Paradigms of growth control: relation to Cdk activation (Q34130676)

31 July 2017

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title

Paradigms of growth control: relation to Cdk activation (English)

1 reference

31 July 2017

Nancy Olashaw

1

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31 July 2017

W J Pledger

series ordinal

2

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31 July 2017

publication date

28 May 2002

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Science's STKE : signal transduction knowledge environment

31 July 2017

published in

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31 July 2017

volume

2002

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31 July 2017

issue

134

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31 July 2017

page(s)

re7

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https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

31 July 2017

1 reference

Platelets as a source of fibroblast growth-promoting activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

A Restriction Point for Control of Normal Animal Cell Proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

An ordered sequence of events is required before BALB/c-3T3 cells become committed to DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment process

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Epidermal growth factor (EGF) and somatomedin C regulate G1 progression in competent BALB/c-3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Dual control of cell growth by somatomedins and platelet-derived growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Inhibition of the mitogenic effects of plasma by a monoclonal antibody to somatomedin C

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Interleukin-2 induction of T-cell G1 progression and c-myb expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Regulation of growth and proliferation in B cell subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Inhibitors of mammalian G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Differential modulation of G1 cyclins and the Cdk inhibitor p27kip1 by platelet-derived growth factor and plasma factors in density-arrested fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cyclin D3-associated kinase activity is regulated by p27kip1 in BALB/c 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Density-dependent growth inhibition of fibroblasts ectopically expressing p27(kip1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Radiation-induced cell cycle arrest compromised by p21 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cyclins and cell cycle checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Translational control of p27Kip1 accumulation during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cell cycle-dependent phosphorylation of p27 cyclin-dependent kinase (Cdk) inhibitor by cyclin E/Cdk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Direct binding of the signal-transducing adaptor Grb2 facilitates down-regulation of the cyclin-dependent kinase inhibitor p27Kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

The p42/p44 mitogen-activated protein kinase activation triggers p27Kip1 degradation independently of CDK2/cyclin E in NIH 3T3 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Ras Activity Late in G1 Phase Required for p27kip1 Downregulation, Passage through the Restriction Point, and Entry into S Phase in Growth Factor-Stimulated NIH 3T3 Fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Sp1 and NF-Y synergistically mediate the effect of vitamin D(3) in the p27(Kip1) gene promoter that lacks vitamin D response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Differential regulation of p27(Kip1) expression by mitogenic and hypertrophic factors: Involvement of transcriptional and posttranscriptional mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Phosphatidylinositol 3' kinase: one of the effectors of Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Growth factor-dependent signaling and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Growth-factor-dependent mitogenesis requires two distinct phases of signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

D-type cyclin-dependent kinase activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Identification of G1 kinase activity for cdk6, a novel cyclin D partner

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Growth factor regulation of cyclin D1 mRNA expression through protein synthesis-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cyclin D1 is a nuclear protein required for cell cycle progression in G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Regulation of cell cycle molecules by the Ras effector system

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Multiple ras effector pathways contribute to G(1) cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

The role of cyclin D3-dependent kinase in the phosphorylation of p130 in mouse BALB/c 3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Regulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI-1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

p21-containing cyclin kinases exist in both active and inactive states

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

New functional activities for the p21 family of CDK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cyclin D-CDK subunit arrangement is dependent on the availability of competing INK4 and p21 class inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Analysis of cyclin D3-cdk4 complexes in fibroblasts expressing and lacking p27(kip1) and p21(cip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Role of the Rb/E2F pathway in cell growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Rb-mediated chromatin structure regulation and transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Retinoblastoma protein recruits histone deacetylase to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Rb interacts with histone deacetylase to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Histone deacetylases, transcriptional control, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

When the SWI/SNF complex remodels...the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Phosphorylation-dependent and -independent functions of p130 cooperate to evoke a sustained G1 block.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

E2F-4, a new member of the E2F transcription factor family, interacts with p107

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

E2F-5, a new E2F family member that interacts with p130 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Dual cyclin-binding domains are required for p107 to function as a kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

p107 and p130 Associated Cyclin A Has Altered Substrate Specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

E2F-1 but not E2F-4 can overcome p16-induced G1 cell-cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cdk2-dependent and -independent pathways in E2F-mediated S phase induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Differential effects of cdk2 and cdk3 on the control of pRb and E2F function during G1 exit

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

A novel function of adenovirus E1A is required to overcome growth arrest by the CDK2 inhibitor p27(Kip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Differential regulation of E2F transactivation by cyclin/cdk2 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Inhibition of mitogenesis in Balb/c-3T3 cells by Trichostatin A. Multiple alterations in the induction and activation of cyclin-cyclin-dependent kinase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Sequential expression of genes involved in human T lymphocyte growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Changes in p21(Cip1) and p27(Kip1) expression are not required for cell cycle entry and progression to S phase in Swiss 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Growth control in mammalian cells by cell-cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Degradation of Cyclin A Does Not Require Its Phosphorylation by CDC2 and Cyclin-dependent Kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

The stimulation of epidermal proliferation by a specific protein (EGF)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Purification of human interleukin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Hypoxia inhibits G1/S transition through regulation of p27 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Permanent growth arrest in irradiated human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Association of human cyclin E with a periodic G1-S phase protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Skp2 induction and phosphorylation is associated with the late G1 phase of proliferating rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

K-ras modulates the cell cycle via both positive and negative regulatory pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Phosphatidylinositol 3-kinase inhibitors block aortic smooth muscle cell proliferation in mid-late G1 phase: effect on cyclin-dependent kinase 2 and the inhibitory protein p27KIP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Ubiquitination of free cyclin D1 is independent of phosphorylation on threonine 286

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Cdk2-dependent phosphorylation and functional inactivation of the pRB-related p130 protein in pRB(-), p16INK4A(+) tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Requirements for cell cycle arrest by p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

p27Kip1 regulates T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

Interdependence of cdk2 activation and interleukin-2Ralpha accumulation in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2002.134.RE7

10.1126/STKE.2002.134.RE7

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference