Signaling through the small G-protein Cdc42 is involved in insulin-like growth factor-I resistance in aging articular chondrocytes (Q34130808)

31 July 2017

title

Signaling through the small G-protein Cdc42 is involved in insulin-like growth factor-I resistance in aging articular chondrocytes (English)

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31 July 2017

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1

Lisa A Fortier

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31 July 2017

Brian J Miller

2

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31 July 2017

publication date

1 August 2006

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Journal of Orthopaedic Research

31 July 2017

published in

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31 July 2017

volume

24

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31 July 2017

issue

8

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31 July 2017

page(s)

1765-1772

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Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function

31 July 2017

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Crossref

https://api.crossref.org/works/10.1002%2FJOR.20185

21 January 2018

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28 October 2018

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Hypoxia-induced nitric oxide protects chondrocytes from damage by hydrogen peroxide

28 October 2018

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Insulin-like growth factor-I diminishes the activation status and expression of the small GTPase Cdc42 in articular chondrocytes

28 October 2018

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Increased oxidative stress with aging reduces chondrocyte survival: correlation with intracellular glutathione levels

28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis.

28 October 2018

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28 October 2018

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12 December 2020

Human osteoarthritic chondrocytes possess an increased number of insulin-like growth factor 1 binding sites but are unresponsive to its stimulation. Possible role of IGF-1-binding proteins

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12 December 2020

Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease

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12 December 2020

Biomechanical regulation of matrix metalloproteinase-9 in cultured chondrocytes

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12 December 2020

Retarded intracellular lipid transport associated with reduced expression of Cdc42, a member of Rho-GTPases, in human aged skin fibroblasts: a possible function of Cdc42 in mediating intracellular lipid transport

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12 December 2020

Growth promoting peptides in osteoarthritis and diffuse idiopathic skeletal hyperostosis--insulin, insulin-like growth factor-I, growth hormone

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12 December 2020

Effects of basic fibroblast growth factor, transforming growth factor-beta 1, insulin-like growth factor-1, and insulin on human osteoarthritic articular cartilage explants

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12 December 2020

Insulin-like growth factor (IGF) receptor, IGF-I, interleukin-1 beta (IL-1 beta), and IL-6 mRNA expression in osteoarthritic and normal human cartilage

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12 December 2020

Production of binding proteins and role of the insulin-like growth factor I binding protein 3 in human articular cartilage explants

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1002/JOR.20185

1 reference

31 July 2017

1 reference

31 July 2017

1 reference