Lentiviral overexpression of GRK6 alleviates L-dopa-induced dyskinesia in experimental Parkinson's disease (Q34105586)

31 July 2017

title

Lentiviral overexpression of GRK6 alleviates L-dopa-induced dyskinesia in experimental Parkinson's disease (English)

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31 July 2017

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Vsevolod V Gurevich

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31 July 2017

14

Eugenia V Gurevich

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31 July 2017

Mohamed R Ahmed

1

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31 July 2017

Amandine Berthet

2

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31 July 2017

Evgeny Bychkov

3

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31 July 2017

Gregory Porras

4

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31 July 2017

Qin Li

5

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31 July 2017

Bernard H Bioulac

6

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31 July 2017

Yonatan T Carl

7

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31 July 2017

Bertrand Bloch

8

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31 July 2017

Seunghyi Kook

9

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31 July 2017

Incarnation Aubert

10

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31 July 2017

Sandra Dovero

11

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31 July 2017

Evelyne Doudnikoff

12

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31 July 2017

Erwan Bezard

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31 July 2017

language of work or name

English

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publication date

1 April 2010

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Science Translational Medicine

31 July 2017

published in

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31 July 2017

volume

2

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31 July 2017

issue

28

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31 July 2017

page(s)

28ra28

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How do you treat motor complications in Parkinson's disease: Medicine, surgery, or both?

31 July 2017

cites work

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Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment

5 July 2018

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Beta-arrestins and cell signaling

5 July 2018

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Arrestins and two receptor kinases are upregulated in Parkinson's disease with dementia

5 July 2018

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Regulation of receptor trafficking by GRKs and arrestins

5 July 2018

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Arrestins: ubiquitous regulators of cellular signaling pathways

5 July 2018

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Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors.

5 July 2018

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D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways.

5 July 2018

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Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice

5 July 2018

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Cellular regulation of RGS proteins: modulators and integrators of G protein signaling

5 July 2018

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Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease.

5 July 2018

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Pathophysiology of levodopa-induced dyskinesia: potential for new therapies

5 July 2018

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Pallidal border cells: an anatomical and electrophysiological study in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey

5 July 2018

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Dopamine agonist-induced dyskinesias are correlated to both firing pattern and frequency alterations of pallidal neurones in the MPTP-treated monkey

5 July 2018

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Enhanced morphine analgesia in mice lacking beta-arrestin 2

5 July 2018

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Differential regulation of striatal preproenkephalin and preprotachykinin mRNA levels in MPTP-lesioned monkeys chronically treated with dopamine D1 or D2 receptor agonists

5 July 2018

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L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA.

5 July 2018

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DARPP-32: regulator of the efficacy of dopaminergic neurotransmission

5 July 2018

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Induction of dopamine D3 receptor expression as a mechanism of behavioral sensitization to levodopa

5 July 2018

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Differential regulation of dopamine D1A receptor responsiveness by various G protein-coupled receptor kinases

5 July 2018

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The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain

5 July 2018

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L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain

5 July 2018

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Dopamine depletion and subsequent treatment with L-DOPA, but not the long-lived dopamine agonist pergolide, enhances activity of the Akt pathway in the rat striatum

21 January 2018

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Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia.

21 January 2018

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RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease.

21 January 2018

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Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function

21 January 2018

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Altered D(1) dopamine receptor trafficking in parkinsonian and dyskinetic non-human primates.

21 January 2018

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Pharmacological analysis demonstrates dramatic alteration of D1 dopamine receptor neuronal distribution in the rat analog of L-DOPA-induced dyskinesia

21 January 2018

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Enhanced preproenkephalin-B-derived opioid transmission in striatum and subthalamic nucleus converges upon globus pallidus internalis in L-3,4-dihydroxyphenylalanine-induced dyskinesia.

21 January 2018

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Differential regulation of the dopamine D2 and D3 receptors by G protein-coupled receptor kinases and beta-arrestins

21 January 2018

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Coordinated and spatial upregulation of arc in striatonigral neurons correlates with L-dopa-induced behavioral sensitization in dyskinetic rats

21 January 2018

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Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice.

28 October 2018

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D1 dopamine receptor supersensitivity in the dopamine-depleted striatum results from a switch in the regulation of ERK1/2/MAP kinase.

28 October 2018

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Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.

28 October 2018

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Molecular cloning of two rat GRK6 splice variants

28 October 2018

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D1 and D2 dopamine receptor gene expression in the rat striatum: Sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAS in distinct neuronal populations of the dorsal and ventral striatum

28 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20410529

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Arrestin2 expression selectively increases during neural differentiation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20410529

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20410529

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCITRANSLMED.3000664

1 reference

31 July 2017

1 reference

31 July 2017

1 reference