AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival (Q34106554)

31 July 2017

AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival (English)

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31 July 2017

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Ying Li

1

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31 July 2017

Donald Dowbenko

series ordinal

2

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31 July 2017

Laurence A Lasky

series ordinal

3

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31 July 2017

language of work or name

English

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publication date

27 December 2001

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Journal of Biological Chemistry

31 July 2017

10

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based on heuristic

inferred from page(s)

published in

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31 July 2017

277

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31 July 2017

13

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31 July 2017

11352-11361

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https://api.crossref.org/works/10.1074%2FJBC.M109062200

31 July 2017

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p21 is a universal inhibitor of cyclin kinases

21 January 2018

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21 January 2018

E2F-1 induced apoptosis

1 reference

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

1 reference

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

1 reference

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

21 January 2018

1 reference

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Cellular signaling: pivoting around PDK-1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109062200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109062200

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

Structural and functional similarities of prokaryotic and eukaryotic DNA polymerase sliding clamps

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

New functional activities for the p21 family of CDK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

p21(Waf1/Cip1) is an assembly factor required for platelet-derived growth factor-induced vascular smooth muscle cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

Insulin-like growth factor-mediated muscle cell survival: central roles for Akt and cyclin-dependent kinase inhibitor p21

21 January 2018

1 reference

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Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

21 January 2018

1 reference

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p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

Protective role of p21(Waf1/Cip1) against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells

21 January 2018

1 reference

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Genetic determinants of p53-induced apoptosis and growth arrest

21 January 2018

1 reference

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Reversible phosphorylation at the C-terminal regulatory domain of p21(Waf1/Cip1) modulates proliferating cell nuclear antigen binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

Phosphatidylinositol 3-kinase inhibitors, Wortmannin or LY294002, inhibited accumulation of p21 protein after gamma-irradiation by stabilization of the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

Involvement of p21 in mitotic exit after paclitaxel treatment in MCF-7 breast adenocarcinoma cell line

21 January 2018

1 reference

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Akt signaling: linking membrane events to life and death decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

Regulation of p53 stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109062200

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M109062200

1 reference

release_k34sui36j5ay5kadbohv7lysiu

31 July 2017

1 reference

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https://api.fatcat.wiki/v0/release/k34sui36j5ay5kadbohv7lysiu

mapped directly with Wikidata item

24 November 2022

based on heuristic

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