Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance (Q34112635)

31 July 2017

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance (English)

1 reference

Pablo Blanco Martínez de Morentín

31 July 2017

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Vidya R Velagapudi

6

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Pablo Blanco Martínez de Morentin

11

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Sulay Tovar

Sulay Tovar

12

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Asish K Saha

Asish K Saha

19

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David Carling

David Carling

14

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Kamal Rahmouni

Kamal Rahmouni

20

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Miguel López

Miguel López

1

0 references

Ruben Nogueiras

Rubén Nogueiras

13

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Matej Orešič

Matej Oresic

17

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Antonio Vidal-Puig

Antonio Vidal-Puig

22

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author name string

Luis Varela

2

1 reference

31 July 2017

María J Vázquez

3

1 reference

31 July 2017

Sergio Rodríguez-Cuenca

4

1 reference

31 July 2017

Carmen R González

5

1 reference

31 July 2017

Donald A Morgan

7

1 reference

31 July 2017

Erik Schoenmakers

8

1 reference

31 July 2017

Khristofor Agassandian

9

1 reference

31 July 2017

Ricardo Lage

10

1 reference

31 July 2017

Christopher Lelliott

15

1 reference

31 July 2017

Rosalía Gallego

16

1 reference

31 July 2017

Krishna Chatterjee

18

1 reference

31 July 2017

Carlos Diéguez

21

1 reference

31 July 2017

language of work or name

English

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publication date

29 August 2010

1 reference

31 July 2017

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31 July 2017

16

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31 July 2017

1001-1008

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31 July 2017

9

1 reference

https://scigraph.springernature.com/pub.10.1038/nm.2207

31 July 2017

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cites work

Ghrelin effects on neuropeptides in the rat hypothalamus depend on fatty acid metabolism actions on BSX but not on gender

1 reference

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Hypothalamic thyroid hormone in energy balance regulation.

5 July 2018

1 reference

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Thyroid hormone induced brown adipose tissue and amelioration of diabetes in a patient with extreme insulin resistance

5 July 2018

1 reference

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The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake

5 July 2018

1 reference

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Functional brown adipose tissue in healthy adults

5 July 2018

1 reference

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Identification and importance of brown adipose tissue in adult humans

5 July 2018

1 reference

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Cold-activated brown adipose tissue in healthy men

5 July 2018

1 reference

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AMPK: a metabolic gauge regulating whole-body energy homeostasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Unexpected evidence for active brown adipose tissue in adult humans

5 July 2018

1 reference

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A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Hypothalamic sensing of fatty acids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Hypothalamic PI3K and MAPK differentially mediate regional sympathetic activation to insulin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Brown adipose tissue: function and physiological significance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Hypothalamic malonyl-CoA as a mediator of feeding behavior

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Long-term regulation of AMP-activated protein kinase and acetyl-CoA carboxylase in skeletal muscle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Effects of thyroid state on AMP-activated protein kinase and acetyl-CoA carboxylase expression in muscle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Central leptin regulates the UCP1 and ob genes in brown and white adipose tissue via different beta-adrenoceptor subtypes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Thyroid hormone control of thermogenesis and energy balance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Turnover and splanchnic metabolism of free fatty acids in hyperthyroid patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Role of ventromedial hypothalamus on sympathetic efferents of brown adipose tissue.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Fatty acid synthetase of brain: development, influence of nutritional and hormonal factors and comparison with liver enzyme.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Brown adipose tissue thermogenesis is activated by electrical and chemical (L-glutamate) stimulation of the ventromedial hypothalamic nucleus in cold-acclimated rats.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Thyroid hormone resistance syndrome. Inhibition of normal receptor function by mutant thyroid hormone receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Differential action of thyroid hormones on the activity of certain enzymes in rat kidney and brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Tissue-specific regulation of fatty acid synthesis by thyroid hormone

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Neuronal regulation of homeostasis by nutrient sensing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Influence of ghrelin and growth hormone deficiency on AMP-activated protein kinase and hypothalamic lipid metabolism.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Thyroid hormone effects on LKB1, MO25, phospho-AMPK, phospho-CREB, and PGC-1alpha in rat muscle

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Thyroid hormone (T3) rapidly activates p38 and AMPK in skeletal muscle in vivo.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Molecular disruption of hypothalamic nutrient sensing induces obesity.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Elevated regional lipolysis in hyperthyroidism

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Food choice in hyperthyroidism: potential influence of the autonomic nervous system and brain serotonin precursor availability.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Hepatic lipogenesis and cholesterol synthesis in hyperthyroid patients

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935934

Biomedicine. A sympathetic defense against obesity

28 October 2018

1 reference

12 December 2020

Effect of hyperthyroidism on lipogenesis in brown adipose tissue of young rats

1 reference

12 December 2020

Hypothalamic control of brown adipose tissue in Zucker lean and obese rats. Effect of electrical stimulation of the ventromedial nucleus and other hypothalamic centres

1 reference

12 December 2020

Lipolytic and ketogenic fluxes in human hyperthyroidism

1 reference

12 December 2020

Tissue-specific regulation of lipogenic mRNAs by thyroid hormone

1 reference

12 December 2020

The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity

1 reference

7 January 2021

AMP-activated protein kinase signaling in metabolic regulation

1 reference

7 January 2021

KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity

1 reference

7 January 2021

AMPK beta1 deletion reduces appetite, preventing obesity and hepatic insulin resistance

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM.2207

1 reference

31 July 2017

1 reference

31 July 2017

1 reference