Cell culture processes for monoclonal antibody production (Q34125491)

31 July 2017

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title

Cell culture processes for monoclonal antibody production (English)

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31 July 2017

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Feng Li

1

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31 July 2017

Natarajan Vijayasankaran

2

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31 July 2017

Amy Yijuan Shen

3

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31 July 2017

Robert Kiss

4

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31 July 2017

Ashraf Amanullah

5

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31 July 2017

publication date

1 September 2010

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31 July 2017

published in

Monoclonal Antibodies

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31 July 2017

volume

2

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31 July 2017

issue

5

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31 July 2017

page(s)

466-479

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Alteration of mammalian cell metabolism by dynamic nutrient feeding

31 July 2017

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Protein-free fed-batch culture of non-GS NS0 cell lines for production of recombinant antibodies

5 July 2018

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Derivation and characterization of cholesterol-independent non-GS NS0 cell lines for production of recombinant antibodies

5 July 2018

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5 July 2018

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The use of recombinase mediated cassette exchange in retroviral vector producer cell lines: predictability and efficiency by transgene exchange

5 July 2018

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Effects of lactate dehydrogenase suppression and glycerol-3-phosphate dehydrogenase overexpression on cellular metabolism

5 July 2018

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Reverting cholesterol auxotrophy of NS0 cells by altering epigenetic gene silencing

5 July 2018

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5 July 2018

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Production of recombinant protein therapeutics in cultivated mammalian cells

5 July 2018

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Characterizing biological products and assessing comparability following manufacturing changes.

5 July 2018

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A detailed understanding of the enhanced hypothermic productivity of interferon-gamma by Chinese-hamster ovary cells

5 July 2018

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Production technologies for monoclonal antibodies and their fragments

5 July 2018

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Characterization of humanized antibodies secreted by Aspergillus niger

5 July 2018

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Uncoupling of cell growth and proliferation results in enhancement of productivity in p21CIP1-arrested CHO cells.

5 July 2018

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Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid

5 July 2018

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High-level expression of recombinant IgG in the human cell line per.c6.

5 July 2018

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5 July 2018

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A study of immunoglobulin G glycosylation in monoclonal and polyclonal species by electrospray and matrix-assisted laser desorption/ionization mass spectrometry

5 July 2018

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Characterization of hybridoma cell responses to elevated pCO(2) and osmolality: intracellular pH, cell size, apoptosis, and metabolism

5 July 2018

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Expression of GnTIII in a recombinant anti-CD20 CHO production cell line: Expression of antibodies with altered glycoforms leads to an increase in ADCC through higher affinity for FC gamma RIII.

5 July 2018

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The human cell line PER.C6 provides a new manufacturing system for the production of influenza vaccines.

5 July 2018

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Engineering of a mammalian cell line for reduction of lactate formation and high monoclonal antibody production

5 July 2018

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5 July 2018

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5 July 2018

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The production of monoclonal antibody in growth-arrested hybridomas cultivated in suspension and immobilized modes

5 July 2018

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5 July 2018

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Glycosylation of CHO-derived recombinant tPA produced under elevated pCO2.

5 July 2018

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5 July 2018

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Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

5 July 2018

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Effects of dissolved oxygen concentration on hybridoma growth and metabolism in continuous culture

5 July 2018

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A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

5 July 2018

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5 July 2018

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Application of a statistical design to the optimization of culture medium for recombinant interferon-gamma production by Chinese hamster ovary cells

5 July 2018

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Effects of dissolved oxygen on hybridoma cell growth, metabolism, and antibody production kinetics in continuous culture

5 July 2018

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5 July 2018

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Anti-N-glycolylneuraminic acid antibodies identified in healthy human serum

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Identification of cell culture conditions to control N-glycosylation site-occupancy of recombinant glycoproteins expressed in CHO cells.

21 January 2018

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21 January 2018

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Dissolved oxygen concentration in serum-free continuous culture affects N-linked glycosylation of a monoclonal antibody.

21 January 2018

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Dissolved carbon dioxide accumulation in a large scale and high density production of TGFβ receptor with baculovirus infected Sf-9 cells

21 January 2018

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Effects of elevated pCO2 and osmolality on growth of CHO cells and production of antibody-fusion protein B1: a case study

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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A predictive high-throughput scale-down model of monoclonal antibody production in CHO cells.

21 January 2018

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Simultaneous measurement of 19 components in serum-containing animal cell culture media by fourier transform near-infrared spectroscopy.

21 January 2018

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Design and performance of a 24-station high throughput microbioreactor.

21 January 2018

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Toward genomic cell culture engineering

21 January 2018

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Cell culture monitoring via an auto-sampler and an integrated multi-functional off-line analyzer

21 January 2018

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CO(2) in large-scale and high-density CHO cell perfusion culture

28 October 2018

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12 December 2020

Growth of NS0 cells in protein-free, chemically defined medium

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12 December 2020

High cell density and high monoclonal antibody production through medium design and rational control in a bioreactor

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12 December 2020

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12 December 2020

Rapid calibration of near-infrared spectroscopic measurements of mammalian cell cultivations

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12 December 2020

International Conference on Harmonisation; guidance on Q5E Comparability of Biotechnological/Biological Products Subject to Changes in Their Manufacturing Process; availability. Notice

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Identifiers

DOI

10.4161/MABS.2.5.12720

1 reference

31 July 2017

1 reference

31 July 2017

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