Overexpression of junctophilin-2 does not enhance baseline function but attenuates heart failure development after cardiac stress. (Q34082800)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25092313%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Overexpression of junctophilin-2 does not enhance baseline function but attenuates heart failure development after cardiac stress (English)

1 reference

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12 March 2020

0 references

1 reference

1

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12 March 2020

Long-Sheng Song

9

1 reference

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5

Caimei Zhang

1 reference

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12 March 2020

4

Biyi Chen

1 reference

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12 March 2020

6

William J Kutschke

1 reference

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12 March 2020

author name string

Xiaoying Zhang

2

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12 March 2020

Venkat Ramesh Iyer

3

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12 March 2020

Robert M Weiss

7

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12 March 2020

Clara Franzini-Armstrong

8

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language of work or name

English

0 references

publication date

4 August 2014

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

12 March 2020

published in

1 reference

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12 March 2020

volume

111

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12 March 2020

issue

33

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12 March 2020

page(s)

12240-12245

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Calpain-dependent cleavage of junctophilin-2 and T-tubule remodeling in a mouse model of reversible heart failure

12 March 2020

cites work

1 reference

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Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure.

5 July 2018

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In vivo suppression of microRNA-24 prevents the transition toward decompensated hypertrophy in aortic-constricted mice

5 July 2018

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Induced overexpression of Na(+)/Ca(2+) exchanger does not aggravate myocardial dysfunction induced by transverse aortic constriction

5 July 2018

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Mir-24 regulates junctophilin-2 expression in cardiomyocytes

5 July 2018

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In situ confocal imaging in intact heart reveals stress-induced Ca(2+) release variability in a murine catecholaminergic polymorphic ventricular tachycardia model of type 2 ryanodine receptor(R4496C+/-) mutation

5 July 2018

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Ultrastructural remodelling of Ca(2+) signalling apparatus in failing heart cells

5 July 2018

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Calsequestrin accumulation in rough endoplasmic reticulum promotes perinuclear Ca2+ release

5 July 2018

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β-Adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction.

5 July 2018

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Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension.

5 July 2018

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Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in mice

5 July 2018

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T-tubule remodeling during transition from hypertrophy to heart failure.

5 July 2018

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Optical single-channel resolution imaging of the ryanodine receptor distribution in rat cardiac myocytes

5 July 2018

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Induced overexpression of Na+/Ca2+ exchanger transgene: altered myocyte contractility, [Ca2+]i transients, SR Ca2+ contents, and action potential duration

5 July 2018

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Three-dimensional electron microscopy reveals new details of membrane systems for Ca2+ signaling in the heart

5 July 2018

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Mutations in JPH2-encoded junctophilin-2 associated with hypertrophic cardiomyopathy in humans

5 July 2018

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Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia

5 July 2018

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5 July 2018

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Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies

5 July 2018

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Increased exchange current but normal Ca2+ transport via Na+-Ca2+ exchange during cardiac hypertrophy after myocardial infarction.

5 July 2018

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Altered Na/Ca exchange activity in cardiac hypertrophy and heart failure: a new target for therapy?

5 July 2018

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5 July 2018

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Junctophilins: a novel family of junctional membrane complex proteins

5 July 2018

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Local control models of cardiac excitation-contraction coupling. A possible role for allosteric interactions between ryanodine receptors

5 July 2018

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Effects of overexpression of the Na+-Ca2+ exchanger on [Ca2+]i transients in murine ventricular myocytes

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Ca2+-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle

5 July 2018

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Role of Na/Ca exchange and the plasma membrane Ca2+-ATPase in cell function. Conference on Na/Ca exchange

28 October 2018

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Excitation-contraction coupling in Na+-Ca2+ exchanger knockout mice: reduced transsarcolemmal Ca2+ flux.

28 October 2018

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Reengineering inducible cardiac-specific transgenesis with an attenuated myosin heavy chain promoter

28 October 2018

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Ca2+ sparks in rabbit ventricular myocytes evoked by action potentials: involvement of clusters of L-type Ca2+ channels

28 October 2018

1 reference

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Cellular basis of abnormal calcium transients of failing human ventricular myocytes

28 October 2018

1 reference

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Ca2+ signalling between single L-type Ca2+ channels and ryanodine receptors in heart cells

28 October 2018

1 reference

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Direct measurement of SR release flux by tracking 'Ca2+ spikes' in rat cardiac myocytes.

28 October 2018

1 reference

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Development of the excitation-contraction coupling apparatus in skeletal muscle: association of sarcoplasmic reticulum and transverse tubules with myofibrils

28 October 2018

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12 December 2020

Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure

1 reference

12 December 2020

Na+-Ca2+ exchange and sarcoplasmic reticular Ca2+ regulation in ventricular myocytes from transgenic mice overexpressing the Na+-Ca2+ exchanger

1 reference

12 December 2020

T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1412729111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25092313%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

0 references

1 reference

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12 March 2020

PubMed publication ID

25092313

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25092313%20AND%20SRC:MED&resulttype=core&format=json