Efficient hypoxic activation of the anticancer agent AQ4N by CYP2S1 and CYP2W1. (Q34127983)

31 July 2017

title

Efficient hypoxic activation of the anticancer agent AQ4N by CYP2S1 and CYP2W1. (English)

1 reference

31 July 2017

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Clinton R Nishida

1

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31 July 2017

Melody Lee

series ordinal

2

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31 July 2017

Paul R Ortiz de Montellano

series ordinal

3

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31 July 2017

publication date

21 June 2010

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31 July 2017

published in

Molecular Pharmacology

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31 July 2017

volume

78

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31 July 2017

issue

3

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31 July 2017

page(s)

497-502

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Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli

31 July 2017

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A novel promoter element containing multiple overlapping xenobiotic and hypoxia response elements mediates induction of cytochrome P4502S1 by both dioxin and hypoxia

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5 July 2018

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5 July 2018

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5 July 2018

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28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20566689

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Involvement of human cytochromes P450 (CYP) in the reductive metabolism of AQ4N, a hypoxia activated anthraquinone di-N-oxide prodrug

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20566689

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/MOL.110.065045

1 reference

31 July 2017

1 reference

31 July 2017

1 reference