Amino acid mutations essential to production of an altered PBP 2X conferring high-level beta-lactam resistance in a clinical isolate of Streptococcus pneumoniae (Q34123698)

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English	Amino acid mutations essential to production of an altered PBP 2X conferring high-level beta-lactam resistance in a clinical isolate of Streptococcus pneumoniae	scientific article

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scholarly article

1 reference

Europe PubMed Central

31 July 2017

Amino acid mutations essential to production of an altered PBP 2X conferring high-level beta-lactam resistance in a clinical isolate of Streptococcus pneumoniae (English)

1 reference

Europe PubMed Central

31 July 2017

Streptococcus pneumoniae

1 reference

based on heuristic

inferred from title

Keith P. Klugman

2

object named as

Keith P Klugman

1 reference

Europe PubMed Central

31 July 2017

author name string

Anthony M Smith

1

1 reference

Europe PubMed Central

31 July 2017

language of work or name

0 references

publication date

1 November 2005

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Europe PubMed Central

31 July 2017

Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

31 July 2017

49

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Europe PubMed Central

31 July 2017

11

1 reference

Europe PubMed Central

31 July 2017

4622-4627

1 reference

Europe PubMed Central

31 July 2017

Altered PBP 2A and its role in the development of penicillin, cefotaxime, and ceftriaxone resistance in a clinical isolate of Streptococcus pneumoniae.

1 reference

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5 July 2018

The structural modifications induced by the M339F substitution in PBP2x from Streptococcus pneumoniae further decreases the susceptibility to beta-lactams of resistant strains

1 reference

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5 July 2018

Alterations in MurM, a cell wall muropeptide branching enzyme, increase high-level penicillin and cephalosporin resistance in Streptococcus pneumoniae

1 reference

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The crystal structure of the penicillin-binding protein 2x from Streptococcus pneumoniae and its acyl-enzyme form: implication in drug resistance

1 reference

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Inhibition of the expression of penicillin resistance in Streptococcus pneumoniae by inactivation of cell wall muropeptide branching genes.

1 reference

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5 July 2018

Identification of a structural determinant for resistance to beta-lactam antibiotics in Gram-positive bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280142

5 July 2018

Alterations in PBP 1A essential-for high-level penicillin resistance in Streptococcus pneumoniae.

1 reference

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Acquisition of five high-Mr penicillin-binding protein variants during transfer of high-level beta-lactam resistance from Streptococcus mitis to Streptococcus pneumoniae

1 reference

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A mutation in the D,D-carboxypeptidase penicillin-binding protein 3 of Streptococcus pneumoniae contributes to cefotaxime resistance of the laboratory mutant C604.

1 reference

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In vitro selection of one-step mutants of Streptococcus pneumoniae resistant to different oral beta-lactam antibiotics is associated with alterations of PBP2x

1 reference

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Genetic diversity of penicillin-binding protein 2B and 2X genes from Streptococcus pneumoniae in South Africa

1 reference

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Genetic analysis of clinical isolates of Streptococcus pneumoniae with high-level resistance to expanded-spectrum cephalosporins

1 reference

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Multiple changes of penicillin-binding proteins in penicillin-resistant clinical isolates of Streptococcus pneumoniae

1 reference

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Penicillin-binding proteins of multiply antibiotic-resistant South African strains of Streptococcus pneumoniae

1 reference

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5 July 2018

Horizontal transfer of penicillin-binding protein genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280142

5 July 2018

Five independent combinations of mutations can result in low-affinity penicillin-binding protein 2x of Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280142

5 July 2018

Interspecies recombinational events during the evolution of altered PBP 2x genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280142

5 July 2018

Genetics of resistance to third-generation cephalosporins in clinical isolates of Streptococcus pneumoniae.

1 reference

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5 July 2018

Relatedness of penicillin-binding protein 1a genes from different clones of penicillin-resistant Streptococcus pneumoniae isolated in South Africa and Spain

1 reference

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5 July 2018

Growth and division of Streptococcus pneumoniae: localization of the high molecular weight penicillin‐binding proteins during the cell cycle

1 reference

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28 October 2018

A technique permitting selection of penicillin-susceptible pneumococcal strains following transformation of a penicillin-resistant strain with a penicillin-susceptibility gene

1 reference

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Non-Penicillin-Binding protein mediated high-level penicillin and cephalosporin resistance in a Hungarian clone of Streptococcus pneumoniae

1 reference

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28 October 2018

The fib locus in Streptococcus pneumoniae is required for peptidoglycan crosslinking and PBP-mediated beta-lactam resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280142

28 October 2018

Mutations in the active site of penicillin-binding protein PBP2x from Streptococcus pneumoniae. Role in the specificity for beta-lactam antibiotics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280142

28 October 2018

Unconventional organization of the division and cell wall gene cluster of Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280142

28 October 2018

Penicillin-binding proteins as resistance determinants in clinical isolates of Streptococcus pneumoniae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280142

28 October 2018

Deletion analysis of the essentiality of penicillin-binding proteins 1A, 2B and 2X of Streptococcus pneumoniae.

1 reference

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28 October 2018

Genetics of high level penicillin resistance in clinical isolates of Streptococcus pneumoniae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1280142

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Intra- and inter-specific transformation of Streptococcus pneumoniae to penicillin resistance

1 reference

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Penicillin-binding proteins 2x and 2b as primary PBP targets in Streptococcus pneumoniae

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251304

12 December 2020

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10.1128/AAC.49.11.4622-4627.2005

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Europe PubMed Central

31 July 2017

release_t4vpvg4zvrai5opfv5tig4tr6e

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24 November 2022

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Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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