Ion channel trafficking: a new therapeutic horizon for atrial fibrillation (Q34101658)

31 July 2017

1 reference

title

Ion channel trafficking: a new therapeutic horizon for atrial fibrillation (English)

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31 July 2017

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Sarah M Schumacher

1

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31 July 2017

Jeffrey R Martens

series ordinal

2

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31 July 2017

publication date

13 February 2010

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31 July 2017

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31 July 2017

volume

7

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31 July 2017

issue

9

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31 July 2017

page(s)

1309-1315

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Other drugs acting on nervous system associated with QT-interval prolongation

31 July 2017

cites work

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Cholesterol modulates the recruitment of Kv1.5 channels from Rab11-associated recycling endosome in native atrial myocytes

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Nonpharmacologic strategies: the evolving story of ablation and hybrid therapy

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Rhythm control versus rate control for atrial fibrillation and heart failure

5 July 2018

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Potassium channels in atrial fibrillation: targets for atrial and pathology-specific therapy?

5 July 2018

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The anchoring protein SAP97 retains Kv1.5 channels in the plasma membrane of cardiac myocytes

5 July 2018

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Safety considerations in the pharmacological management of atrial fibrillation

5 July 2018

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Electrical and pharmacologic cardioversion for atrial fibrillation

5 July 2018

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Drugs and trafficking of ion channels: a new pro-arrhythmic threat on the horizon?

5 July 2018

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Coexistence of hERG current block and disruption of protein trafficking in ketoconazole-induced long QT syndrome

5 July 2018

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Localization and trafficking of cardiac voltage-gated potassium channels

5 July 2018

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hERG channel trafficking: novel targets in drug-induced long QT syndrome

5 July 2018

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Co-chaperone FKBP38 promotes HERG trafficking

5 July 2018

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HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Personnel, Policy, Procedures and Follow-Up

5 July 2018

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Membrane cholesterol modulates Kv1.5 potassium channel distribution and function in rat cardiomyocytes

5 July 2018

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Mechanisms of cardiac potassium channel trafficking

5 July 2018

1 reference

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Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes

5 July 2018

1 reference

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S-acylation regulates Kv1.5 channel surface expression

5 July 2018

1 reference

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SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5.

5 July 2018

1 reference

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Innovative approaches to anti-arrhythmic drug therapy.

5 July 2018

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Functional studies of individual myosin molecules

5 July 2018

1 reference

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Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine.

5 July 2018

1 reference

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Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation

5 July 2018

1 reference

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A perspective on antiarrhythmic drug therapy to treat atrial fibrillation: there remains an unmet need

5 July 2018

1 reference

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A specific N-terminal residue in Kv1.5 is required for upregulation of the channel by SAP97.

5 July 2018

1 reference

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Evidence for proteasomal degradation of Kv1.5 channel protein

5 July 2018

1 reference

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Kv1.5 surface expression is modulated by retrograde trafficking of newly endocytosed channels by the dynein motor

5 July 2018

1 reference

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HERG channel trafficking.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Advances in antiarrhythmic drug treatment of atrial fibrillation: where do we stand now?

5 July 2018

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Worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation

5 July 2018

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Pentamidine reduces hERG expression to prolong the QT interval

5 July 2018

1 reference

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Coupled tertiary folding and oligomerization of the T1 domain of Kv channels

5 July 2018

1 reference

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Blockers of the Kv1.5 channel for the treatment of atrial arrhythmias

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Caveolin-3 and SAP97 form a scaffolding protein complex that regulates the voltage-gated potassium channel Kv1.5

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Rab GTPases and myosin motors in organelle motility

5 July 2018

1 reference

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5 July 2018

1 reference

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Progress in nonpharmacologic therapy of atrial fibrillation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

5 July 2018

The Birth of a Channel

1 reference

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SAP97 increases Kv1.5 currents through an indirect N-terminal mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG.

5 July 2018

1 reference

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Quality control in the endoplasmic reticulum

5 July 2018

1 reference

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Endocytosis and sorting of glycosphingolipids in sphingolipid storage disease

5 July 2018

1 reference

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Myosin-V, a versatile motor for short-range vesicle transport

5 July 2018

1 reference

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Modulation of the human Kv1.5 channel by protein kinase C activation: role of the Kvbeta1.2 subunit

5 July 2018

1 reference

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Increased atrial fibrillation mortality: United States, 1980-1998.

5 July 2018

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Potassium channel ontogeny

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Modulation of Kv1.5 currents by protein kinase A, tyrosine kinase, and protein tyrosine phosphatase requires an intact cytoskeleton

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Hypoxic pulmonary vasoconstriction: role of voltage-gated potassium channels

5 July 2018

1 reference

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The pathobiology of pulmonary hypertension. Smooth muscle cells and ion channels

5 July 2018

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Validation of Clinical Classification Schemes for Predicting Stroke

5 July 2018

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Targeted replacement of KV1.5 in the mouse leads to loss of the 4-aminopyridine-sensitive component of I(K,slow) and resistance to drug-induced qt prolongation.

5 July 2018

1 reference

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Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study

5 July 2018

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alpha-actinin-2 couples to cardiac Kv1.5 channels, regulating current density and channel localization in HEK cells

5 July 2018

1 reference

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Cooperation between microtubule- and actin-based motor proteins

5 July 2018

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Phosphorylation is required for alteration of kv1.5 K(+) channel function by the Kvbeta1.3 subunit

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Protein kinase A phosphorylation alters Kvbeta1.3 subunit-mediated inactivation of the Kv1.5 potassium channel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Inhibition of cardiac potassium currents by the vesnarinone analog OPC-18790: comparison with quinidine and dofetilide

5 July 2018

1 reference

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Functional differences in Kv1.5 currents expressed in mammalian cell lines are due to the presence of endogenous Kv beta 2.1 subunits

5 July 2018

1 reference

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Localization of the Kv1.5 K+ channel protein in explanted cardiac tissue

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

A novel K+ channel beta-subunit (hKv beta 1.3) is produced via alternative mRNA splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Mechanisms of action of lidocaine and quinidine on action potential duration in rabbit cardiac Purkinje fibers. An effect on steady state sodium currents?

5 July 2018

1 reference

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Characteristics and prognosis of lone atrial fibrillation. 30-year follow-up in the Framingham Study

5 July 2018

1 reference

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Atrial fibrillation as an independent risk factor for stroke: the Framingham Study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Modulation of the voltage-gated potassium channel Kv1.5 by the SGK1 protein kinase involves inhibition of channel ubiquitination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Inhibition of hERG channel trafficking: an under-explored mechanism for drug-induced QT prolongation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Posttranslational modification of voltage-dependent potassium channel Kv1.5: COOH-terminal palmitoylation modulates its biological properties

28 October 2018

1 reference

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ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation--excutive summary

28 October 2018

1 reference

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Rab-GTPase-dependent endocytic recycling of Kv1.5 in atrial myocytes.

28 October 2018

1 reference

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Binding site of a novel Kv1.5 blocker: a "foot in the door" against atrial fibrillation.

28 October 2018

1 reference

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Human cardiac potassium channel DNA polymorphism modulates access to drug-binding site and causes drug resistance

28 October 2018

1 reference

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Pentamidine-induced long QT syndrome and block of hERG trafficking

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Molecular basis for Kv1.5 channel block: conservation of drug binding sites among voltage-gated K+ channels

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Rabs, Rips, FIPs, and endocytic membrane traffic.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Assembly with the Kvbeta1.3 subunit modulates drug block of hKv1.5 channels

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Isoform-specific localization of voltage-gated K+ channels to distinct lipid raft populations. Targeting of Kv1.5 to caveolae

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Distinct domains of the voltage-gated K+ channel Kv beta 1.3 beta-subunit affect voltage-dependent gating.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Assembly of mammalian voltage-gated potassium channels: evidence for an important role of the first transmembrane segment.

28 October 2018

1 reference

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Recurrence of pulmonary vein conduction and atrial fibrillation after pulmonary vein isolation for atrial fibrillation: A randomized trial of the ostial versus the extraostial ablation strategy

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932854

Prevalence of asymptomatic recurrences of atrial fibrillation after successful radiofrequency catheter ablation

28 October 2018

1 reference

12 December 2020

Sustained depolarization-induced outward current in human atrial myocytes. Evidence for a novel delayed rectifier K+ current similar to Kv1.5 cloned channel currents

1 reference

12 December 2020

K+ channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes

1 reference

12 December 2020

Differences between outward currents of human atrial and subepicardial ventricular myocytes

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12 December 2020

PATIENTS WITH MITRAL STENOSIS AND SYSTEMIC EMBOLI; HEMODYNAMIC AND CLINICAL OBSERVATIONS

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12 December 2020

Freedom from atrial tachyarrhythmias after catheter ablation of atrial fibrillation: a randomized comparison between 2 current ablation strategies

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12 December 2020

Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications

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12 December 2020

Alterations in potassium channel gene expression in atria of patients with persistent and paroxysmal atrial fibrillation: differential regulation of protein and mRNA levels for K+channels

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12 December 2020

Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation

1 reference

12 December 2020

10.1016/J.HRTHM.2010.02.017

Identifiers

DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference