A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells. (Q34089314)

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English	A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells.	scientific article

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10 November 2019

A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells (English)

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10 November 2019

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10 November 2019

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Chernova OB

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Hunyadi A

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10 November 2019

Malaj E

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Pan H

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Crooks C

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Roe B

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5378-5392

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10 November 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204694

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Acquisition of the glioblastoma phenotype during astrocytoma progression is associated with loss of heterozygosity on 10q25-qter

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Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10.

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Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliomas.

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10.1038/SJ.ONC.1204694

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10 November 2019

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10 November 2019

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