Reconstruction of the complete human cytomegalovirus genome in a BAC reveals RL13 to be a potent inhibitor of replication. (Q34090187)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679731%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Reconstruction of the complete human cytomegalovirus genome in a BAC reveals RL13 to be a potent inhibitor of replication (English)

1 reference

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9 February 2020

0 references

2

1 reference

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9 February 2020

Brian P McSharry

7

1 reference

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9 February 2020

James Davies

9

1 reference

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9 February 2020

12

Gavin W G Wilkinson

1 reference

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9 February 2020

11

Andrew J Davison

1 reference

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9 February 2020

author name string

Richard J Stanton

1

1 reference

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9 February 2020

Derrick J Dargan

3

1 reference

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9 February 2020

Charles Cunningham

4

1 reference

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9 February 2020

Orla Sheehy

5

1 reference

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9 February 2020

Sepehr Seirafian

6

1 reference

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9 February 2020

M Lynne Neale

8

1 reference

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9 February 2020

Peter Tomasec

10

1 reference

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9 February 2020

language of work or name

English

0 references

publication date

2 August 2010

1 reference

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Journal of Clinical Investigation

9 February 2020

published in

1 reference

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9 February 2020

volume

120

1 reference

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9 February 2020

issue

9

1 reference

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9 February 2020

page(s)

3191-3208

1 reference

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Sequential mutations associated with adaptation of human cytomegalovirus to growth in cell culture

9 February 2020

cites work

1 reference

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Sequences of complete human cytomegalovirus genomes from infected cell cultures and clinical specimens

5 July 2018

1 reference

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High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169.

5 July 2018

1 reference

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Characterization of a novel Golgi apparatus-localized latency determinant encoded by human cytomegalovirus.

5 July 2018

1 reference

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Re-engineering adenovirus vector systems to enable high-throughput analyses of gene function

5 July 2018

1 reference

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Efficient replication of rhesus cytomegalovirus variants in multiple rhesus and human cell types

5 July 2018

1 reference

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HCMV gH/gL/UL128-131 interferes with virus entry into epithelial cells: evidence for cell type-specific receptors

5 July 2018

1 reference

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Genotypic analysis of two hypervariable human cytomegalovirus genes

5 July 2018

1 reference

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Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma

5 July 2018

1 reference

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Characterization of the human cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and endothelial cells.

5 July 2018

1 reference

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Cytomegalovirus UL131-128 products promote gB conformational transition and gB-gH interaction during entry into endothelial cells

5 July 2018

1 reference

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Long-term infection and shedding of human cytomegalovirus in T98G glioblastoma cells

5 July 2018

1 reference

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Cytomegalovirus destruction of focal adhesions revealed in a high-throughput Western blot analysis of cellular protein expression.

5 July 2018

1 reference

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Locating proteins in the cell using TargetP, SignalP and related tools

5 July 2018

1 reference

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Human cytomegalovirus sequences expressed in latently infected individuals promote a latent infection in vitro

5 July 2018

1 reference

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New low-viscosity overlay medium for viral plaque assays

5 July 2018

1 reference

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Analysis of the human cytomegalovirus genomic region from UL146 through UL147A reveals sequence hypervariability, genotypic stability, and overlapping transcripts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Human cytomegalovirus encodes an MHC class I-like molecule (UL142) that functions to inhibit NK cell lysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Characterization of a highly glycosylated form of the human cytomegalovirus HLA class I homologue gpUL18

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Identification and characterization of human cytomegalovirus-encoded microRNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Human cytomegalovirus UL131 open reading frame is required for epithelial cell tropism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

On the mutation rate of herpes simplex virus type 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Simple and highly efficient BAC recombineering using galK selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Prediction, conservation analysis, and structural characterization of mammalian mucin-type O-glycosylation sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Human cytomegalovirus UL131-128 genes are indispensable for virus growth in endothelial cells and virus transfer to leukocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Linkage of human cytomegalovirus glycoprotein gO variant groups identified from worldwide clinical isolates with gN genotypes, implications for disease associations and evidence for N-terminal sites of positive selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Coding potential of laboratory and clinical strains of human cytomegalovirus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Two novel spliced genes in human cytomegalovirus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Cloning of the genomes of human cytomegalovirus strains Toledo, TownevarRIT3, and Towne long as BACs and site-directed mutagenesis using a PCR-based technique

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Homology between the human cytomegalovirus RL11 gene family and human adenovirus E3 genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Inter- and intragenic variations complicate the molecular epidemiology of human cytomegalovirus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Genetic engineering using homologous recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

The genes encoding the gCIII complex of human cytomegalovirus exist in highly diverse combinations in clinical isolates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Surface expression and endocytosis of the human cytomegalovirus-encoded chemokine receptor US28 is regulated by agonist-independent phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Viable human cytomegalovirus recombinant virus with an internal deletion of the IE2 86 gene affects late stages of viral replication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Construction of a self-excisable bacterial artificial chromosome containing the human cytomegalovirus genome and mutagenesis of the diploid TRL/IRL13 gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Recombineering: a powerful new tool for mouse functional genomics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

A review of genetic differences between limited and extensively passaged human cytomegalovirus strains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

In vitro selection of human cytomegalovirus variants unable to transfer virus and virus products from infected cells to polymorphonuclear leukocytes and to grow in endothelial cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Fast screening procedures for random transposon libraries of cloned herpesvirus genomes: mutational analysis of human cytomegalovirus envelope glycoprotein genes

5 July 2018

1 reference

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Efficient lytic infection of human arterial endothelial cells by human cytomegalovirus strains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

A self-recombining bacterial artificial chromosome and its application for analysis of herpesvirus pathogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Human cytomegalovirus strain-dependent changes in NK cell recognition of infected fibroblasts.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Cloning of the human cytomegalovirus (HCMV) genome as an infectious bacterial artificial chromosome in Escherichia coli: a new approach for construction of HCMV mutants.

5 July 2018

1 reference

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Cytomegalovirus encodes a potent alpha chemokine

5 July 2018

1 reference

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Cutting edge: a novel viral TNF receptor superfamily member in virulent strains of human cytomegalovirus.

5 July 2018

1 reference

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Two clinical isolates and the Toledo strain of cytomegalovirus contain endothelial cell tropic variants that are not present in the AD169, Towne, or Davis strains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Tetracycline repressor, tetR, rather than the tetR-mammalian cell transcription factor fusion derivatives, regulates inducible gene expression in mammalian cells

5 July 2018

1 reference

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Reassessing the organization of the UL42-UL43 region of the human cytomegalovirus strain AD169 genome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

The published DNA sequence of human cytomegalovirus strain AD169 lacks 929 base pairs affecting genes UL42 and UL43.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Episomal vectors rapidly and stably produce high-titer recombinant retrovirus

5 July 2018

1 reference

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ARPE-19, a human retinal pigment epithelial cell line with differentiated properties

5 July 2018

1 reference

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Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Comparative virulence and immunogenicity of the Towne strain and a nonattenuated strain of cytomegalovirus

5 July 2018

1 reference

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Selective extraction of polyoma DNA from infected mouse cell cultures

5 July 2018

1 reference

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Development of a vaccine against mental retardation caused by cytomegalovirus infection in utero.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929729

Reactivation and recombination of multiple cytomegalovirus strains from individual organ donors

5 July 2018

1 reference

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Protective effects of Towne cytomegalovirus vaccine against low-passage cytomegalovirus administered as a challenge

5 July 2018

1 reference

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Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector

5 July 2018

1 reference

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Cloning and sequencing of a highly productive, endotheliotropic virus strain derived from human cytomegalovirus TB40/E.

5 July 2018

1 reference

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Role of human cytomegalovirus UL131A in cell type-specific virus entry and release

28 October 2018

1 reference

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Sequence variability of human cytomegalovirus UL146 and UL147 genes in low-passage clinical isolates.

28 October 2018

1 reference

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Stability of human cytomegalovirus genotypes in persistently infected renal transplant recipients

28 October 2018

1 reference

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Genetic content of wild-type human cytomegalovirus.

28 October 2018

1 reference

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The human cytomegalovirus genome revisited: comparison with the chimpanzee cytomegalovirus genome.

28 October 2018

1 reference

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Human cytomegalovirus infection and expression in human malignant glioma.

28 October 2018

1 reference

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Sequence variability of the ?-chemokine UL146 from clinical strains of human cytomegalovirus

28 October 2018

1 reference

12 December 2020

Isolation and characterization of a noninfectious virion-like particle released from cells infected with human strains of cytomegalovirus

1 reference

12 December 2020

Dramatic interstrain differences in the replication of human cytomegalovirus in SCID-hu mice

1 reference

12 December 2020

Tissue macrophages are infected by human cytomegalovirus in vivo

1 reference

12 December 2020

Quantification of replication of clinical cytomegalovirus isolates in cultured endothelial cells and fibroblasts by a focus expansion assay

1 reference

12 December 2020

Fibroblasts, epithelial cells, endothelial cells and smooth muscle cells are major targets of human cytomegalovirus infection in lung and gastrointestinal tissues

1 reference

12 December 2020

Modification of human cytomegalovirus tropism through propagation in vitro is associated with changes in the viral genome

1 reference

12 December 2020

Monocyte-derived dendritic cells are permissive to the complete replicative cycle of human cytomegalovirus

1 reference

12 December 2020

Human cytomegalovirus as a direct pathogen: correlation of multiorgan involvement and cell distribution with clinical and pathological findings in a case of congenital inclusion disease

1 reference

12 December 2020

Multiple infections by cytomegalovirus in patients with acquired immunodeficiency syndrome: documentation by Southern blot hybridization

1 reference

12 December 2020

Identification of Multiple Cytomegalovirus Strains in Homosexual Men with Acquired Immunodeficiency Syndrome

1 reference

12 December 2020

Isolation of multiple strains of cytomegalovirus from women attending a clinic for sexually transmitted disease

1 reference

12 December 2020

Identification of multiple strains of cytomegalovirus in homosexual men

1 reference

12 December 2020

Preservation of natural endothelial cytopathogenicity of cytomegalovirus by propagation in endothelial cells

1 reference

12 December 2020

Coinfection of the immunocompromised but not the immunocompetent host by multiple human cytomegalovirus strains

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI42955

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679731%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679731%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference