Remodelling of the natural product fumagillol employing a reaction discovery approach (Q34116181)

31 July 2017

title

Remodelling of the natural product fumagillol employing a reaction discovery approach (English)

1 reference

31 July 2017

1 reference

4

John A Porco

1 reference

31 July 2017

Bradley R Balthaser

1

1 reference

31 July 2017

Meghan C Maloney

series ordinal

2

1 reference

31 July 2017

Aaron B Beeler

series ordinal

3

1 reference

31 July 2017

John K Snyder

series ordinal

5

1 reference

31 July 2017

publication date

1 December 2011

1 reference

31 July 2017

1 reference

31 July 2017

volume

3

1 reference

31 July 2017

issue

12

1 reference

31 July 2017

page(s)

969-973

1 reference

Multidimensional Screening and Methodology Development for Condensations Involving Complex 1,2-Diketones

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]-9H-purine.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

N-Alkyl-octahydroisoquinolin-1-one-8-carboxamides: a Novel Class of Selective, Nonbasic, Nitrogen-Containing κ-Opioid Receptor Ligands

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Skeletal diversity via cationic rearrangements of substituted dihydropyrans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Synthesis of unique scaffolds via Diels-Alder cycloadditions of tetrasubstituted cyclohexadienes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Syntheses of fumagillin and ovalicin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

An approach to the site-selective diversification of apoptolidin A with peptide-based catalysts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Reaction discovery employing macrocycles: transannular cyclizations of macrocyclic bis-lactams

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Anticancer activity of (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Cinnamoyl derivatives of 7alpha-aminomethyl-6,14-endo-ethanotetrahydrothebaine and 7alpha-aminomethyl-6,14-endo-ethanotetrahydrooripavine and related opioid ligands

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Natural products in parallel chemistry--novel 5-lipoxygenase inhibitors from BIOS-based libraries starting from alpha-santonin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Discovery of chemical reactions through multidimensional screening

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Natural products in combinatorial chemistry: an andrographolide-based library

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Investigation of novel fumagillin analogues as angiogenesis inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

An Enantioselective Synthesis of Cis Perhydroisoquinoline LY235959.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Multivariate data analysis using D-optimal designs, partial least squares, and response surface modeling: A directional approach for the analysis of farnesyltransferase inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Structure of human methionine aminopeptidase-2 complexed with fumagillin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3254213

Escape from flatland: increasing saturation as an approach to improving clinical success

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1178

Evolution of natural product scaffolds by acyl- and arylnitroso hetero-diels-alder reactions: new chemistry on piperine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1178

Potent, brain-penetrant, hydroisoindoline-based human neurokinin-1 receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1178

Design, synthesis and evaluation of a series of novel fumagillin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1178

Pt(II)-catalyzed synthesis of 9-oxabicyclo[3.3.1]nona-2,6-dienes from 2-alkynyl-1-carbonylbenzenes and allylsilanes by an allylation/annulation cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1178

An expeditious synthesis of bruguierol A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1178

Site-Selective Derivatization and Remodeling of Erythromycin A by Using Simple Peptide-Based Chiral Catalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1178

Effective, selective hydroalkoxylation/cyclization of alkynyl and allenyl alcohols mediated by lanthanide catalysts

21 January 2018

1 reference

12 December 2020

Unnatural Natural Products from the Transannular Cyclization of Lathyrane Diterpenes

1 reference

12 December 2020

Gold- or platinum-catalyzed cascade processes of alkynol derivatives involving hydroalkoxylation reactions followed by Prins-type cyclizations

1 reference

12 December 2020

Importance of the hydrophobie energy: Structural determination of a hypoglycemie drug of the meglitinide family by nuclear magnetic resonance and molecular modeling

1 reference

12 December 2020

Tandem intramolecular hydroalkoxylation-hydroarylation reactions: synthesis of enantiopure benzofused cyclic ethers from the chiral pool

1 reference

12 December 2020

Fumarranol, a rearranged fumagillin analogue that inhibits angiogenesis in vivo

1 reference

12 December 2020

Ring-opening and ring-closing reactions of a shikimic acid-derived substrate leading to diverse small molecules

1 reference

12 December 2020

Iminonitroso Diels-Alder reactions for efficient derivatization and functionalization of complex diene-containing natural products

1 reference

12 December 2020

Substituent activity relationship studies on new azolo benzoxazepinyl oxazolidinones

1 reference

12 December 2020

The Chemistry of Fumagillin1

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1178

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCHEM.1178

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference

31 July 2017

1 reference