Resveratrol inhibits renal fibrosis in the obstructed kidney: potential role in deacetylation of Smad3 (Q34086829)

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8 February 2020

title

Resveratrol inhibits renal fibrosis in the obstructed kidney: potential role in deacetylation of Smad3 (English)

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8 February 2020

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1

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8 February 2020

Sharon D. Ricardo

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8 February 2020

John F. Bertram

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8 February 2020

David J Nikolic-Paterson

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8 February 2020

author name string

Xinli Qu

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8 February 2020

language of work or name

English

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publication date

22 July 2010

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The American Journal of Pathology

8 February 2020

published in

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8 February 2020

volume

177

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8 February 2020

issue

3

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8 February 2020

page(s)

1065-1071

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Lysine acetylation: codified crosstalk with other posttranslational modifications

8 February 2020

cites work

1 reference

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Resveratrol inhibits EMMPRIN expression via P38 and ERK1/2 pathways in PMA-induced THP-1 cells

5 July 2018

1 reference

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Resveratrol inhibits PDGF receptor mitogenic signaling in mesangial cells: role of PTP1B.

5 July 2018

1 reference

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The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928940

SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928940

The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928940

Inhibition of p38 mitogen-activated protein kinase and transforming growth factor-beta1/Smad signaling pathways modulates the development of fibrosis in adriamycin-induced nephropathy.

5 July 2018

1 reference

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Therapeutic potential of resveratrol: the in vivo evidence

5 July 2018

1 reference

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Transforming growth factor-beta and Smad signalling in kidney diseases.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928940

Smad3 as a mediator of the fibrotic response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928940

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

5 July 2018

1 reference

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Resveratrol antagonizes EGFR-dependent Erk1/2 activation in human androgen-independent prostate cancer cells with associated isozyme-selective PKC alpha inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928940

Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928940

Histone acetyltransferases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928940

Resveratrol, a polyphenol found in wine, reduces ischemia reperfusion injury in rat kidneys

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928940

Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells.

5 July 2018

1 reference

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Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928940

Mice lacking Smad3 are protected against streptozotocin-induced diabetic glomerulopathy

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928940

Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: implications for diabetic renal and vascular disease

28 October 2018

1 reference

12 December 2020

Resveratrol, melatonin, vitamin E, and PBN protect against renal oxidative DNA damage induced by the kidney carcinogen KBrO3

1 reference

12 December 2020

Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor ?

1 reference

12 December 2020

Smad3 is acetylated by p300/CBP to regulate its transactivation activity

1 reference

12 December 2020

Cell biology. Hypoxic hookup

1 reference

12 December 2020

10.2353/AJPATH.2010.090923

Identifiers

DOI

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8 February 2020

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8 February 2020

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