factor-beta signaling in prostate epithelial cells through transcriptional suppression of transforming growth factor-beta receptor II.

5 July 2018

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Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells

5 July 2018

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5 July 2018

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Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

5 July 2018

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Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential.

5 July 2018

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Runx2 disruption promotes immortalization and confers resistance to oncogene-induced senescence in primary murine fibroblasts

5 July 2018

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Molecular pathogenesis of osteosarcoma.

5 July 2018

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Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone.

5 July 2018

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Cyclin D1-cdk4 induce runx2 ubiquitination and degradation

5 July 2018

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RUNX1 (AML-1) and RUNX2 (AML-3) cooperate with prostate-derived Ets factor to activate transcription from the PSA upstream regulatory region.

5 July 2018

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The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion

5 July 2018

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Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.

5 July 2018

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Functional epigenomics identifies genes frequently silenced in prostate cancer

5 July 2018

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The RUNX genes: gain or loss of function in cancer

5 July 2018

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Functions and regulation of transforming growth factor-beta (TGF-beta) in the prostate

5 July 2018

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Human osteocalcin and bone sialoprotein mediating osteomimicry of prostate cancer cells: role of cAMP-dependent protein kinase A signaling pathway

5 July 2018

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The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts

5 July 2018

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Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription.

5 July 2018

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Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease.

5 July 2018

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The Runx2 transcription factor plays a key role in the 1alpha,25-dihydroxy Vitamin D3-dependent upregulation of the rat osteocalcin (OC) gene expression in osteoblastic cells

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

5 July 2018

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5 July 2018

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Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts

28 October 2018

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28 October 2018

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12 December 2020

Differences in the cytokine profiles associated with prostate cancer cell induced osteoblastic and osteolytic lesions in bone

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12 December 2020

Prostate cancer expression of runt‐domain transcription factor Runx2, a key regulator of osteoblast differentiation and function

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12 December 2020

Reduced levels of transforming growth factor beta receptor type II in human prostate cancer: an immunohistochemical study

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12 December 2020

Runx2 and MYC collaborate in lymphoma development by suppressing apoptotic and growth arrest pathways in vivo

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12 December 2020

Identifiers

DOI

10.1002/JCB.22463

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20082326%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20082326%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference