Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics (Q34086509)

30 July 2017

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title

Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics (English)

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30 July 2017

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N Usman

1

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30 July 2017

L M Blatt

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 November 2000

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Journal of Clinical Investigation

30 July 2017

published in

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30 July 2017

volume

106

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30 July 2017

issue

10

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30 July 2017

page(s)

1197-1202

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Bioactivity of anti-angiogenic ribozymes targeting Flt-1 and KDR mRNA.

30 July 2017

cites work

1 reference

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5 July 2018

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Antisense oligonucleotide inhibitors for the treatment of cancer: 2. Toxicological properties of phosphorothioate oligodeoxynucleotides

5 July 2018

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Poliovirus chimeras replicating under the translational control of genetic elements of hepatitis C virus reveal unusual properties of the internal ribosomal entry site of hepatitis C virus

5 July 2018

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Vascular endothelial growth factor, a potent and selective angiogenic agent

5 July 2018

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Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism

5 July 2018

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Synthesis, deprotection, analysis and purification of RNA and ribozymes

5 July 2018

1 reference

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The regulation of blood vessel growth by vascular endothelial growth factor

5 July 2018

1 reference

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The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

5 July 2018

1 reference

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In vitro splicing of the ribosomal RNA precursor of Tetrahymena: involvement of a guanosine nucleotide in the excision of the intervening sequence

5 July 2018

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Tumor angiogenesis: therapeutic implications

5 July 2018

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Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

5 July 2018

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Sequence analysis of the 5' noncoding region of hepatitis C virus

5 July 2018

1 reference

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Acute toxicology and pharmacokinetic assessment of a ribozyme (ANGIOZYME) targeting vascular endothelial growth factor receptor mRNA in the cynomolgus monkey.

5 July 2018

1 reference

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Inhibition of hepatitis C virus (HCV)-RNA-dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes

28 October 2018

1 reference

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28 October 2018

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12 December 2020

Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance

1 reference

12 December 2020

Pharmacokinetics of an antiangiogenic ribozyme (ANGIOZYME) in the mouse

1 reference

12 December 2020

Antitumor and antimetastatic activity of ribozymes targeting the messenger RNA of vascular endothelial growth factor receptors

1 reference

12 December 2020

Pharmacokinetics and tolerability of an antiangiogenic ribozyme (ANGIOZYME) in healthy volunteers

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI11631

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30 July 2017

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30 July 2017

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