A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews. (Q34128155)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

0 references

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Charles Antzelevitch

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Charles Antzelevitch

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Avishag Laish-Farkash

1

object named as

Avishag Laish-Farkash

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

Michael Glikson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Dovrat Brass

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Dina Marek-Yagel

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Elon Pras

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Eyal Nof

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Haya Reznik

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Michael Eldar

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

David Luria

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

publication date

1 December 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cardiovascular Electrophysiology

8 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

1365-1372

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

Activity-dependent heteromerization of the hyperpolarization-activated, cyclic-nucleotide gated (HCN) channels: role of N-linked glycosylation

8 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated with familial asymptomatic sinus bradycardia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Physiology and pharmacology of the cardiac pacemaker ("funny") current

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Pacemaker channel dysfunction in a patient with sinus node disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Hyperpolarization-activated cation currents: from molecules to physiological function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Cardiac HCN channels: structure, function, and modulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Molecular diversity of pacemaker ion channels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Two pacemaker channels from human heart with profoundly different activation kinetics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Molecular characterization of the hyperpolarization-activated cation channel in rabbit heart sinoatrial node

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

G protein regulation of potassium ion channels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

A family of hyperpolarization-activated mammalian cation channels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Familial symptomatic sinus bradycardia: autosomal dominant inheritance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Pacemaker mechanisms in cardiac tissue.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Symptomatic sick sinus syndrome in children and adolescents as the only manifestation of cardiac abnormality or associated with unoperated congenital heart disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Sinus node dysfunction in pediatric and young adult patients: treatment by implantation of a permanent pacemaker in 39 cases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Familial occurrence of sinus bradycardia, short PR interval, intraventricular conduction defects, recurrent supraventricular tachycardia, and cardiomegaly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Molecular basis of the effect of potassium on heterologously expressed pacemaker (HCN) channels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Separable gating mechanisms in a Mammalian pacemaker channel.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Cellular expression and functional characterization of four hyperpolarization-activated pacemaker channels in cardiac and neuronal tissues

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005590

Autosomal dominant inheritance of sinus node disease

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20662977

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Organisation of the mouse sinoatrial node: structure and expression of HCN channels

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20662977

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1540-8167.2010.01844.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20662977%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference