The Sir2 protein family: A novel deacetylase for gene silencing and more (Q34103214)

31 July 2017

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title

The Sir2 protein family: A novel deacetylase for gene silencing and more (English)

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31 July 2017

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Shore D

1

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PubMed ID

11114164

31 July 2017

language of work or name

English

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publication date

1 December 2000

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Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

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31 July 2017

97

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31 July 2017

26

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31 July 2017

14030-14032

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Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

Locus specificity determinants in the multifunctional yeast silencing protein Sir2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

Sir2 links chromatin silencing, metabolism, and aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

Heterochromatin function in complex genomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

5 July 2018

https://api.crossref.org/works/10.1073%2FPNAS.011506198

Cellular memory of transcriptional states by Polycomb-group proteins.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34090

Yeast heterochromatin: regulation of its assembly and inheritance by histones

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.011506198

Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.011506198

CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis i

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.011506198

21 January 2018

Identifiers

DOI

10.1073/PNAS.011506198

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference

PubMed ID

11114164