Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy (Q34098441)

31 July 2017

Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy (English)

1 reference

31 July 2017

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David A Zeevi

1

1 reference

31 July 2017

Shaya Lev

2

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31 July 2017

Ayala Frumkin

3

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31 July 2017

Baruch Minke

4

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31 July 2017

Gideon Bach

5

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31 July 2017

language of work or name

English

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publication date

24 August 2010

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31 July 2017

Journal of Cell Science

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31 July 2017

123

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31 July 2017

Pt 18

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31 July 2017

3112-3124

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describes a project that uses

31 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2931605/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Constitutive activity of the human TRPML2 channel induces cell degeneration

28 July 2018

1 reference

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Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis

28 July 2018

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The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy

28 July 2018

1 reference

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The calcium channel mucolipin-3 is a novel regulator of trafficking along the endosomal pathway

28 July 2018

1 reference

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Life and death of sensory hair cells expressing constitutively active TRPML3

28 July 2018

1 reference

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Motor deficit in a Drosophila model of mucolipidosis type IV due to defective clearance of apoptotic cells.

28 July 2018

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The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel

28 July 2018

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Autophagic dysfunction in mucolipidosis type IV patients

28 July 2018

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The varitint-waddler mouse phenotypes and the TRPML3 ion channel mutation: cause and consequence

28 July 2018

1 reference

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Membrane traffic and turnover in TRP-ML1-deficient cells: a revised model for mucolipidosis type IV pathogenesis

28 July 2018

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A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype

28 July 2018

1 reference

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A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse

28 July 2018

1 reference

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Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice.

28 July 2018

1 reference

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Gain-of-function mutation in TRPML3 causes the mouse Varitint-Waddler phenotype

28 July 2018

1 reference

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Neurologic, gastric, and opthalmologic pathologies in a murine model of mucolipidosis type IV

28 July 2018

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28 July 2018

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Methods for monitoring autophagy from yeast to human

28 July 2018

1 reference

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Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact living cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

Mucolipin-1 is a lysosomal membrane protein required for intracellular lactosylceramide traffic

28 July 2018

1 reference

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Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes

28 July 2018

1 reference

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TRP-ML1 regulates lysosomal pH and acidic lysosomal lipid hydrolytic activity

28 July 2018

1 reference

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Autophagy: molecular machinery for self-eating

28 July 2018

1 reference

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Cation channel activity of mucolipin-1: the effect of calcium.

28 July 2018

1 reference

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Mucolipin 1: endocytosis and cation channel--a review

28 July 2018

1 reference

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Autophagy: many paths to the same end.

28 July 2018

1 reference

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CUPpling calcium to lysosomal biogenesis.

28 July 2018

1 reference

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Autophagy: in sickness and in health

28 July 2018

1 reference

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Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis

28 July 2018

1 reference

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Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

Mucolipidosis type IV: novel MCOLN1 mutations in Jewish and non-Jewish patients and the frequency of the disease in the Ashkenazi Jewish population

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel

28 July 2018

1 reference

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

28 July 2018

1 reference

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Functional multimerization of mucolipin channel proteins.

28 July 2018

1 reference

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The tissue-specific expression of TRPML2 (MCOLN-2) gene is influenced by the presence of TRPML1.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

TRPMLs: in sickness and in health

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

Chaperone-mediated autophagy is defective in mucolipidosis type IV.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

The varitint-waddler (Va) deafness mutation in TRPML3 generates constitutive, inward rectifying currents and causes cell degeneration

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

Mucolipin-2 localizes to the Arf6-associated pathway and regulates recycling of GPI-APs

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

TRPML and lysosomal function

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

Lysosomal exocytosis is impaired in mucolipidosis type IV.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

Overexpression of wild-type and mutant mucolipin proteins in mammalian cells: effects on the late endocytic compartment organization.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

Molecular pathophysiology of mucolipidosis type IV: pH dysregulation of the mucolipin-1 cation channel.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

28 October 2018

Mucolipidosis type IV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931605

A potentially dynamic lysosomal role for the endogenous TRPML proteins

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20736310

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/JCS.067330

1 reference

31 July 2017

1 reference

31 July 2017

1 reference