Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer (Q34091425)

31 July 2017

Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer (English)

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31 July 2017

diffuse gastric cancer

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15

James M Ford

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31 July 2017

Lincoln D Nadauld

1

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31 July 2017

Sarah Garcia

2

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31 July 2017

Georges Natsoulis

3

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31 July 2017

John M Bell

4

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31 July 2017

Laura Miotke

5

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31 July 2017

Erik S Hopmans

6

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31 July 2017

Hua Xu

7

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31 July 2017

Reetesh K Pai

8

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31 July 2017

Curt Palm

9

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31 July 2017

John F Regan

10

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31 July 2017

Hao Chen

11

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31 July 2017

Patrick Flaherty

12

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31 July 2017

Akifumi Ootani

13

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31 July 2017

Nancy R Zhang

14

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31 July 2017

Calvin J Kuo

16

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31 July 2017

Hanlee P Ji

17

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31 July 2017

language of work or name

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27 August 2014

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31 July 2017

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31 July 2017

15

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31 July 2017

8

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31 July 2017

428

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Creative Commons Attribution 4.0 International

31 July 2017

start time

1 August 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/s13059-014-0428-9

0 references

cites work

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Genomic profile analysis of diffuse-type gastric cancers

5 July 2018

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FGFR2 amplification has prognostic significance in gastric cancer: results from a large international multicentre study

5 July 2018

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A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.

5 July 2018

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Towards the goal of personalized medicine in gastric cancer--time to move beyond HER2 inhibition. Part I: Targeting receptor tyrosine kinase gene amplification

5 July 2018

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Quantitative and Sensitive Detection of Cancer Genome Amplifications from Formalin Fixed Paraffin Embedded Tumors with Droplet Digital PCR.

5 July 2018

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FGFR2 gene amplification in gastric cancer predicts sensitivity to the selective FGFR inhibitor AZD4547.

5 July 2018

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Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis

5 July 2018

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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

5 July 2018

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Detecting and annotating genetic variations using the HugeSeq pipeline

5 July 2018

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AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family

5 July 2018

1 reference

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Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

5 July 2018

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Signet ring cell carcinoma of the stomach is significantly associated with poor prognosis and diffuse gastric cancer (Lauren's): single-center experience of 160 cases

5 July 2018

1 reference

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Personalized oncology through integrative high-throughput sequencing: a pilot study

5 July 2018

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KEGG for integration and interpretation of large-scale molecular data sets

5 July 2018

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5 July 2018

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Efficient targeted resequencing of human germline and cancer genomes by oligonucleotide-selective sequencing

5 July 2018

1 reference

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Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Mutations in CIC and FUBP1 contribute to human oligodendroglioma

5 July 2018

1 reference

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A framework for variation discovery and genotyping using next-generation DNA sequencing data

5 July 2018

1 reference

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CNVnator: an approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Estimation of parent specific DNA copy number in tumors using high-density genotyping arrays

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Expression of BMP-7 in human gastric cancer and its clinical significance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Integrative genomics viewer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Genomic and epigenetic profiles of gastric cancer: potential diagnostic and therapeutic applications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Searching NCBI's dbSNP database

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

A map of human genome variation from population-scale sequencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

5 July 2018

1 reference

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Hereditary diffuse gastric cancer: updated consensus guidelines for clinical management and directions for future research

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Targeted enrichment of specific regions in the human genome by array hybridization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Tgf-beta signaling alterations and colon cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

A method and server for predicting damaging missense mutations

5 July 2018

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The role of Crk/Dock180/Rac1 pathway in the malignant behavior of human ovarian cancer cell SKOV3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Fast and accurate long-read alignment with Burrows-Wheeler transform

5 July 2018

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Nucleotide-resolution analysis of structural variants using BreakSeq and a breakpoint library

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Combination of EGFR and MEK1/2 inhibitor shows synergistic effects by suppressing EGFR/HER3-dependent AKT activation in human gastric cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

BreakDancer: an algorithm for high-resolution mapping of genomic structural variation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

VarScan: variant detection in massively parallel sequencing of individual and pooled samples

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

TRIM36 interacts with the kinetochore protein CENP-H and delays cell cycle progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Hereditary diffuse gastric cancer: implications of genetic testing for screening and prophylactic surgery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Velvet: algorithms for de novo short read assembly using de Bruijn graphs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

g:Profiler--a web-based toolset for functional profiling of gene lists from large-scale experiments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Genetic determinants of cancer metastasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Adjuvant therapy in gastric cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Cloning and characterisation of the RBCC728/TRIM36 zinc-binding protein from the tumor suppressor gene region at chromosome 5q22.3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

dbSNP: the NCBI database of genetic variation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Inactivation of the E-cadherin gene in primary gastric carcinomas and gastric carcinoma cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

E-cadherin gene mutations in human gastric carcinoma cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

E-cadherin gene mutations provide clues to diffuse type gastric carcinomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Chromosome 5 allele loss in human colorectal carcinomas.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

A splicing mutation accounts for the lack of p53 gene expression in a CML blast crisis cell line: a novel mechanism of p53 gene inactivation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Isolation of an amplified DNA sequence in stomach cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Histogenesis of intestinal and diffuse types of gastric carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

p53 gene mutations in gastric cancer metastases and in gastric cancer cell lines derived from metastases.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

Establishment of a long-term three-dimensional primary culture of mouse glandular stomach epithelial cells within the stem cell niche

5 July 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-014-0428-9

Mutations of the human E-cadherin (CDH1) gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-014-0428-9

E-cadherin expression in sporadic gastric cancer from Mexico: exon 8 and 9 deletions are infrequent events associated with poor survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-014-0428-9

Mechanisms of inactivation of E-cadherin in breast cancer cell lines

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145231

E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma

28 October 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13059-014-0428-9

Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer

21 January 2018

1 reference

12 December 2020

A prospective study of total gastrectomy for CDH1-positive hereditary diffuse gastric cancer

1 reference

12 December 2020

Amplification of growth factor receptor genes and DNA ploidy pattern in the progression of gastric cancer

1 reference

12 December 2020

p53 mutations and microsatellite instability in sporadic gastric cancer: when guardians fail

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12 December 2020

Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model

1 reference

12 December 2020

10.1186/S13059-014-0428-9

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DOI

1 reference

Dimensions Publication ID

31 July 2017

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1 reference

31 July 2017

1 reference