Epigenetic silencing of IRF7 and/or IRF5 in lung cancer cells leads to increased sensitivity to oncolytic viruses (Q34110261)

31 July 2017

Epigenetic silencing of IRF7 and/or IRF5 in lung cancer cells leads to increased sensitivity to oncolytic viruses (English)

1 reference

31 July 2017

1 reference

1 reference

Qunfang Li

1

1 reference

PubMed ID

22194884

31 July 2017

Michael A Tainsky

series ordinal

2

1 reference

PubMed ID

22194884

31 July 2017

language of work or name

English

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publication date

14 December 2011

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31 July 2017

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31 July 2017

6

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31 July 2017

12

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31 July 2017

e28683

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Creative Commons Attribution 4.0 International

31 July 2017

start time

14 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Oncolytic Viruses for Cancer Therapy: Overcoming the Obstacles

5 July 2018

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DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae

5 July 2018

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Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production

5 July 2018

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Down-regulation of type I interferon receptor sensitizes bladder cancer cells to vesicular stomatitis virus-induced cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Reduced expression of IRF7 in nasal epithelial cells from smokers after infection with influenza

5 July 2018

1 reference

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Engineering oncolytic viruses to exploit tumor specific defects in innate immune signaling pathways

5 July 2018

1 reference

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Epigenetics in cancer: targeting chromatin modifications

5 July 2018

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Expression of RIG-I, IRF3, IFN-beta and IRF7 determines resistance or susceptibility of cells to infection by Newcastle Disease Virus.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Enhancement of oncolytic properties of recombinant newcastle disease virus through antagonism of cellular innate immune responses

5 July 2018

1 reference

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Identification of genes epigenetically silenced by CpG methylation in human gastric carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Epigenetic regulation and molecular characterization of C/EBPalpha in pancreatic cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Interferon regulatory factors IRF5 and IRF7 inhibit growth and induce senescence in immortal Li-Fraumeni fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Impaired IFN-alpha production and the risk of cancer development

5 July 2018

1 reference

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DNA methylation as a therapeutic target in cancer

5 July 2018

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An infectious retrovirus susceptible to an IFN antiviral pathway from human prostate tumors

5 July 2018

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Variable deficiencies in the interferon response enhance susceptibility to vesicular stomatitis virus oncolytic actions in glioblastoma cells but not in normal human glial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Interferons, immunity and cancer immunoediting

5 July 2018

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Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle, and cytoskeleton.

5 July 2018

1 reference

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Differentially regulated interferon response determines the outcome of Newcastle disease virus infection in normal and tumor cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Microarray analysis of promoter methylation in lung cancers.

5 July 2018

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Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Interferon resistance promotes oncolysis by influenza virus NS1-deletion mutants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Interferon regulatory factor 5, a novel mediator of cell cycle arrest and cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Development of recombinant vesicular stomatitis viruses that exploit defects in host defense to augment specific oncolytic activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Genetically engineered vesicular stomatitis virus in gene therapy: application for treatment of malignant disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or myc function and involves the induction of apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

IFN-beta induces serine phosphorylation of Stat-1 in Ewing's sarcoma cells and mediates apoptosis via induction of IRF-1 and activation of caspase-7

5 July 2018

1 reference

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Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Human bronchial epithelial cells with integrated SV40 virus T antigen genes retain the ability to undergo squamous differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3237484

Epigenetic silencing of multiple interferon pathway genes after cellular immortalization.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028683

Methylation profiling of twenty four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028683

De novo methylation of an embryonic globin gene during normal development is strand specific and spreads from the proximal transcribed region

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028683

Phase I trial of intravenous administration of PV701, an oncolytic virus, in patients with advanced solid cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028683

An optimized clinical regimen for the oncolytic virus PV701.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028683

Oncolytic viruses move forward in clinical trials

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22194884

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enhanced tumor development in mice lacking a functional type I interferon receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22194884

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0028683

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference

PubMed ID

22194884