Iron overload in diabetic retinopathy: a cause or a consequence of impaired mechanisms? (Q34109492)

31 July 2017

6 references

13 March 2019

14 March 2019

24 March 2019

22 April 2019

25 April 2019

17 June 2019

Iron overload in diabetic retinopathy: a cause or a consequence of impaired mechanisms? (English)

1 reference

31 July 2017

6 references

13 March 2019

14 March 2019

24 March 2019

22 April 2019

25 April 2019

17 June 2019

6 references

13 March 2019

14 March 2019

24 March 2019

22 April 2019

25 April 2019

17 June 2019

Cristina Hernández

2

1 reference

ORCID Public Data File 2021

author name string

Andreea Ciudin

series ordinal

1

1 reference

PubMed ID

20827392

31 July 2017

Rafael Simó

series ordinal

3

1 reference

31 July 2017

8 August 2010

7 references

Experimental Diabetes Research

31 July 2017

13 March 2019

14 March 2019

24 March 2019

22 April 2019

25 April 2019

17 June 2019

7 references

31 July 2017

13 March 2019

14 March 2019

24 March 2019

22 April 2019

25 April 2019

17 June 2019

2010

1 reference

31 July 2017

535-540

1 reference

Creative Commons Attribution 3.0 Unported

31 July 2017

6 references

13 March 2019

14 March 2019

24 March 2019

22 April 2019

25 April 2019

on focus list of Wikimedia project

17 June 2019

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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5 July 2018

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Lowered cortistatin expression is an early event in the human diabetic retina and is associated with apoptosis and glial activation

5 July 2018

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Oxidative stress and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives

5 July 2018

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5 July 2018

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The protective role of transferrin in Müller glial cells after iron-induced toxicity

5 July 2018

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Role of advanced glycation end products (AGEs) and oxidative stress in diabetic retinopathy

5 July 2018

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Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy.

5 July 2018

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Prostaglandin D2 induces heme oxygenase-1 in human retinal pigment epithelial cells

5 July 2018

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Iron toxicity as a potential factor in AMD.

5 July 2018

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Iron homeostasis and toxicity in retinal degeneration

5 July 2018

1 reference

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A role for excitatory amino acids in diabetic eye disease.

5 July 2018

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Lower somatostatin expression is an early event in diabetic retinopathy and is associated with retinal neurodegeneration

5 July 2018

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Angiotensin II-induced regulation of the expression and localization of iron metabolism-related genes in the rat kidney.

5 July 2018

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5 July 2018

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RPE65 is an iron(II)-dependent isomerohydrolase in the retinoid visual cycle.

5 July 2018

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Angiotensin and diabetic retinopathy

5 July 2018

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Vascular endothelial growth factor and diabetic retinopathy: role of oxidative stress

5 July 2018

1 reference

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Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.

5 July 2018

1 reference

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Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration

5 July 2018

1 reference

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Increased expression of iron-regulating genes in monkey and human glaucoma.

5 July 2018

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Oxidative stress and redox-active iron in Alzheimer's disease

5 July 2018

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Pathogenesis of diabetic retinopathy and the renin‐angiotensin system

5 July 2018

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Important Causes of Visual Impairment in the World Today

5 July 2018

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Retinal angiogenesis is mediated by an interaction between the angiotensin type 2 receptor, VEGF, and angiopoietin

5 July 2018

1 reference

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Intracellular metal ion chelators inhibit TNFalpha-induced SP-1 activation and adhesion molecule expression in human aortic endothelial cells

5 July 2018

1 reference

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Mitochondrial ferritin: a new player in iron metabolism

5 July 2018

1 reference

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Heme oxygenase activity modulates vascular endothelial growth factor synthesis in vascular smooth muscle cells

5 July 2018

1 reference

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Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Iron and Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Chemistry and biology of eukaryotic iron metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Retinal glutamate in diabetes and effect of antioxidants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

A novel mammalian iron-regulated protein involved in intracellular iron metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

HIF-1-mediated activation of transferrin receptor gene transcription by iron chelation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Low phagocytic activity of resident peritoneal macrophages in diabetic mice: relevance to the formation of advanced glycation end products.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Suppression of cell growth by heavy chain ferritin

5 July 2018

1 reference

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A novel glycosylphosphatidylinositol-anchored form of ceruloplasmin is expressed by mammalian astrocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Neurotrophic effects of transferrin on embryonic chick brain and neural retinal cell cultures.

5 July 2018

1 reference

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Iron-sulfur clusters as biosensors of oxidants and iron

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Localization of heme oxygenase in rat retina: effect of light adaptation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Redox control of gene expression involving iron-sulfur proteins. Change of oxidation-state or assembly/disassembly of Fe-S clusters?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Reduced and oxidized ascorbates in guinea pig retina under normal and light-exposed conditions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Kinetic Studies of Ferrous Ion Oxidation with Crystalline Human Ferroxidase (Ceruloplasmin)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Renin, prorenin, and immunoreactive renin in vitreous fluid from eyes with and without diabetic retinopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Transferrin and transferrin receptor expression in intraocular proliferative disease. APAAP-immunolabeling of retinal membranes and ELISA for vitreal transferrin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Cyclic GMP-activated conductance of retinal photoreceptor cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Iron-binding proteins in the human vitreous: lactoferrin and transferrin in health and in proliferative intraocular disorders

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Role of free radicals and catalytic metal ions in human disease: an overview

5 July 2018

1 reference

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Binding to cellular receptors results in increased iron release from transferrin at mildly acidic pH.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

The Biology of Oxygen Radicals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Interphotoreceptor retinoid-binding protein (IRBP) is downregulated at early stages of diabetic retinopathy.

5 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Oxidative stress and diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Iron deposits in the central nervous system of SJL mice with experimental allergic encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Increased content of zinc and iron in human cataractous lenses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Identification of novel genes preferentially expressed in the retina using a custom human retina cDNA microarray.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Role of iron and ferritin in TNFalpha-induced apoptosis in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Inhibition of dehydroascorbic acid transport across the rat blood-retinal and -brain barriers in experimental diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Metabolic fingerprints of proliferative diabetic retinopathy: an 1H-NMR-based metabonomic approach using vitreous humor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Regulation of ferritin levels in cultured lens epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Iron regulates L-cystine uptake and glutathione levels in lens epithelial and retinal pigment epithelial cells by its effect on cytosolic aconitase

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Photoreceptor protection against light damage by AAV-mediated overexpression of heme oxygenase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Heme oxygenase in the retina in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Ischemic preconditioning of the rat retina: protective role of ferritin

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Unusual susceptibility of heme proteins to damage by glucose during non-enzymatic glycation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Selective suppression of pathologic, but not physiologic, retinal neovascularization by blocking the angiotensin II type 1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Angiotensin II receptor subtype gene expression and cellular localization in the retina and non-neuronal ocular tissues of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

High glucose-induced, endothelin-dependent fibronectin synthesis is mediated via NF-kappa B and AP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Intracellular labile iron modulates adhesion of human monocytes to human endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Iron Chelators Inhibit VCAM-1 Expression in Human Dermal Microvascular Endothelial Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Trace elements iron, copper and zinc in vitreous of patients with various vitreoretinal diseases.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

The effect of UVB irradiation on ferritin subunit synthesis, ferritin assembly and Fe metabolism in cultured canine lens epithelial cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

Impaired retinal iron homeostasis associated with defective phagocytosis in Royal College of Surgeons rats

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935195

The Role of the L-Chain in Ferritin Iron Incorporation

28 October 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F714108

Characterization of the vitreous proteome in diabetes without diabetic retinopathy and diabetes with proliferative diabetic retinopathy

21 January 2018

1 reference

12 December 2020

Colocalization of aldehyde dehydrogenases and Fe/NADPH-induced lipid peroxidation in tissue sections of rat retina

1 reference

12 December 2020

Neurons overexpressing heme oxygenase-1 resist oxidative stress-mediated cell death

1 reference

12 December 2020

Iron, ferritin, transferrin, and transferrin receptor in the adult rat retina

1 reference

12 December 2020

Induction of heme oxygenase 1 in liver of spontaneously diabetic rats

1 reference

12 December 2020

Transferrins in rabbit ocular fluids

1 reference

12 December 2020

Release of iron by human retinal pigment epithelial cells

1 reference

12 December 2020

Transferrin, one of the major vitreous proteins, is produced within the eye

1 reference

12 December 2020

Diminished heme oxygenase-1 mRNA expression in RPE cells from diabetic donors as quantitated by competitive RT/PCR

1 reference

12 December 2020

Antioxidant treatment of experimental diabetic retinopathy in rats with nicanartine

1 reference

12 December 2020

Elevated gamma-aminobutyric acid, glutamate, and vascular endothelial growth factor levels in the vitreous of patients with proliferative diabetic retinopathy

1 reference

12 December 2020

Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy. Penn State Retina Research Group

1 reference

12 December 2020

Characterization of peroxidized lipids in Bruch's membrane

1 reference

12 December 2020

HO-1 induction by HIF-1: a new mechanism for delayed cardioprotection?

1 reference

12 December 2020

The Iron Carrier Transferrin Is Upregulated in Retinas from Patients with Age-Related Macular Degeneration

1 reference

12 December 2020

Iron levels in human retina: sex difference and increase with age

1 reference

12 December 2020

Differential sensitivity of cones to iron-mediated oxidative damage

1 reference

12 December 2020

Identifiers

DOI

10.1155/2010/714108

1 reference

release_x3p4wrnbkraejpcjqf52v4amgy

31 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/x3p4wrnbkraejpcjqf52v4amgy

24 November 2022

mapped directly with Wikidata item

PMCID

2935195

1 reference

31 July 2017

1 reference

PubMed ID

20827392