Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer (Q34101115)

31 July 2017

Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer (English)

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31 July 2017

T Sato

1

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31 July 2017

A Nakashima

2

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31 July 2017

L Guo

3

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31 July 2017

K Coffman

4

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31 July 2017

F Tamanoi

5

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31 July 2017

language of work or name

English

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publication date

1 March 2010

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31 July 2017

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31 July 2017

29

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31 July 2017

18

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31 July 2017

2746-2752

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https://scigraph.springernature.com/pub.10.1038/onc.2010.28

31 July 2017

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cites work

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Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

Cell cycle control by the CDC25 phosphatases

5 July 2018

1 reference

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Isolation of hyperactive mutants of mammalian target of rapamycin

5 July 2018

1 reference

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CDC25A levels determine the balance of proliferation and checkpoint response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

mTOR is activated in the majority of malignant melanomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

Targeting the mTOR signaling network in cancer.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

Dissecting the Akt/mammalian target of rapamycin signaling network: emerging results from the head and neck cancer tissue array initiative.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

Defining the role of mTOR in cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

Point mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

Stress and mTORture signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

mTOR and cancer: insights into a complex relationship

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

TOR signaling in growth and metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

The KRAS oncogene: past, present, and future

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

Dysregulation of the TSC-mTOR pathway in human disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

Cdc25 phosphatases and cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

Messenger functions of phosphatidic acid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2953941

An activated mTOR mutant supports growth factor-independent, nutrient-dependent cell survival

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2010.28

Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2010.28

Activation of the mTOR signaling pathway in renal clear cell carcinoma

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2010.28

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.28

1 reference

Dimensions Publication ID

31 July 2017

0 references

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31 July 2017

1 reference