Small-molecule inducers of insulin expression in pancreatic alpha-cells. (Q34093859)

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9 February 2020

title

Small-molecule inducers of insulin expression in pancreatic alpha-cells (English)

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9 February 2020

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Joshua A Bittker

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Stuart L Schreiber

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9 February 2020

author name string

Dina Fomina-Yadlin

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Deepika Walpita

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9 February 2020

Vlado Dancik

4

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9 February 2020

Jacob Hecksher-Sørensen

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Tanaz Sharifnia

7

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9 February 2020

Alykhan Shamji

8

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Paul A Clemons

9

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Bridget K Wagner

10

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language of work or name

English

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publication date

9 August 2010

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Proceedings of the National Academy of Sciences of the United States of America

9 February 2020

published in

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volume

107

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issue

34

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page(s)

15099-15104

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Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

9 February 2020

cites work

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5 July 2018

How to make beta cells?

1 reference

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The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

5 July 2018

1 reference

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Extreme makeover: converting one cell into another

5 July 2018

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Targeting RSK: an overview of small molecule inhibitors

5 July 2018

1 reference

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The RSK family of kinases: emerging roles in cellular signalling

5 July 2018

1 reference

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Promoting ectopic pancreatic fates: pancreas development and future diabetes therapies

5 July 2018

1 reference

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In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

5 July 2018

1 reference

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The RSK factors of activating the Ras/MAPK signaling cascade

5 July 2018

1 reference

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Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930573

ChemBank: a small-molecule screening and cheminformatics resource database

5 July 2018

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The selectivity of protein kinase inhibitors: a further update

5 July 2018

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Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930573

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930573

Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930573

The protein kinase complement of the human genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930573

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930573

Ex vivo expansion of human pancreatic endocrine cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930573

Comparison of cytokine effects on mouse pancreatic alpha-cell and beta-cell lines. Viability, secretory function, and MHC antigen expression

5 July 2018

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5 July 2018

Identifiers

DOI

10.1073/PNAS.1010018107

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9 February 2020

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9 February 2020

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