An osteoblast-derived proteinase controls tumor cell survival via TGF-beta activation in the bone microenvironment (Q34125314)

31 July 2017

An osteoblast-derived proteinase controls tumor cell survival via TGF-beta activation in the bone microenvironment (English)

1 reference

31 July 2017

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Barbara Mary Fingleton

object named as

Barbara Fingleton

3

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author name string

Sophie Thiolloy

1

1 reference

31 July 2017

James R Edwards

2

1 reference

31 July 2017

Daniel B Rifkin

4

1 reference

31 July 2017

Lynn M Matrisian

5

1 reference

31 July 2017

Conor C Lynch

6

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31 July 2017

language of work or name

English

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publication date

4 January 2012

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31 July 2017

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31 July 2017

7

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31 July 2017

1

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31 July 2017

e29862

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Creative Commons Attribution 4.0 International

31 July 2017

start time

4 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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TGF-β in cancer and bone: implications for treatment of bone metastases

5 July 2018

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Matrix metalloproteinases as master regulators of the vicious cycle of bone metastasis

5 July 2018

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Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics

5 July 2018

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Mutations in LTBP4 cause a syndrome of impaired pulmonary, gastrointestinal, genitourinary, musculoskeletal, and dermal development

5 July 2018

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Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis

5 July 2018

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Molecular mechanisms in coupling of bone formation to resorption.

5 July 2018

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Advancing treatment for metastatic bone cancer: consensus recommendations from the Second Cambridge Conference

5 July 2018

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Effect of ablation or inhibition of stromal matrix metalloproteinase-9 on lung metastasis in a breast cancer model is dependent on genetic background

5 July 2018

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EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblasts

5 July 2018

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Host matrix metalloproteinase-9 contributes to tumor vascularization without affecting tumor growth in a model of prostate cancer bone metastasis

5 July 2018

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The application of a murine bone bioreactor as a model of tumor: bone interaction

5 July 2018

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BMP1 controls TGFbeta1 activation via cleavage of latent TGFbeta-binding protein

5 July 2018

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Activated type I TGFbeta receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression

5 July 2018

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Transforming growth factor-beta1 to the bone

5 July 2018

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Osteopetrosis-like phenotype in latent TGF-beta binding protein 3 deficient mice

5 July 2018

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Proliferative effects of apical, but not basal, matrix metalloproteinase-7 activity in polarized MDCK cells.

5 July 2018

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Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung

5 July 2018

1 reference

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Pro-matrix metalloproteinase-2 transfection increases orthotopic primary growth and experimental metastasis of MDA-MB-231 human breast cancer cells in nude mice

5 July 2018

1 reference

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MT1-MMP-dependent, apoptotic remodeling of unmineralized cartilage: a critical process in skeletal growth

5 July 2018

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Transforming Growth Factor-Beta in Osteolytic Breast Cancer Bone Metastases

5 July 2018

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Mechanisms of osteolytic bone metastases in breast carcinoma

5 July 2018

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Bone defects in latent TGF-beta binding protein (Ltbp)-3 null mice; a role for Ltbp in TGF-beta presentation

5 July 2018

1 reference

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Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Metastasis to bone: causes, consequences and therapeutic opportunities

5 July 2018

1 reference

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Secretion of human latent TGF-beta-binding protein-3 (LTBP-3) is dependent on co-expression of TGF-beta

5 July 2018

1 reference

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Bone marrow and bone: a functional unit

5 July 2018

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Latent TGF-beta binding protein-3 (LTBP-3) requires binding to TGF-beta for secretion

5 July 2018

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The first stage of transforming growth factor beta1 activation is release of the large latent complex from the extracellular matrix of growth plate chondrocytes by matrix vesicle stromelysin-1 (MMP-3)

5 July 2018

1 reference

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Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability

5 July 2018

1 reference

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Transforming growth factor beta affects osteoclast differentiation via direct and indirect actions.

5 July 2018

1 reference

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Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Bone resorption by osteoclasts

5 July 2018

1 reference

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Molecular mechanisms of osteolytic bone metastases

5 July 2018

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Latent transforming growth factor-beta binding proteins (LTBPs)--structural extracellular matrix proteins for targeting TGF-beta action

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

5 July 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Proteinases in bone resorption: obvious and less obvious roles.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Inhibition of TGF-beta receptor signaling in osteoblasts leads to decreased bone remodeling and increased trabecular bone mass.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Mechanisms for pro matrix metalloproteinase activation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Induction of matrix metalloproteinase activation cascades based on membrane-type 1 matrix metalloproteinase: associated activation of gelatinase A, gelatinase B and collagenase 3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Processing of transforming growth factor beta 1 precursor by human furin convertase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Dual role for the latent transforming growth factor-beta binding protein in storage of latent TGF-beta in the extracellular matrix and as a structural matrix protein.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Characterization of insulin-like growth factor-binding protein 5-degrading proteases produced throughout murine osteoblast differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

The release of collagenase as an inactive proenzyme by bone explants in culture

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

The clinical course of bone metastases from breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251607

The metalloproteinase MT1-MMP is required for normal development and maintenance of osteocyte processes in bone.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029862

A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029862

Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029862

MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029862

Proteolysis of latent transforming growth factor-beta (TGF-beta )-binding protein-1 by osteoclasts. A cellular mechanism for release of TGF-beta from bone matrix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029862

Proteomics discovery of metalloproteinase substrates in the cellular context by iTRAQ labeling reveals a diverse MMP-2 substrate degradome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029862

Matrix metalloproteinase 9 (MMP-9/gelatinase B) proteolytically cleaves ICAM-1 and participates in tumor cell resistance to natural killer cell-mediated cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029862

Activation of latent transforming growth factor beta1 by stromelysin 1 in extracts of growth plate chondrocyte-derived matrix vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029862

Transforming growth factor-beta1 abrogates Fas-induced growth suppression and apoptosis of murine bone marrow progenitor cells

21 January 2018

1 reference

12 December 2020

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice

1 reference

12 December 2020

Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor

1 reference

12 December 2020

The autocrine production of transforming growth factor-beta 1 during lymphocyte activation. A study with a monoclonal antibody-based ELISA

1 reference

12 December 2020

Stromelysin (MMP-3) synthesis is up-regulated in estrogen-deficient mouse osteoblasts in vivo and in vitro

1 reference

12 December 2020

Long form of latent TGF- binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0029862

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DOI

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31 July 2017

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31 July 2017

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