The spindle: a dynamic assembly of microtubules and motors (Q34123567)

31 July 2017

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title

The spindle: a dynamic assembly of microtubules and motors (English)

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31 July 2017

Wittmann T

1

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31 July 2017

Hyman A

series ordinal

2

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31 July 2017

Desai A

series ordinal

3

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31 July 2017

1 January 2001

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31 July 2017

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31 July 2017

3

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31 July 2017

E28-34

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31 July 2017

1

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https://scigraph.springernature.com/pub.10.1038/35050669

31 July 2017

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The 4 A X-ray structure of a tubulin:stathmin-like domain complex

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Mutational analysis of op18/stathmin-tubulin-interacting surfaces. Binding cooperativity controls tubulin GTP hydrolysis in the ternary complex

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Dissociation of the tubulin-sequestering and microtubule catastrophe-promoting activities of oncoprotein 18/stathmin

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Op18/stathmin mediates multiple region-specific tubulin and microtubule-regulating activities

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Dynamics of centromeres during metaphase-anaphase transition in fission yeast: Dis1 is implicated in force balance in metaphase bipolar spindle

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ZYG-9, a Caenorhabditis elegans protein required for microtubule organization and function, is a component of meiotic and mitotic spindle poles

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A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end

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XMAP from Xenopus eggs promotes rapid plus end assembly of microtubules and rapid microtubule polymer turnover.

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Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts

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Phosphorylation by CDK1 regulates XMAP215 function in vitro

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Poleward microtubule flux mitotic spindles assembled in vitro

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The kinetochore microtubule minus-end disassembly associated with poleward flux produces a force that can do work

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A switch in microtubule dynamics at the onset of anaphase B in the mitotic spindle of Schizosaccharomyces pombe

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Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts

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Spindle assembly in Xenopus egg extracts: respective roles of centrosomes and microtubule self-organization

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Anaphase A chromosome movement and poleward spindle microtubule flux occur At similar rates in Xenopus extract spindles

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Dynein intermediate chain mediated dynein-dynactin interaction is required for interphase microtubule organization and centrosome replication and separation in Dictyostelium

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Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo

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Cytoplasmic dynein and dynactin in cell division and intracellular transport

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Functional coordination of three mitotic motors in Drosophila embryos

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Cytoplasmic dynein is required for the nuclear attachment and migration of centrosomes during mitosis in Drosophila

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Centrosome-independent mitotic spindle formation in vertebrates

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A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity.

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Respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase

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The ran GTPase regulates mitotic spindle assembly.

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7 January 2021

Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran

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7 January 2021

Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran

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Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation

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The dynein microtubule motor

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7 January 2021

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The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles

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Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

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Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

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Saccharomyces cerevisiae kinesin- and dynein-related proteins required for anaphase chromosome segregation

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7 January 2021

Xklp1, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning.

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7 January 2021

Self-organization of microtubules and motors.

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7 January 2021

A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly.

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7 January 2021

Formation of spindle poles by dynein/dynactin-dependent transport of NuMA

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7 January 2021

Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein

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7 January 2021

Taxol-induced microtubule asters in mitotic extracts of Xenopus eggs: requirement for phosphorylated factors and cytoplasmic dynein

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7 January 2021

NuMA is a component of an insoluble matrix at mitotic spindle poles

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7 January 2021

Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice

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7 January 2021

TPX2, A novel xenopus MAP involved in spindle pole organization

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7 January 2021

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7 January 2021

Xklp2, a novel Xenopus centrosomal kinesin-like protein required for centrosome separation during mitosis.

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7 January 2021

Spindle assembly and mitosis without centrosomes in parthenogenetic Sciara embryos

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7 January 2021

Mutations in centrosomin reveal requirements for centrosomal function during early Drosophila embryogenesis.

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7 January 2021

Molecular linkage underlying microtubule orientation toward cortical sites in yeast

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7 January 2021

Myosin V orientates the mitotic spindle in yeast

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7 January 2021

Positioning of the mitotic spindle by a cortical-microtubule capture mechanism

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7 January 2021

Checkpoints controlling mitosis

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7 January 2021

Kinetochores moving away from their associated pole do not exert a significant pushing force on the chromosome

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7 January 2021

Kinetochores are transported poleward along a single astral microtubule during chromosome attachment to the spindle in newt lung cells

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7 January 2021

Oscillatory movements of monooriented chromosomes and their position relative to the spindle pole result from the ejection properties of the aster and half-spindle

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7 January 2021

Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis

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7 January 2021

CENP-E is a putative kinetochore motor that accumulates just before mitosis

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7 January 2021

Localization of cytoplasmic dynein to mitotic spindles and kinetochores

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7 January 2021

Cytoplasmic dynein is localized to kinetochores during mitosis

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7 January 2021

Dynein is a transient kinetochore component whose binding is regulated by microtubule attachment, not tension

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7 January 2021

Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis

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7 January 2021

Cytoplasmic dynein is required for poleward chromosome movement during mitosis in Drosophila embryos

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7 January 2021

The rate of poleward chromosome motion is attenuated in Drosophila zw10 and rod mutants.

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7 January 2021

CENP-E function at kinetochores is essential for chromosome alignment.

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7 January 2021

CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment

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7 January 2021

CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila

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7 January 2021

CENP-E as an essential component of the mitotic checkpoint in vitro.

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7 January 2021

CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint

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7 January 2021

Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro

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7 January 2021

Mitotic centromere-associated kinesin is important for anaphase chromosome segregation

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7 January 2021

Meiotic spindle assembly in Drosophila females: behavior of nonexchange chromosomes and the effects of mutations in the nod kinesin-like protein.

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7 January 2021

The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement

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7 January 2021

Xkid, a chromokinesin required for chromosome alignment on the metaphase plate

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7 January 2021

Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1

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7 January 2021

Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

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7 January 2021

Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase

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7 January 2021

Poleward kinetochore fiber movement occurs during both metaphase and anaphase-A in newt lung cell mitosis

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7 January 2021

The forces that move chromosomes in mitosis

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7 January 2021

Identifiers

DOI

10.1038/35050669

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Dimensions Publication ID

31 July 2017

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