Allosteric block of KCa2 channels by apamin (Q34094456)

31 July 2017

Allosteric block of KCa2 channels by apamin (English)

1 reference

31 July 2017

Cédric Lamy

1

1 reference

31 July 2017

Samuel J Goodchild

2

1 reference

31 July 2017

Kate L Weatherall

3

1 reference

31 July 2017

David E Jane

4

1 reference

31 July 2017

Jean-François Liégeois

5

1 reference

31 July 2017

Vincent Seutin

6

1 reference

31 July 2017

Neil V Marrion

7

1 reference

31 July 2017

language of work or name

English

0 references

publication date

18 June 2010

1 reference

Journal of Biological Chemistry

31 July 2017

1 reference

31 July 2017

285

1 reference

31 July 2017

35

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31 July 2017

27067-27077

1 reference

Inhibition of K(Ca)2.2 and K(Ca)2.3 channel currents by protonation of outer pore histidine residues

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Activation of the SK potassium channel-calmodulin complex by nanomolar concentrations of terbium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Molecular and cellular basis of small--and intermediate-conductance, calcium-activated potassium channel function in the brain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

An amino acid outside the pore region influences apamin sensitivity in small conductance Ca2+-activated K+ channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Ca(2+)-activated K+ channels: molecular determinants and function of the SK family

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

The SK3 Subunit of Small Conductance Ca2+-activated K+ Channels Interacts with Both SK1 and SK2 Subunits in a Heterologous Expression System

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Modulation of small conductance calcium-activated potassium (SK) channels: a new challenge in medicinal chemistry

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Design and characterization of a highly selective peptide inhibitor of the small conductance calcium-activated K+ channel, SkCa2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Characterisation of [(125)I]-apamin binding sites in rat brain membranes with HE293 cells transfected with SK channel subtypes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Bis-quinolinium cyclophanes: 6,10-diaza-3(1,3),8(1,4)-dibenzena-1,5(1,4)- diquinolinacyclodecaphane (UCL 1684), the first nanomolar, non-peptidic blocker of the apamin-sensitive Ca(2+)-activated K+ channel.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Determinants of apamin and d-tubocurarine block in SK potassium channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Small-conductance, calcium-activated potassium channels from mammalian brain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Solution structure of apamin determined by nuclear magnetic resonance and distance geometry.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Effects of apamin, quinine and neuromuscular blockers on calcium-activated potassium channels in guinea-pig hepatocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Competition for block of a Ca2(+)-activated K+ channel by charybdotoxin and tetraethylammonium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Single apamin-blocked Ca-activated K+ channels of small conductance in cultured rat skeletal muscle

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

The aromatic binding site for tetraethylammonium ion on potassium channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

A Functional Connection Between the Pores of Distantly Related Ion Channels as Revealed by Mutant K + Channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Structure-function relations and site of action of apamin, a neurotoxic polypeptide of bee venom with an action on the central nervous system

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Methyl-laudanosine: a new pharmacological tool to investigate the function of small-conductance Ca(2+)-activated K(+) channels

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.110072

Inwardly rectifying current-voltage relationship of small-conductance Ca2+-activated K+ channels rendered by intracellular divalent cation blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.110072

Partial apamin sensitivity of human small conductance Ca2+-activated K+ channels stably expressed in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.110072

Identification of a pharmacophore of SKCa channel blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.110072

Synthesis and structure-activity relationship studies of 2-(N-substituted)-aminobenzimidazoles as potent negative gating modulators ofsmall conductance Ca2+-activated K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.110072

Structural basis of TEA blockade in a model potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.110072

A cation-pi interaction between extracellular TEA and an aromatic residue in potassium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.110072

External tetraethylammonium as a molecular caliper for sensing the shape of the outer vestibule of potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.110072

Characterization of the outer pore region of the apamin-sensitive Ca2+-activated K+ channel rSK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.110072

Synthesis and biological evaluation of N-methyl-laudanosine iodide analogues as potential SK channel blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.110072

Apamin interacts with all subtypes of cloned small-conductance Ca2+-activated K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.110072

Preparation of a pure monoiodo derivative of the bee venom neurotoxin apamin and its binding properties to rat brain synaptosomes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930706

Binding and toxicity of apamin. Characterization of the active site

28 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.110072

Dequalinium: a potent inhibitor of apamin-sensitive K+ channels in hepatocytes and of nicotinic responses in skeletal muscle

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20562108

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pore mutations in Shaker K+ channels distinguish between the sites of tetraethylammonium blockade and C-type inactivation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20562108

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.110072

1 reference

31 July 2017

1 reference

31 July 2017

1 reference