Molecular imaging of the efficacy of heat shock protein 90 inhibitors in living subjects (Q34096497)

31 July 2017

title

Molecular imaging of the efficacy of heat shock protein 90 inhibitors in living subjects (English)

1 reference

31 July 2017

5

Gabriela Chiosis

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author name string

Carmel T Chan

1

1 reference

31 July 2017

Ramasamy Paulmurugan

2

1 reference

31 July 2017

Olivier S Gheysens

3

1 reference

31 July 2017

Joungnam Kim

4

1 reference

31 July 2017

Sanjiv Sam Gambhir

6

1 reference

31 July 2017

language of work or name

English

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publication date

1 January 2008

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31 July 2017

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31 July 2017

volume

68

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31 July 2017

issue

1

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31 July 2017

page(s)

216-226

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STAT3 and MAPK signaling maintain overexpression of heat shock proteins 90alpha and beta in multiple myeloma cells, which critically contribute to tumor-cell survival

31 July 2017

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Firefly luciferase produces hydrogen peroxide as a coproduct in dehydroluciferyl adenylate formation

5 July 2018

1 reference

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Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90.

5 July 2018

1 reference

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5 July 2018

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5 July 2018

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Evaluation of 8-arylsulfanyl, 8-arylsulfoxyl, and 8-arylsulfonyl adenine derivatives as inhibitors of the heat shock protein 90.

5 July 2018

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5 July 2018

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A time-resolved fluorescence resonance energy transfer-based HTS assay and a surface plasmon resonance-based binding assay for heat shock protein 90 inhibitors

5 July 2018

1 reference

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Synthesis and biological evaluation of a new class of geldanamycin derivatives as potent inhibitors of Hsp90.

5 July 2018

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Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90.

5 July 2018

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5 July 2018

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Targeting multiple signal transduction pathways through inhibition of Hsp90.

5 July 2018

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Imaging the pharmacodynamics of HER2 degradation in response to Hsp90 inhibitors

5 July 2018

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Molecular imaging of homodimeric protein-protein interactions in living subjects

5 July 2018

1 reference

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Optimizing luciferase protein fragment complementation for bioluminescent imaging of protein-protein interactions in live cells and animals

5 July 2018

1 reference

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Hsp90 isoforms: functions, expression and clinical importance

5 July 2018

1 reference

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Molecular imaging of drug-modulated protein-protein interactions in living subjects

5 July 2018

1 reference

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Inhibition of GR-mediated transcription by p23 requires interaction with Hsp90.

5 July 2018

1 reference

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Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine

5 July 2018

1 reference

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5 July 2018

Heat shock protein 90.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Development of Purine-Scaffold Small Molecule Inhibitors of Hsp90

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Development of Radicicol Analogues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Comparative analysis of the ATP-binding sites of Hsp90 by nucleotide affinity cleavage: a distinct nucleotide specificity of the C-terminal ATP-binding site

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Monitoring Protein−Protein Interactions Using Split Synthetic Renilla Luciferase Protein-Fragment-Assisted Complementation

5 July 2018

1 reference

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Visualizing protein-protein interactions in living animals

5 July 2018

1 reference

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Noninvasive imaging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies

5 July 2018

1 reference

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Development of a purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells and induce the degradation of Her2 tyrosine kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Noninvasive imaging of protein-protein interactions in living animals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Optical imaging of Renilla luciferase reporter gene expression in living mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Dimerization and N-terminal domain proximity underlie the function of the molecular chaperone heat shock protein 90

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Expression of hsp90 and cyclin D1 in human breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Mechanism of Dimer Formation of the 90‐kDa Heat‐Shock Protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

New colorimetric cytotoxicity assay for anticancer-drug screening

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Synthesis of a red-shifted fluorescence polarization probe for Hsp90.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

High-throughput screening assay for inhibitors of heat-shock protein 90 ATPase activity

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4146344

Phase I trial of 17-allylamino-17-demethoxygeldanamycin in patients with advanced cancer

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18172314

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Synthesis of Hsp90 dimerization modulators

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18172314

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chaperoning cell death: a critical dual role for Hsp90 in small-cell lung cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18172314

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-07-2268

1 reference

31 July 2017

1 reference

31 July 2017

1 reference