Secondary integrase resistance mutations found in HIV-1 minority quasispecies in integrase therapy-naive patients have little or no effect on susceptibility to integrase inhibitors. (Q34108775)

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English	Secondary integrase resistance mutations found in HIV-1 minority quasispecies in integrase therapy-naive patients have little or no effect on susceptibility to integrase inhibitors.	scientific article

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2 February 2020

Secondary integrase resistance mutations found in HIV-1 minority quasispecies in integrase therapy-naive patients have little or no effect on susceptibility to integrase inhibitors (English)

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2 February 2020

viral quasispecies

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2 February 2020

Loredana Sarmati

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2 February 2020

Massimo Andreoni

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2 February 2020

Carlo Federico Perno

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2 February 2020

Francesca Ceccherini-Silberstein

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Francesca Ceccherini-Silberstein

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Daniele Armenia

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Daniele Armenia

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2 February 2020

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Guido Palamara

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2 February 2020

Michela Pollicita

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2 February 2020

Maria Trignetti

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2 February 2020

Fernanda Scopelliti

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2 February 2020

Liesbeth Van Wesenbeeck

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2 February 2020

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Luca Dori

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2 February 2020

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Stefano Aquaro

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2 February 2020

Lieven J Stuyver

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Lieven J Stuyver

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2 February 2020

Kurt Van Baelen

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2 February 2020

Evelien Rondelez

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Evelien Rondelez

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2 February 2020

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Veerle Van Eygen

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2 February 2020

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17 May 2010

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2 February 2020

Antimicrobial Agents and Chemotherapy

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2 February 2020

54

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2 February 2020

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2 February 2020

3938-3948

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2 February 2020

Update of the drug resistance mutations in HIV-1: December 2009.

1 reference

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5 July 2018

Early emergence of raltegravir resistance mutations in patients receiving HAART salvage regimens

1 reference

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5 July 2018

Loss of raltegravir susceptibility by human immunodeficiency virus type 1 is conferred via multiple nonoverlapping genetic pathways

1 reference

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5 July 2018

Natural polymorphisms of human immunodeficiency virus type 1 integrase and inherent susceptibilities to a panel of integrase inhibitors

1 reference

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5 July 2018

Selective-advantage profile of human immunodeficiency virus type 1 integrase mutants explains in vivo evolution of raltegravir resistance genotypes.

1 reference

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5 July 2018

Analysis of pol integrase sequences in diverse HIV type 1 strains using a prototype genotyping assay

1 reference

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5 July 2018

Characterization and structural analysis of HIV-1 integrase conservation

1 reference

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5 July 2018

HIV-1 integrase polymorphisms are associated with prior antiretroviral drug exposure

1 reference

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5 July 2018

Potent inhibitors of HIV-1 integrase display a two-step, slow-binding inhibition mechanism which is absent in a drug-resistant T66I/M154I mutant

1 reference

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5 July 2018

Dynamic patterns of human immunodeficiency virus type 1 integrase gene evolution in patients failing raltegravir-based salvage therapies

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5 July 2018

Resistance mutations in human immunodeficiency virus type 1 integrase selected with elvitegravir confer reduced susceptibility to a wide range of integrase inhibitors

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5 July 2018

Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naïve populations and associate with reduced treatment efficacy

1 reference

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5 July 2018

Raltegravir with optimized background therapy for resistant HIV-1 infection

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5 July 2018

HIV-1 drug resistance mutations: an updated framework for the second decade of HAART

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5 July 2018

Analysis of natural sequence variation and covariation in human immunodeficiency virus type 1 integrase

1 reference

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5 July 2018

Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel

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5 July 2018

Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro

1 reference

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5 July 2018

HIV-1 integrase inhibitors: update and perspectives

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5 July 2018

Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137)

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5 July 2018

Integrase inhibitors to treat HIV/AIDS.

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5 July 2018

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

1 reference

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5 July 2018

Retroviral integrases and their cousins

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5 July 2018

More powerful procedures for multiple significance testing

1 reference

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5 July 2018

A combined genotypic and phenotypic human immunodeficiency virus type 1 recombinant virus assay for the reverse transcriptase and integrase genes

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28 October 2018

Evolution of raltegravir resistance during therapy.

1 reference

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28 October 2018

Lack of primary mutations associated with integrase inhibitors among HIV-1 subtypes B, C, and F circulating in Brazil

1 reference

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28 October 2018

Low-abundance drug-resistant viral variants in chronically HIV-infected, antiretroviral treatment-naive patients significantly impact treatment outcomes

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28 October 2018

Minority quasispecies of drug-resistant HIV-1 that lead to early therapy failure in treatment-naive and -adherent patients

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28 October 2018

Raltegravir susceptibility and fitness progression of HIV type-1 integrase in patients on long-term antiretroviral therapy.

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28 October 2018

Clade-specific HIV-1 integrase polymorphisms do not reduce raltegravir and elvitegravir phenotypic susceptibility

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28 October 2018

Natural variation of HIV-1 group M integrase: implications for a new class of antiretroviral inhibitors

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28 October 2018

Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection

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28 October 2018

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28 October 2018

Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a phase II randomised controlled trial

1 reference

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28 October 2018

Multiple mutations in human immunodeficiency virus-1 integrase confer resistance to the clinical trial drug S-1360.

1 reference

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28 October 2018

Comparative performance of high-density oligonucleotide sequencing and dideoxynucleotide sequencing of HIV type 1 pol from clinical samples.

1 reference

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28 October 2018

Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20479206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raltegravir: an integrase inhibitor for HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20479206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.01720-09

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20479206%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PMC publication ID

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2 February 2020

PubMed publication ID

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Europe PubMed Central

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2 February 2020

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