A functional genomic screen in planarians identifies novel regulators of germ cell development (Q34127490)

31 July 2017

A functional genomic screen in planarians identifies novel regulators of germ cell development (English)

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31 July 2017

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Yuying Wang

1

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31 July 2017

Joel M Stary

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2

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31 July 2017

James E Wilhelm

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3

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31 July 2017

Phillip A Newmark

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4

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31 July 2017

1 September 2010

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31 July 2017

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31 July 2017

24

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31 July 2017

18

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31 July 2017

2081-2092

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describes a project that uses

31 July 2017

limma

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22 June 2022

https://europepmc.org/article/PMC/2939369

inferred from PubMed Central ID database lookup

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The RNA-binding protein NANOS2 is required to maintain murine spermatogonial stem cells

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The PIWI proteins SMEDWI-2 and SMEDWI-3 are required for stem cell function and piRNA expression in planarians.

5 July 2018

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Beta-catenin defines head versus tail identity during planarian regeneration and homeostasis

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Controls of germline stem cells, entry into meiosis, and the sperm/oocyte decision in Caenorhabditis elegans

5 July 2018

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The conserved transcriptome in human and rodent male gametogenesis

5 July 2018

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nanos function is essential for development and regeneration of planarian germ cells.

5 July 2018

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Mouse oocytes within germ cell cysts and primordial follicles contain a Balbiani body

5 July 2018

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Pathway to totipotency: lessons from germ cells

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RAP55, a cytoplasmic mRNP component, represses translation in Xenopus oocytes

5 July 2018

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Identifying genes important for spermatogonial stem cell self-renewal and survival

5 July 2018

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

5 July 2018

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RNA-associated protein 55 (RAP55) localizes to mRNA processing bodies and stress granules

5 July 2018

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The planarian Schmidtea mediterranea as a model for epigenetic germ cell specification: analysis of ESTs from the hermaphroditic strain

5 July 2018

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NF-Ya activates multiple hematopoietic stem cell (HSC) regulatory genes and promotes HSC self-renewal

5 July 2018

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Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria

5 July 2018

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Maintenance of spermatogenesis requires TAF4b, a gonad-specific subunit of TFIID.

5 July 2018

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DjPum, a homologue of Drosophila Pumilio, is essential to planarian stem cell maintenance

5 July 2018

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5 July 2018

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GLD-3 and control of the mitosis/meiosis decision in the germline of Caenorhabditis elegans

5 July 2018

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Nanos suppresses somatic cell fate in Drosophila germ line

5 July 2018

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Essential role of Plzf in maintenance of spermatogonial stem cells

5 July 2018

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Plzf is required in adult male germ cells for stem cell self-renewal

5 July 2018

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A multitude of genes expressed solely in meiotic or postmeiotic spermatogenic cells offers a myriad of contraceptive targets

5 July 2018

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ELAV inhibits 3'-end processing to promote neural splicing of ewg pre-mRNA

5 July 2018

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5 July 2018

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Conserved role of nanos proteins in germ cell development

5 July 2018

1 reference

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Poly(A)-binding proteins: multifunctional scaffolds for the post-transcriptional control of gene expression

5 July 2018

1 reference

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Characterization of DeY1, a novel Y-box gene specifically expressed in differentiating male germ cells of planarians

5 July 2018

1 reference

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The Schmidtea mediterranea database as a molecular resource for studying platyhelminthes, stem cells and regeneration

5 July 2018

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Translational repression by MSY4 inhibits spermatid differentiation in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

A zebrafish nanos-related gene is essential for the development of primordial germ cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

A sequence-specific RNA binding complex expressed in murine germ cells contains MSY2 and MSY4

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

The neuron-enriched splicing pattern of Drosophila erect wing is dependent on the presence of ELAV protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

The cis-acting RNA trafficking signal from myelin basic protein mRNA and its cognate trans-acting ligand hnRNP A2 enhance cap-dependent translation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Requirement of RBP9, a Drosophila Hu homolog, for regulation of cystocyte differentiation and oocyte determination during oogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Expression of vasa(vas)-related genes in germline cells and totipotent somatic stem cells of planarians.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Phosphorylation of histone H3 at serine 10 is correlated with chromosome condensation during mitosis and meiosis in Tetrahymena

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

hnRNP proteins and the biogenesis of mRNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Localized Bicaudal-C RNA encodes a protein containing a KH domain, the RNA binding motif of FMR1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Different requirements for conserved post-transcriptional regulators in planarian regeneration and stem cell maintenance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

The planarian nanos-like gene Smednos is expressed in germline and eye precursor cells during development and regeneration.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

A Bruno-like gene is required for stem cell maintenance in planarians.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Metazoan oocyte and early embryo development program: a progression through translation regulatory cascades.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

SMEDWI-2 is a PIWI-like protein that regulates planarian stem cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Efficient protein trafficking requires trailer hitch, a component of a ribonucleoprotein complex localized to the ER in Drosophila

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

A conserved RNA-protein complex component involved in physiological germline apoptosis regulation in C. elegans

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Nanos maintains germline stem cell self-renewal by preventing differentiation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

GLD-3, a bicaudal-C homolog that inhibits FBF to control germline sex determination in C. elegans

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

The chromosomal distribution of phosphorylated histone H3 differs between plants and animals at meiosis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Novel functions of nanos in downregulating mitosis and transcription during the development of the Drosophila germline.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

nos-1 and nos-2, two genes related to Drosophila nanos, regulate primordial germ cell development and survival in Caenorhabditis elegans

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

ELAV, a Drosophila neuron-specific protein, mediates the generation of an alternatively spliced neural protein isoform.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Essential role of the posterior morphogen nanos for germline development in Drosophila.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Toward the Elimination of Schistosomiasis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939369

Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells

28 October 2018

1 reference

12 December 2020

The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and eIF4A-dependent manner

1 reference

12 December 2020

Meiotic events at the centromeric heterochromatin: histone H3 phosphorylation, topoisomerase II alpha localization and chromosome condensation

1 reference

12 December 2020

Ultrastructural study of testis of Polycelis tenuis and Polycelis nigra (Planarians). Evolution of male germ cells before spermatogenesis

1 reference

12 December 2020

Identification and origin of the germline stem cells as revealed by the expression of nanos-related gene in planarians

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.1951010

1 reference

31 July 2017

1 reference

31 July 2017

1 reference